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A microinjection mechanism based on stick-slip driving principle

A microinjection and stick-slip technology, applied in the direction of using microinjection, biomass post-processing, biological material pretreatment, etc., can solve the problems of large cell damage and large inertial impact force, and achieve small cell damage and high precision. , the effect of simple structure

Active Publication Date: 2017-03-08
苏州博致医疗科技有限公司
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Problems solved by technology

This device uses piezoelectric ceramics to directly drive the microneedle to obtain displacement feeding, but since the feeding displacement of the injection needle is output by piezoelectric ceramics at one time, it will generate a large inertial impact force and cause great damage to cells. , while the direct output displacement of piezoelectric ceramics is small and can only reach a few microns

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  • A microinjection mechanism based on stick-slip driving principle
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  • A microinjection mechanism based on stick-slip driving principle

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Embodiment Construction

[0031] As mentioned in the background technology, the existing microinjection device uses piezoelectric ceramics to directly drive the microneedle to obtain displacement feed, but since the feeding displacement of the injection needle is output by piezoelectric ceramics at one time, it will produce a lot of Large inertial impact force will cause greater damage to cells, while the direct output displacement of piezoelectric ceramics is small, only a few microns.

[0032] Next, the specific technical solution of the present invention will be introduced in detail.

[0033] See figure 1 , the microinjection mechanism in the present invention includes a piezoelectric ceramic 2, a fixed connecting rod 1, a microinjector 8, a slider 3, an upper slide 9, and a lower slide 4, and the piezoelectric ceramic 2 adopts stacked piezoelectric ceramics, The piezoelectric ceramic 2 and the slider 3 are connected by threads to transmit the displacement, the fixed connecting rod 1 is placed on o...

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Abstract

A microinjection mechanism based on the stick-slip driving principle comprises stacking piezoelectric ceramic, a fixing rod of the stacking piezoelectric ceramic, a microinjection device, a sliding block, an upper sliding platform, a lower sliding platform, a spring and a plurality of auxiliary fixing pieces; output displacement of the piezoelectric ceramic is transferred with the stick-slip driving principle, the precision of output displacement of the microinjection device can be guaranteed, and the larger displacement travel can be obtained. Meanwhile, when the microinjection device is driven with the stick-slip driving principle to operate cells, the certain displacement feed can be operated in multiple steps, so that the inertia force produced by each step of small displacement is smaller, and damage to the cells is smaller. Meanwhile, the microinjection mechanism is simple in structure and suitable for mass production.

Description

technical field [0001] The invention relates to the technical field of microinjection equipment, in particular to a microinjection mechanism based on the stick-slip driving principle. Background technique [0002] In bioengineering, micromanipulation is the key to regenerative technologies such as cell culture and gene injection, and the automation of microinjection plays a significant role in promoting the development of bioengineering. The microinjector is an essential device for cell nucleus transplantation, microinjection and transgene injection in the field of biological sciences, and the microinjection mechanism is the key mechanism in the fiber injection process. Existing cell injection generally adopts mechanical transmission, hydraulic ball hinge and other driving methods for microinjection. In order to reduce the cell deformation caused by microinjection acupuncture membrane, the operator mostly uses the injection needle back suction method on the cell membrane. A...

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M1/00
CPCC12N15/89
Inventor 汝长海潘鹏庞博慧庞明
Owner 苏州博致医疗科技有限公司
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