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Hawthorn fruit-coated tablet, and preparation method thereof

A technology of coating and hawthorn, which is applied in the field of medicine, can solve the problems of poor improvement effect, and achieve the effect of avoiding peak and valley phenomenon, good taste and good adhesion effect

Inactive Publication Date: 2015-11-04
FUJIAN NETDRAGON WEBSOFT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Such as: dispersible tablets, orally disintegrating tablets, chewable tablets, granules, oral liquid preparations, powders, dry suspensions, etc. Although they are easy to take, for drugs with less bad taste, the taste must be improved by adding flavoring agents, etc. But the improvement effect is not good

Method used

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Examples

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Effect test

preparation example Construction

[0021] The present invention provides a kind of preparation method of the above-mentioned hawthorn-coated tablet, comprising the steps of:

[0022] Step 1: Beat the hawthorn into a slurry, pass through a sieve with a pore size of 1.2mm, filter and sterilize to obtain the pulp;

[0023] Step 2: beat the fruit pulp twice, pass through a sieve with an aperture of 0.5mm, then add sucrose and starch, stir evenly, refine the pulp with a colloid mill, pass through a sieve with an aperture of 0.15mm, and obtain the mixed fruit pulp;

[0024] Step 3: use the mixed fruit pulp as a coating layer to coat the surface of the drug layer, and dry to obtain hawthorn-coated tablets.

[0025] Preferably, in the preparation method of the above-mentioned hawthorn-coated tablet, the preparation method is specifically:

[0026] Step 1: Select fresh hawthorns, remove injured, rotten and shrunken fruits, wash with water and drain; add water to hawthorns at a ratio of 1:2, control the temperature at 9...

Embodiment 1

[0030] A hawthorn-coated tablet, comprising a drug layer and a coating layer coated outside the drug layer, the ratio by weight of the drug layer to the coating layer is 10:3, and the coating layer consists of the following parts by weight: Raw materials are mixed together: 2 parts of starch, 1 part of sucrose, and 8 parts of hawthorn. The medicine layer is medicine for treating hypertension and hyperlipidemia.

[0031] The preparation method of the tablet coated with the above-mentioned hawthorn is:

[0032] Step 1: Select fresh hawthorns, remove injured, rotten and shrunken fruits, wash with water and drain; add water to hawthorns at a ratio of 1:2, control the temperature at 95°C, keep for 20 minutes, then cool naturally, remove the pulp, Pour into the first feeder to beat into slurry, pass through a sieve with an aperture of 1.2mm, filter out seeds, cores, stems, calyx and impurities, and sterilize to obtain fruit pulp;

[0033] Step 2: Pour the pulp into the second beat...

Embodiment 2

[0036] A hawthorn-coated tablet, comprising a drug layer and a coating layer coated outside the drug layer, the ratio by weight of the drug layer to the coating layer is 10:2, and the coating layer consists of the following parts by weight: The ratio of raw materials is mixed: 1 part of starch, 0.5 part of sucrose, and 9 parts of hawthorn. The medicine layer is medicine for treating hypertension and hyperlipidemia.

[0037] The preparation method of the tablet coated with the above-mentioned hawthorn is:

[0038] Step 1: Select fresh hawthorn, remove injured, rotten and shrunken fruits, wash with water and drain; add water to hawthorn at a ratio of 1:2, control the temperature at 97°C, keep for 25 minutes, then cool naturally, remove the pulp, Pour into the first feeder to beat into slurry, pass through a sieve with an aperture of 1.2mm, filter out seeds, cores, stems, calyx and impurities, and sterilize to obtain fruit pulp;

[0039] Step 2: Pour the pulp into the second be...

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PUM

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Abstract

The invention belongs to the technical field of medicine, and more specifically relates to a hawthorn fruit-coated tablet, and a preparation method thereof. The hawthorn fruit-coated tablet comprises a medicine layer and a coating layer used for coating the medicine layer; weight ratio of the medicine layer to the coating layer ranges from 10:2 to 10:4; and the coating layer is prepared via mixing of, by weigth, 1 to 2 parts of starch, 0.5 to 1 part of sucrose, and 8 to 10 parts of hawthorn fruit. The outer layer of the hawthorn fruit-coated tablet is coated with the coating layer prepared from hawthorn fruit, so that the hawthorn fruit-coated tablet possesses the taste and mouthfeel of hawthorn fruit, and is better for taking; drug properties of hawthorn fruit are mild, so that drug properties of the hawthorn fruit-coated tablet are not influenced; combination of the coating layer with the medicine layer is firm, coating is compact, hawthorn fruit possesses bacteria inhibiting ingredients, so that hawthorn fruit is more beneficial to tablet preservation compared with other fruits.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a hawthorn-coated tablet and a preparation method thereof. Background technique [0002] Oral administration is the most commonly used way of administration, and there are many types of preparations, but there are various problems for different users. Such as: dispersible tablets, orally disintegrating tablets, chewable tablets, granules, oral liquid preparations, powders, dry suspensions, etc. Although they are easy to take, for drugs with less bad taste, the taste must be improved by adding flavoring agents, etc. But the improvement effect is not good. Contents of the invention [0003] The technical problem to be solved by the present invention is to provide a hawthorn-coated tablet with good taste and low preparation cost and a preparation method thereof. [0004] In order to solve the above-mentioned technical problems, the technical solution adopted in the present inve...

Claims

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Application Information

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IPC IPC(8): A61K47/46A61K9/36A61K31/47A61P9/12A61P3/06A61P9/10
Inventor 刘德建
Owner FUJIAN NETDRAGON WEBSOFT