Antibacterial peptide immunomodulatory feed additive for pigs

Abstract

The present invention discloses an antibacterial peptide immunomodulatory feed additive for pigs. The feed additive consists of the following components in parts by weight 1-5 parts of bacillus amyloliquefaciens SC06 at a concentration of 10^9 cfug, 1 part of pidotimod, 3 parts of zeolite powder, and 1-5 parts of corn starch. The antibacterial peptide immunomodulatory feed additive for pigs can overcome many problems including pig body immunosuppression, low disease resistance, slow growth, etc. in the current breeding process, and the antibacterial peptide immunomodulatory feed additive for pigs has characteristics of being easy in preparation, easy to use, significant in effects, etc., and thus is very good in promotion and use values.

Description

technical field

[0001] The invention provides the preparation and application of a bacteriocin immunoregulatory feed additive for pigs. Background technique

[0002] Immunosuppression is common in pig breeding at present, which is caused by various factors, including pathogenic bacteria infection (such as blue ear disease, circovirus disease, pseudorabies, swine fever, parvovirus disease, swine influenza, parvovirus virus and asthma, Haemophilus parasuis, infectious pleuropneumonia, salmonellosis, bacteria such as Eperythrozoonosis, and parasitic infections such as toxoplasmosis) and non-infectious factors, among which there are Toxin poisoning (mycotoxins: such as aflatoxin, zearalenone, T-2 toxin, fumonisin, ochratoxin, etc.), irrational use of antibiotics and drugs (such as chloramphenicol, furazolidone, streptoxin, etc.) neomycin, gentamicin, kanamycin, corticosteroids, tetracycline, oxytetracycline, prednisone, cortisone, androgens, testosterone, sulfa drugs, etc.), nu...

Examples

Embodiment 1

[0017] Embodiment 1, preparation of bacteriocin immunomodulatory feed additive for pigs

[0018] Weigh Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacterium powder 20 kg, pidotimod powder (above 99% purity) 10 kg, zeolite powder 30 kg, cornstarch 40 kg; fully mixed and sub-packed into 1 kg package, ready to use.

[0019] application test

[0020] 1 test material

[0021] Du Changwai Sanyuan newborn piglets were provided by Zhejiang Xinxin Feed Co., Ltd.

[0022] Bacillus amyloliquefaciens additive: take Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacteria powder 30 kg, zeolite powder 30 kg, cornstarch 40 kg; mix well before use.

[0023] Pidotimod additive: take by weighing 30 kg of pidotimod powder (purity above 99%), 30 kg of zeolite powder, and 40 kg of cornstarch; use after fully mixing.

[0024] 2 Feeding experiment and daily management method

[0025] In this experiment, a single-factor randomized design was adopted, and healthy early-weaned piglets were divided ...

Embodiment 2

[0051] Embodiment 2, preparation of bacteriocin immunomodulatory feed additive for pigs

[0052] Weigh Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacteria powder 40 kg, pidotimod powder (above 99% purity) 10 kg, zeolite powder 30 kg, cornstarch 20 kg; fully mixed and sub-packed into 1 kg package, ready to use.

Embodiment 3

[0053] Example 3, Preparation of bacteriocin immunomodulatory feed additive for pigs

[0054] Weigh Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacterium powder 10 kg, pidotimod powder (above 99% purity) 10 kg, zeolite powder 30 kg, cornstarch 50 kg; fully mixed and sub-packed into 1 kg package, ready to use.

technical field

[0001] The invention provides the preparation and application of a bacteriocin immunoregulatory feed additive for pigs. Background technique

[0002] Immunosuppression is common in pig breeding at present, which is caused by various factors, including pathogenic bacteria infection (such as blue ear disease, circovirus disease, pseudorabies, swine fever, parvovirus disease, swine influenza, parvovirus virus and asthma, Haemophilus parasuis, infectious pleuropneumonia, salmonellosis, bacteria such as Eperythrozoonosis, and parasitic infections such as toxoplasmosis) and non-infectious factors, among which there are Toxin poisoning (mycotoxins: such as aflatoxin, zearalenone, T-2 toxin, fumonisin, ochratoxin, etc.), irrational use of antibiotics and drugs (such as chloramphenicol, furazolidone, streptoxin, etc.) neomycin, gentamicin, kanamycin, corticosteroids, tetracycline, oxytetracycline, prednisone, cortisone, androgens, testosterone, sulfa drugs, etc.), nu...

Examples

Embodiment 1

[0017] Embodiment 1, preparation of bacteriocin immunomodulatory feed additive for pigs

[0018] Weigh Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacterium powder 20 kg, pidotimod powder (above 99% purity) 10 kg, zeolite powder 30 kg, cornstarch 40 kg; fully mixed and sub-packed into 1 kg package, ready to use.

[0019] application test

[0020] 1 test material

[0021] Du Changwai Sanyuan newborn piglets were provided by Zhejiang Xinxin Feed Co., Ltd.

[0022] Bacillus amyloliquefaciens additive: take Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacteria powder 30 kg, zeolite powder 30 kg, cornstarch 40 kg; mix well before use.

[0023] Pidotimod additive: take by weighing 30 kg of pidotimod powder (purity above 99%), 30 kg of zeolite powder, and 40 kg of cornstarch; use after fully mixing.

[0024] 2 Feeding experiment and daily management method

[0025] In this experiment, a single-factor randomized design was adopted, and healthy early-weaned piglets were divided ...

Embodiment 2

[0051] Embodiment 2, preparation of bacteriocin immunomodulatory feed additive for pigs

[0052] Weigh Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacteria powder 40 kg, pidotimod powder (above 99% purity) 10 kg, zeolite powder 30 kg, cornstarch 20 kg; fully mixed and sub-packed into 1 kg package, ready to use.

Embodiment 3

[0053] Example 3, Preparation of bacteriocin immunomodulatory feed additive for pigs

[0054] Weigh Bacillus amyloliquefaciens SC06 (10 9 cfu / g) bacterium powder 10 kg, pidotimod powder (above 99% purity) 10 kg, zeolite powder 30 kg, cornstarch 50 kg; fully mixed and sub-packed into 1 kg package, ready to use.

Images