Dual-wavelength retinal vessel blood oxygen measuring system based on fundus camera

Abstract

The invention relates to a dual-wavelength retinal vessel blood oxygen measuring system based on a fundus camera. The system comprises two parts, namely, a retinal image acquisition subsystem and a blood oxygen calculation subsystem, wherein the retinal image acquisition subsystem forms a retinal image acquired by the fundus camera to infinity through an imaging objective, and a telecentric beam path in the image space is formed. A right-angled reflecting prism splits a light beam into two ways, the light beam is reflected by reflectors and transmits interference filters with specific wavelengths to be filtered into imaging light with required wavelengths, the imaging light is imaged on a CCD (charge coupled device) target surface simultaneously after passing through the imaging objective, and dual-wavelength simultaneous retinal imaging is realized; the blood oxygen calculation subsystem finishes calculation of the retinal vessel blood oxygen saturation after performing a series of operations such as image processing, vessel extraction, light density calculation and the like on an acquired dual-wavelength retinal image. With the adoption of the system, retinal vessel function information is acquired while the retinal structure image is acquired, and a powerful tool can be provided for life science related research and diagnosis of fundus related diseases.

Description

technical field [0001] The invention relates to a dual-wavelength retinal blood vessel blood oxygen measurement system based on a fundus camera. Background technique [0002] Retinal blood vessels provide an important indicator in the clinical diagnosis and treatment of ophthalmic diseases. Many retinal lesions will cause a large amount of oxygen consumption, resulting in changes in blood oxygen saturation, such as diabetic retinopathy, glaucoma, and vascular occlusion. In addition, retinal tissue and blood vessels are the only deep structures of the human body that can be directly observed, and are an important window to understand certain systemic diseases, such as changes in retinal blood vessels, hypertension and other cardiovascular diseases. Therefore, processing and analyzing retinal images to obtain functional information on its structure and blood oxygen saturation is of great significance for early diagnosis and detection of diseases. [0003] Obtaining retinal im...

AI Technical Summary

Problems solved by technology

However, there are still some deficiencies in the above studies: for example, the dual-wavelength image uses different imaging channels, the optical path is complex, and there are many optical elements; the use of two cameras to collect dual-wavelength retinal images is expensive; Oxygen measurement brings impact and more

In order to observe and evaluate the retina as a whole under a large field of view, software puzzles are required, which is time-consuming and laborious

In addition, the patent collects two fundus images with different wavelengths by time-sharing, and the collection time cannot be completely consistent, and the influence of human eye movement on the accuracy of blood oxygen calculation cannot be avoided.

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