31results about How to "Overcome inhibition" patented technology

The invention relates to biomass supercritical and subcritical combined continuous type pretreatment and hydrolysis equipment and a method. The equipment comprises a water storage tank, a material storage tank with a stirring device, a preheating system, a supercritical reaction system, a primary cooling system, a subcritical reaction system, a final cooling system, a product collection system and an electronic temperature controlling system. The method comprises the following processing steps: water reaching preheat temperature and biomass material paste are rapidly mixed and then injected into the supercritical reaction system to be pretreated under supercritical condition; the reaction product is cooled through the primary cooling system and depressurized through a pressure reducing valve and then enters into the subcritical reaction system to be hydrolyzed sequentially, therefore fermentable sugars are continuously generated and collected. The invention utilizes the advantages of the supercritical method that the reaction is rapid, activator is not required and product inhibition does not exit, realizes that the continuous hydrolysis conversion of wood fiber biomass can generate fermentable sugars, is the foundation of subsequent resource recovery technologies, such as ethanol production by fermentation and the like, and has wide application prospect.

The invention discloses a treatment method of antibiotic fermenting bacterial residues. The treatment method comprises the following steps: uniformly mixing the fermenting bacterial residues of lincomycin hydrochloride and gentamicin with water, and preparing a suspension; performing anaerobic fermentation treatment on the suspension. The treatment method is an efficient fermentation treatment process of the fermenting bacterial residues of lincomycin hydrochloride and gentamicin and belongs to the technical field of resource utilization of the bacterial residues. By adopting the method disclosed by the invention, the toxicity, the harm and an inhibition effect of residual antibiotics to fermenting bacteria in an anaerobic fermentation process of the traditional antibiotic bacterial residues are overcome, the problems of blockage, short flow and the like which are produced when a traditional filler is fed are simultaneously avoided, the biomass of a hydrolysis acidification pool and an L-fermentation tank is ensured, the gas production is improved and the method further has the advantages of low treatment cost, easiness in control of operation process, high load of a reactor matched with the method, small occupied area and the like.

The invention discloses a transreceiver and a zero intermediate frequency emission calibrating method. The transreceiver comprises a zero intermediate frequency emission circuit and a receiving circuit, and also comprises a coupling module and a calibration parameter adjusting module, wherein the coupling module is arranged between the zero intermediate frequency emission circuit and the receiving circuit, and is used for coupling radio-frequency signals of the emission circuit to the receiving circuit; and the calibration parameter adjusting module is arranged on the receiving circuit, used for adjusting unbalance factors of the coupled signals in a close loop to make the signal quality index meet the predetermined demand, and uses the adjusted unbalance factors as calibration parametersto calibrate the emission signals of the emission circuit. The method of the invention can adaptively adjust the calibration parameters of the zero intermediate frequency signals with lower cost according to environmental requirements.

The invention discloses a preparation method of natural spice 2-phenethyl alcohol, which is implemented by selecting Candida drusei, Saccharomyces cerevisiae, Kluyveromyces marxianus, inoculating cultivated seed liquid or active dried yeast powder into fermentation culture medium, taking L-PHE produced by fermentation method or enzyme method as substrate, performing liquid aerobic fermentation in a fermentation shake flask or a fermentation tank, adding solid phase absorption medium, L-PHE and glucose in the process of fermentation, obtaining the solid phase absorption medium in a filtration or centrifugation manner, then adopting an elution solvent to carry out elution on the absorption medium, further distilling the eluent to obtain the natural 2-phenethyl alcohol with purity of 97.5-99.5%. The invention combines the fermentation and absorption separation of 2-phenethyl alcohol, has low production cost and excellent aroma quality of the product.

The present invention relates to the use of proteins that are differentially expressed in tumor associated stromal cells, as compared to normal stromal, as biomolecular targets for tumor treatment therapies. The present invention also provides compounds and pharmaceutically acceptable compositions for administration in the methods of the invention.

