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A pharmaceutical composition for treating postpartum qi and blood deficiency, its preparation method and pharmaceutical preparation
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A technology of insufficient qi and blood and composition, which is applied in the field of traditional Chinese medicine and can solve problems such as unsatisfactory effects
Active Publication Date: 2018-03-23
JIANGSU KANION PHARMA CO LTD +1
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preparation example Construction
[0038] The present invention also provides a preparation method of the pharmaceutical composition, comprising the following steps:
[0039] A) In parts by weight, 10-30 parts of rehmannia glutinosa, 8-15 parts of cornus, 20-35 parts of astragalus, 10-25 parts of Atractylodes macrocephala, 8-15 parts of Chinese yam, 20-35 parts of Fangfeng and 10-35 parts of 25 parts of Ligustrum lucidum were decocted with water, and the extract was filtered and concentrated to obtain a concentrate;
[0040] B) mixing the concentrate obtained in step A) with ethanol, and concentrating under reduced pressure to obtain a pharmaceutical composition.
[0041]In the present invention, the Qiwei medicinal materials in the weight portion are preferably firstly pulverized to extract the volatile oil, and then decoct the medicinal residue after the volatile oil is extracted, and the extract is filtered and concentrated to obtain a concentrate. In the present invention, the pulverization and extraction ...
[0057] Take the above prescription medicinal materials, add 8 times the amount of purified water to decoct and extract twice, each time for 1.5 hours, filter, and combine the filtrate for later use. Add ethanol with a volume fraction of 75% and concentrate under reduced pressure (-0.05MPa, 80°C) to a relative density of 1.20 (55°C), dry under reduced pressure (75°C) to obtain a dry paste, and pulverize to obtain a pharmaceutical composition.
[0060] Take the above prescription medicinal materials, add 8 times the amount of purified water to decoct and extract twice, each time for 1.5 hours, filter, and combine the filtrate for later use. Concentrate under reduced pressure (-0.08MPa, 80°C) to a relative density of 1.22 (55°C), dry under reduced pressure (75°C) to obtain a dry paste, and grind to obtain a pharmaceutical composition.
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Abstract
The invention provides a pharmaceutical composition, comprising the following components in parts by mass: rehmannia glutinosa: 10-30 parts, cornus: 8-15 parts, astragalus: 20-35 parts, Atractylodes macrocephala: 10-25 parts, Yam: 8-15 parts, Fangfeng: 20-35 parts, Ligustrum lucidum: 10-25 parts. The present invention has carried out hemorrhagic blood deficiency experiment to mouse, and the result shows, pharmaceutical composition low, medium and high dosage group provided by the invention all can obviously improve blood RBC (red blood cell value), HGB (partial high hemoglobin concentration), and can significantly reduce the Ret value; experiments were carried out on Qi deficiency in mice caused by the starvation method, and the results showed that no matter the pharmaceutical composition of the present invention is high dose, middle dose or low dose, it can obviously prolong the Swimming time of Qi deficiency mice.
Description
technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition, a preparation method and a pharmaceutical preparation thereof. Background technique [0002] After giving birth, women often have symptoms of deficiency of Qi and blood and kidney deficiency. It is a common and relatively frequent disease in clinical practice. It is common clinically to suffer from chills, dizziness and tinnitus, palpitations, shortness of breath, withered hair, soreness of the waist and knees, etc. [0003] At present, the clinical treatment of postpartum deficiency of Qi and blood and soreness of the waist and knees is generally symptomatic treatment. Although Western medicine treatment has quick results and is easy to control the disease quickly, it has certain drug side effects and is easy to cause the disease to recur, so it is not suitable for postpartum lactating women. [0004] In order to improve thes...
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