An absorbable mesh reinforced interface screw and its preparation method

An interface screw and mesh technology, applied in the field of mesh-enhanced interface screws and their preparation, can solve the problems of weakening and decreasing the fixation strength of interface screws, and achieve the effects of avoiding inflammation, avoiding direct cutting, and reducing the risk of clinical use.

Active Publication Date: 2018-09-07
HANGZHOU REJOIN MASTIN MEDICAL INSTR CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The invention provides an absorbable mesh reinforced interface screw and a preparation method thereof. The technical problem to be solved by the invention is to alleviate the cavity effect and degraded particles of the composite material interface screw with polylactic acid as the matrix due to uneven degradation. Inflammatory reaction due to build-up, with attenuation of fixation strength due to cutting of tendon surface by interface screw threads

Method used

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  • An absorbable mesh reinforced interface screw and its preparation method
  • An absorbable mesh reinforced interface screw and its preparation method
  • An absorbable mesh reinforced interface screw and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] An absorbable interface screw with reticular reinforcement, which includes an absorbable interface screw and a reticular reinforcing material, the absorbable interface screw is wrapped in the reticular reinforcing material, and the absorbable interface screw consists of the following mass fraction The components are blended: 55-90% of the matrix material, 10-45% of the composite material, the matrix material is polylactic acid, the composite material is an inorganic component or an organic component, and the inorganic component is bioceramic or bioglass ; The reticular reinforcing material is blended with the following components in mass fraction: polylactic acid 50-96%, polylactic acid isomers 4-50%.

[0056] The polylactic acid is L-polylactic acid (PLLA) with a molecular weight of 200,000, the inorganic component is hydroxyapatite, and the polylactic acid isomer is racemic polylactic acid (PDLLA).

[0057] A method for preparing an absorbable mesh reinforced interfac...

Embodiment 2

[0064] An absorbable interface screw with reticular reinforcement, which includes an absorbable interface screw and a reticular reinforcing material, the absorbable interface screw is wrapped in the reticular reinforcing material, and the absorbable interface screw consists of the following mass fraction The components are blended: 80% of the matrix material, 20% of the composite material, the matrix material is polylactic acid, the composite material is an inorganic component or an organic component, and the inorganic component is bioceramic or bioglass; the mesh The shape reinforcing material is blended by the following components in mass fraction: polylactic acid 70%, polylactic acid isomer 30%.

[0065] The polylactic acid is L-polylactic acid (PLLA) with a molecular weight of 500,000, the inorganic component is hydroxyapatite, and the polylactic acid isomer is racemic polylactic acid (PDLLA).

[0066] A method for preparing an absorbable mesh reinforced interface screw, c...

Embodiment 3

[0072] 1) 75% (w / w) polylactic acid PLLA and 25% tricalcium phosphate TCP were uniformly mixed after drying, melted and blended by single-screw equipment at a temperature of 195°C, and injection-molded to obtain a polylactic acid-based interface screw;

[0073] 2) Mix 80% (w / w) polylactic acid PLLA and 20% D,L-polylactic acid PDLLA after drying, melt spinning at 225-235°C, spinning speed 7km / min, drawing The stretch ratio is 7.5. The prepared polylactic acid fibers are heat-set, cooled and solidified, and then passed through micro-weaving equipment to weave into a network structure with a mesh diameter of 0.1 μm;

[0074] 3) Molding the polylactic acid mesh into the size and shape consistent with the interface screws;

[0075] 4) The three-dimensional special-shaped mesh is heat-bonded with the interface screw through a heat-sealing process, and the heat-sealing temperature is 70° C., thereby preparing an absorbable mesh-shaped reinforced interface screw.

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Abstract

The invention relates to an absorbable reticular reinforced interface screw and a preparation method thereof. The absorbable reticular reinforced interface screw comprises an absorbable interface screw body and a reticular reinforced material, wherein the reticular reinforced material wraps the absorbable interface screw body. The absorbable interface screw body is formed by blending, by mass, 55-90% of base material and 10-45% of composite material, polylactic acid serves as the base material, the composite material consists of an inorganic matter component or organic matter component, and the inorganic matter component is biological ceramics or bioglass. The reticular reinforced material is formed by blending, by mass, 50-96% of polylactic acid and 4-50% of polylactic acid isomers. The absorbable reticular reinforced interface screw and the preparation method thereof have the advantages that a polylactic acid copolymer is prepared into a miniature reticular fabric by means of melt spinning, and the interface screw body with the polylactic acid serving as the base material is wrapped, so that own strength of the absorbable reticular reinforced interface screw is reinforced, inflammatory reaction caused by uneven degradation of an interface screw in the prior art is relieved, and decrease of interface screw fixing degree can be avoided to a certain degree.

Description

technical field [0001] The invention belongs to the technical field of orthopedic medical devices, and in particular relates to an absorbable mesh-shaped reinforced interface screw and a preparation method thereof. Background technique [0002] Anterior cruciate ligament (ACL) injury is a common injury of the knee joint, which can easily cause knee joint instability, secondary meniscus and articular cartilage damage, and affect daily life. The fixation of hamstring tendon grafts with absorbable extruded interface screws is a new and reliable approach to ACL injury, resulting in good stability of the knee joint. Compared with traditional medical metal implants, absorbable polymer materials have good biocompatibility, degradability, certain mechanical strength, and no development under magnetic resonance. Most of the existing absorbable interface screws on the market are composed of linear high molecular polymer polylactic acid (poly L-lactic acid, PLLA) and its copolymers or...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L31/12A61L31/14A61L31/10A61B17/86
Inventor 王娜楼程鸣郑炳武李斌尹雪李凌晨胡程程胡建成
Owner HANGZHOU REJOIN MASTIN MEDICAL INSTR CO LTD
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