Disclosed is a facility tomato supplemental lighting adjustment and control method based on a growth model. Three growth stages of the tomato seedling stage, the flowering stage and the fruiting stage are selected, the tomato leaf net photosynthetic rates at different temperatures and with concentrations of carbon dioxide and light intensities are measured, corresponding light saturation points at different temperatures and with concentrations of carbon dioxide are obtained, and a tomato optimized light saturation point model is built; the temperature, the concentration of carbon dioxide and the light intensity in the tomato growth environment are monitored in real time, whether the current light intensity is at the light saturation point corresponding to the current temperature and the current concentration of carbon dioxide is judged according to the growth stage of tomatoes and the tomato optimized light saturation point model, and if not, an LED light source is used for light supplementation until the light intensity reaches the light saturation point. The invention further provides a facility tomato supplemental lighting adjustment and control system based on the growth model, intelligent and quantitative light supplementation of the tomatoes is achieved, and great significance is brought to energy-saving and high-efficiency production of the facility tomatoes.

The invention provides a three-dimensional complex cell aggregate model as well as a preparation method and application thereof. According to the model, a natural or chemically synthesized polymer is used as a matrix material to prepare submicron-scale microspheres, and cell factors are embedded in or fixed on the surface of the submicron-scale microspheres and are co-cultured with cells to form a complex cell aggregate containing the microspheres, so that the biological activity of the cells in the aggregate can be regulated and controlled from inside to outside. The model can be used for researches of propagation and differentiation of stem cells in a three-dimensional state, overcomes the problems that the cell aggregate is heterogeneous in composition/structure, the cell proliferation efficiency is low and the directional induced differentiation efficiency is low due to non-uniform mass transfer and short acting time of liquid factors in a culture medium during the traditional three-dimensional culture of the stem cells, can be used for stimulating interaction between cells and cells, cells and an extracellular matrix as well as cells and soluble factors, thereby providing a theoretical and technical support for in vitro construction and optimization of a stem cell culture technology, and tissue engineering construction of various tissue and organ analogs or equivalents.

The present invention relates, generally, to methods and compositions for increasing the efficiency of therapeutic antibodies. Their efficiency is enhanced through the increase of the ADCC mechanism. More particularly, the invention relates to the use of a therapeutic antibody in combination with compounds that block an inhibitory receptor or stimulate an activating receptor of an NK cell in order to enhance the efficiency of the treatment with therapeutic antibodies in human subjects.

The present invention discloses a parallel power conversion control device for a parallel power conversion system. The parallel power conversion control device for the parallel power conversion system comprises a total current instruction generator, an average current instruction generator, an average feedback current calculator, a current controller, a circulation calculator, a circulation controller configured to control the circulation of power convertors and output circulation offset voltage signals according to the results calculated by the circulation calculator, and a modulating signal generator configured to generate modulation signals required by pulse width modulation of a PWM unit according to the control voltage signals output by the current controller and the circulation offset voltage signals output by the circulation controller. The parallel power conversion control device for a parallel power conversion system is able to effectively improve the tracking performance and the circulation inhibition effect of total output current to a total current instruction value, and effectively reduce the calculated load of a microprocessor.

Disclosed is a pretreatment method for biomass material, which comprises the steps: by adopting a nanometer grinding device, corn leaves and straw stalks are ground with the size rang between 10 micrometres to 20 micrometres, so the cellulose crystal thereof is exposed on the surface to be directly hydrolyzed with a hydrolysis efficiency of 96 percent which is identical to that of the sample split through the splitting method of phosphoric acid acetone. The pretreatment method can replace other pretreatment methods requiring chemical reagent, both the cost and the environmental pollution are reduced, and the pretreatment method is a promising raw material pretreatment technique which utilizes lignocellulose to produce biological energy sources or useful chemicals.

