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Compound preservative, preparation method and application thereof, blood glucose quality control liquid containing compound preservative, and preparation method and application of blood glucose quality control liquid

A technology of compounding preservatives and quality control liquids, applied in the field of medical testing, can solve problems such as unsuitable blood glucose quality control liquids, etc., and achieve the effects of good bacteriostatic effect, high-efficiency antiseptic effect, and low potential danger.

Active Publication Date: 2022-02-08
北京华益精点生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, this type of preservative is not suitable for the antiseptic work of blood sugar quality control solution

Method used

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  • Compound preservative, preparation method and application thereof, blood glucose quality control liquid containing compound preservative, and preparation method and application of blood glucose quality control liquid
  • Compound preservative, preparation method and application thereof, blood glucose quality control liquid containing compound preservative, and preparation method and application of blood glucose quality control liquid
  • Compound preservative, preparation method and application thereof, blood glucose quality control liquid containing compound preservative, and preparation method and application of blood glucose quality control liquid

Examples

Experimental program
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preparation example Construction

[0061] The present application also provides a preparation method of the above-mentioned composite preservative, which specifically includes the following steps: fully dissolving ε-polylysine, glycine, sodium benzoate, and xylitol with water or an aqueous solution to obtain a pretreatment solution; Tween-20 was fully dissolved in the pretreatment solution to obtain a composite preservative. The above compound preservatives can be used to prepare in vitro diagnostic reagent products. For example, the above compound preservatives can be used to prepare blood sugar quality control solution.

[0062] In addition, the present application provides a blood sugar quality control solution including the above-mentioned composite preservative. In terms of 100 parts by weight, the blood sugar quality control solution includes the following components by weight: 0.32-8.2 parts of a composite preservative; 0.1-8.2 parts of a thickener; 5 parts; 0.01-1 part of citric acid; 0.1-5 parts of tr...

preparation example 1-16

[0071] Preparation examples 1-16 respectively provide a composite preservative.

[0072] The difference of each preparation example lies in the addition amount of each component in its corresponding composite preservative. Specifically, the addition amount of each component in the composite preservative prepared in Preparation Examples 1-16 is shown in Table 1.

[0073] The component distribution ratio of the composite preservative that table 1 preparation example 1-16 provides

[0074]

[0075] The preparation method of above-mentioned each composite preservative is as follows:

[0076] (1) Fully dissolve the components of the composite antiseptic corresponding to each preparation example in 50mL water to obtain a pretreatment solution;

[0077] (2) Tween-20 is fully dissolved in the pretreatment solution to obtain a composite preservative.

Embodiment 1-9

[0079] Embodiments 1-9 respectively provide a blood sugar quality control solution.

[0080] The difference of each embodiment lies in the difference of compound preservatives in the blood sugar quality control solution. Specifically, the compound preservatives in the blood glucose quality control solution prepared in Examples 1-9 are shown in Table 2.

[0081] The type of compound preservative in the blood glucose quality control solution provided by table 2 embodiment 1-9

[0082] serial number Types of compound preservatives Example 1 Preparation Example 1 Example 2 Preparation example 2 Example 3 Preparation example 3 Example 4 Preparation Example 4 Example 5 Preparation Example 5 Example 6 Preparation example 6 Example 7 Preparation Example 7 Example 8 Preparation example 8 Example 9 Preparation Example 9

[0083] The preparation method of the blood glucose quality control solution provided by...

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Abstract

The invention relates to the technical field of medical detection, and particularly discloses a compound preservative, a preparation method and application thereof, a blood glucose quality control liquid containing the compound preservative, and a preparation method and application of the blood glucose quality control liquid. The compound preservative comprises the following component: epsilon-polylysine; glycine; sodium benzoate; xylitol; and tween-20. The invention further discloses a preparation method and application of the compound preservative. The blood glucose quality control liquid comprises the following components: the compound preservative; a thickening agent; citric acid; trisodium citrate; glucose; a food colorant; and water. The invention further discloses a preparation method and application of the blood glucose quality control liquid. The blood glucose quality control liquid prepared by utilizing the compound preservative provided by the invention is high in biological safety, environment-friendly, broad-spectrum, efficient and high in stability, has a relatively good preservative effect, and can ensure that glucose is not easy to degrade.

Description

technical field [0001] The present application relates to the technical field of medical detection, more specifically, it relates to a compound preservative and its preparation method and application, a blood sugar quality control solution including the compound preservative and its preparation method and application. Background technique [0002] Blood glucose testing is a routine testing item in medical testing. Blood glucose quality control solutions are commonly used in blood glucose testing projects. The role of blood glucose quality control solution is to control the quality of blood glucose testing items to ensure that the blood glucose meter and blood glucose testing test strips can operate correctly as a system. Therefore, there are high requirements for the validity of the blood glucose quality control solution assignment and the precision of repeated measurement results. Glucose is the active ingredient that mainly plays a value-assigning role in the blood gluco...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N37/46A01N37/44A01N37/10A01N43/08A01N25/30A01P1/00A01P3/00G01N1/28G01N1/38
CPCA01N37/46A01N37/44A01N37/10A01N43/08A01N25/30G01N1/28G01N1/38Y02A40/90
Inventor 汤翠红姜飞飞李泓霏陈金辉
Owner 北京华益精点生物技术有限公司
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