Solid dispersion for treating peptic ulcers
A solid dispersion, peptic ulcer technology, applied in the digestive system, medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, etc. problem, to achieve the effect of improving anti-ulcer activity and improving bioavailability
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Embodiment 1
[0032] The preparation of embodiment 1 pharmaceutical composition of the present invention
[0033] Atractylodes macrocephala 10g, Poria cocos 10g, red bean 10g, astragalus 7.5g, capillary 7.5g, dandelion 7.5g, bitter almond 5g, bellflower 5g, patchouli 5g, dried ginger 2.5g, ginseng 2.5g; after drying, crush to 400 mesh , after mixing uniformly, the raw material medicine powder is obtained.
[0034] Take raw drug powder: polyethylene glycol-6000=1:1w / w, mix well, heat until polyethylene glycol-6000 is in a molten state, stir, immediately place in 0°C environment and quench until solidified, crush to obtain Solid dispersion.
Embodiment 2
[0035] The preparation of embodiment 2 pharmaceutical composition of the present invention
[0036] 180g Atractylodes macrocephala, 220g Poria cocos, 220g red bean, 170g astragalus, 170g capillary, 170g dandelion, 120g bitter almond, 120g platycodon, 120g patchouli, 60g dried ginger, 60g ginseng; after drying, crush to 400 mesh, mix well, That is, the raw material medicine powder is obtained.
[0037] Take raw drug powder: polyethylene glycol-6000=1:3w / w, mix well, heat until polyethylene glycol-6000 is in a molten state, stir, immediately place in 0°C environment and quench until solidified, crush to obtain Solid dispersion.
Embodiment 3
[0038]The preparation of embodiment 3 pharmaceutical composition of the present invention
[0039] 220g of Atractylodes macrocephala, 180g of poria cocos, 180g of red bean, 130g of astragalus, 130g of capillary, 130g of dandelion, 80g of bitter almond, 80g of bellflower, 80g of patchouli, 40g of dried ginger, 40g of ginseng; after drying, crush to 350 mesh, mix well, That is, the raw material medicine powder is obtained.
[0040] Take raw drug powder: polyethylene glycol-6000=3:1w / w, mix well, heat until polyethylene glycol-6000 is in a molten state, stir, immediately place in 0°C environment and quench until solidified, pulverize to obtain Solid dispersion.
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