The invention relates to a coupling signal suppression circuit in a quartz tuning fork gyroscope. After signals output by a quartz tuning fork sensitive electrode pass through a static coupling suppression circuit, static coupling signals in a common mode state are effectively suppressed, and useful signals and differential mode interference signals are amplified; signals output by the static coupling suppression circuit are subjected to phase adjustment to ensure that the phase of mechanical coupling signals and the phase of related detection signals are orthogonal; and phase adjustment quantity realized by a phase adjustment circuit is marked as sigma, and the phase adjustment generates cos sigma gain for finally output useful signals and generates sin sigma gain for the mechanical coupling signals. The invention overcomes the defects that the traditional single-electrode detection circuit cannot suppress static coupling signals and cannot effectively suppress vibration coupling by adopting the technical scheme of double-electrode charge differential amplification and vibration coupling phase adjustment, not only completely suppresses the static coupling signals, but also provides conditions for effectively suppressing vibration coupling, and therefore, the performance of the microquartz tuning fork gyroscope is improved.

The invention discloses a parallel power conversion control device which comprises a total current instruction generator, a weight coefficient determination unit, a total current instruction distributor, a feed current calculator, a current controller, a circular current calculator, a circular current controller and a modulating signal generator, wherein the circular current calculator is used for calculating circular current of a corresponding power converter according to an output current value of the power converter; the circular current controller is used for controlling circular current of the power converter according to the calculation result of the circular current calculator and outputting a circular current compensation voltage signal; the modulating signal generator is used for generating a modulating signal required by a PWM (Pulse-Width Modulation) unit to carry out pulse wide modulation according to a control voltage signal outputted by the current controller and the circular current compensation voltage signal outputted by the circular current controller. According to the parallel power conversion control device disclosed by the invention, tracking performance and circular current inhibiting effect of total output current on a total current instruction value can be effectively improved, and the calculation load of a microprocessor is effectively reduced.

The invention relates to a method for hydrolyzing straw by continuous reaction of ultra-low acid. The method comprises the following steps of: grinding the straw to be 2-200 meshes; adding the straw and dilute acid with the pH of 3-7 into a high pressure reactor in a weight ratio of 1: (6-12), and stirring; sealing the high pressure reactor, opening condensate water and heating the high pressure reactor; when the high pressure reactor is heated up to 180-250 DEG C, opening a sampling pump, wherein the flow rate of the sampling pump is 0.5-3 times of the volume of the reactor per hour; adjusting the position of an air compression valve; in the reaction process, maintaining the pressure to be 22.1-40.0MPa and the temperature to be 240-415 DEG C; opening the air outlet of the reactor and a pressure control valve connected with the air outlet; and collecting a liquid flowing out of the pressure control valve. The method can be used for separating reducing sugar generated in the reactor in time and separating poisonous substance, thus improving the yield of the reducing sugar and being beneficial to improvement of the yield of alcohol produced by fermentation.

The invention discloses a centimeter wave/millimeter wave ultra-wideband signal generation device based on combination of a microwave photon external modulation technology and an up-conversion technology, and belongs to the technical field of microwave photonics. The device comprises a laser source, a coupler 1, a coupler 2, a polarization controller 1, a polarization controller 2, a double-parallel Mach-Zehnder modulator, a Mach-Zehnder modulator, an arbitrary waveform generator, a microwave signal source, a direct-current voltage-stabilizing source 1, a direct-current voltage-stabilizing source 2, a direct-current voltage-stabilizing source 3, a direct-current voltage-stabilizing source 4, an erbium-doped optical fiber amplifier, an adjustable optical filter, an adjustable optical delay line, a balanced photoelectric detector, a spectrum analyzer and an oscilloscope. The device can generate centimeter-wave ultra-wideband signals and millimeter-wave ultra-wideband signals, and is suitable for an indoor ultra-wideband communication system and an outdoor ultra-wideband radar system. Compared with other methods, the method for realizing the up-conversion technology based on single side band modulation has better flexibility and stability, and is more suitable for transmission of ultra-wideband signals in long-distance optical fibers.

The invention discloses an active power filter based on a nonlinear tracking differentiator and an arithmetic circuit thereof. The filer comprises a voltage loop outputting the difference between themeasured actual value of a DC side voltage and a voltage reference value; a PI controller and a proportional integral controller are connected to the output of the voltage loop for outputting a corresponding reference current; a nonlinear differential tracker connected to the proportional integral controller and capable of more rapidly tracking a reference current and the derivative signal, and filtering the harmonics in the reference current; a phase-locked loop generating a unit sinusoidal voltage signal in the same phase and same frequency with a grid side voltage and detecting the voltagephase on the grid side; and a multiplier connecting with the outputs of the nonlinear tracking differentiator and the phase locked loop to obtain a reference value of the current on the grid side . According to the invention, the dynamic performance of the active power filter is greatly improved under the premise of shortening the reaction time, and the reference current can maximize the suppression of harmonics.

The invention relates to a novel eukaryotic recombinant protein with a tumor inhibition effect and a preparation method thereof and belongs to the field of medical bioengineering. The novel eukaryotic recombinant protein with a tumor inhibition effect comprises 132 amino acids, 1th-25th amino acids form an NLS sequence, 26th-39th amino acids form a His-FLAG label sequence, 42th-121th amino acids form an N240 sequence, 122th-132th amino acids form a TAT sequence and the His-FLAG label sequence is bonded with the N240 sequence through two RS amino acids. The novel eukaryotic recombinant protein solves the problem that the existing small molecular drug cannot obstruct bonding of TCF4 and other cancer genes but beta-catenin so that the existing small molecular drug cannot effectively inhibit tumor stem cells, realizes comprehensive blocking of bonding of TCF4 and a protooncogene, effectively inhibits tumor stem cells and improves chemotherapeutic drug sensitivity.

The invention relates to the technical field of medical detection, and particularly discloses a compound preservative, a preparation method and application thereof, a blood glucose quality control liquid containing the compound preservative, and a preparation method and application of the blood glucose quality control liquid. The compound preservative comprises the following component: epsilon-polylysine; glycine; sodium benzoate; xylitol; and tween-20. The invention further discloses a preparation method and application of the compound preservative. The blood glucose quality control liquid comprises the following components: the compound preservative; a thickening agent; citric acid; trisodium citrate; glucose; a food colorant; and water. The invention further discloses a preparation method and application of the blood glucose quality control liquid. The blood glucose quality control liquid prepared by utilizing the compound preservative provided by the invention is high in biological safety, environment-friendly, broad-spectrum, efficient and high in stability, has a relatively good preservative effect, and can ensure that glucose is not easy to degrade.

The invention discloses a planetary reducer external interference suppression method based on a wavelet threshold. The method comprises the following steps: obtaining the vibration data of the surfaces of two adjacent gearboxes of a planetary reducer, namely first vibration data and second vibration data; performing multilayer discrete wavelet decomposition to obtain a first wavelet detail coefficient, a first wavelet approximation coefficient and a second wavelet detail coefficient; carrying out adaptive wavelet threshold processing on the wavelet detail coefficients to obtain wavelet detail coefficients of each layer after threshold processing; and performing wavelet reconstruction on the first wavelet approximation coefficient and the wavelet detail coefficient of each layer after threshold processing, wherein the reconstructed data is the data after external interference suppression. According to the method, the problem that an adaptive wavelet threshold method is easy to cause over-suppression or insufficient suppression is solved, the wavelet detail coefficient characteristics of the vibration data with relatively high cross-correlation degree are kept while the random interference influence is effectively suppressed, and the precision of state monitoring and fault diagnosis of the planetary reducer is improved.

The present invention discloses an antibacterial peptide immunomodulatory feed additive for pigs. The feed additive consists of the following components in parts by weight 1-5 parts of bacillus amyloliquefaciens SC06 at a concentration of 10^9 cfug, 1 part of pidotimod, 3 parts of zeolite powder, and 1-5 parts of corn starch. The antibacterial peptide immunomodulatory feed additive for pigs can overcome many problems including pig body immunosuppression, low disease resistance, slow growth, etc. in the current breeding process, and the antibacterial peptide immunomodulatory feed additive for pigs has characteristics of being easy in preparation, easy to use, significant in effects, etc., and thus is very good in promotion and use values.

The invention discloses a radio frequency front-end circuit and a filtering method thereof, and electronic equipment, the radio frequency front-end circuit comprises a first radio frequency path and a second radio frequency path, the first radio frequency path is used for transmitting a first signal, the second radio frequency path is used for transmitting a second signal, and the first signal and the second signal correspond to different frequency bands. Each radio frequency path comprises an input port and an output port; the filters are arranged between the input port and the output port, the cut-off frequencies of the N filters are different, and N is an integer greater than 1; and the gating unit is used for gating at least one of the N filters to be serially connected between the input port and the output port so as to form a filtering path, and the filtering path is used for reducing interference of signals transmitted by non-radio frequency paths where the filtering path is located on signals transmitted by the radio frequency paths where the filtering path is located. The circuit can effectively suppress out-of-band noise, and alleviate the problem of mutual interference of different signals in similar frequency bands or in the frequency bands.

The invention provides a high-frequency core-shell structure micro-droplet ejection device. The high-frequency core-shell structure micro-droplet ejection device comprises a nozzle sheath, a nozzle inner layer, a needle core, a sheath controllable liquid supply device, an inner layer controllable liquid supply device, a sheath waveform programmable power supply, an inner layer waveform programmable power supply, a sheath waveform high voltage amplifier and an inner layer waveform high voltage amplifier; the nozzle inner layer is embedded in the nozzle sheath; and an nozzle inner layer insulating layer is arranged on the surface of the nozzle inner layer. A voltage and a frequency of a high voltage power supply are controlled to be matched with the properties of a solution by independent power supply control to the nozzle sheath and the nozzle inner layer, so that the precise regulation of the volume of micro-droplets and a multi-core wrapped core-shell structure is realized, and the high-frequency vibration needle core is introduced to promote the flow of a micro interface of the solution, so that the simultaneous ejection of a sheath solution and an inner layer solution which havethe high viscosity difference and the core-shell wrapping are realized, and the ejection frequency of the core-shell structure micro-droplets is improved.

The invention discloses a laser radar receiving optical system based on an optical micro switch. The laser radar receiving optical system comprises an imaging optical assembly, the optical micro switch and a stray light feedback assembly. The imaging optical assembly is used for imaging scanning points in a view field range; and the optical micro switch is located in front of the focus of the imaging optical assembly and comprises a plurality of sub-switches, and each sub-switch can be switched on and switched off independently. Transmission of light in a specific view field can be realized by controlling switching on and switching off of each sub-switch on the optical micro switch. The stray light feedback assembly can obtain the positions of signal light and stray light inside and outside the field of view on the optical micro switch through the switching on and switching off information of the sub-switches on the optical micro switch and the image gray scale information of different positions of the stray light feedback assembly. Transmission of the signal light and scattering of the stray light are achieved by controlling the switching on and switching off of the sub-switches at the corresponding positions on the optical micro switches. The system is simple in structural form, can accurately recognize the positions of the signal light and stray light inside and outside the field of view, and can assist in overcoming the problem that a traditional laser radar receiving optical system is difficult to suppress stray light in the field of view.

A protein free surfactant composition comprising dipalmitoylphosphatidyl choline (DPPC) and eugenol having a ratio in the range of 10:5 to 4:2 with >99% airway patency in the presence of albumin, for treating acid lung injury, adult respiratory distress syndrome and meconium aspiration syndrome.