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Medicine for treating malignant pleural effusion with syndrome of phlegm-dampness due to spleen deficiency

A technology for malignant pleural effusion, spleen deficiency and phlegm dampness, applied in the field of traditional Chinese medicine, can solve problems such as severe vomiting, aggravated symptoms, protein loss, etc.

Inactive Publication Date: 2016-02-10
QINGDAO HUAREN TECH INCUBATOR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The outstanding advantage of this method is that it can quickly relieve symptoms, but it is inevitable that some patients will lose a large amount of protein due to pumping pleural effusion, and the symptoms will aggravate; some patients will have fever and severe vomiting after intrathoracic injection of drugs.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0055] The present invention also provides a preparation method for the above-mentioned pharmaceutical granules, which includes:

[0056] The first step is to weigh rhubarb, turmeric, water gardenia, codonopsis chinensis, schisandra chinensis, cow water, platycodon root, ryepogon japonicus, scrophulariaceae, calamus calamus, psyllium seed and licorice according to the above weight, mix them together, and use an alcohol concentration of 70%~80% ethanol solution is heated and refluxed for extraction twice, the time of each extraction is 1~2 hours, the weight ratio of the ethanol solution and the Chinese medicinal materials mixed together in this step is 5~8:1, collect the extract, Filtrate, concentrate the filtrate under reduced pressure to a concentrated solution with a relative density of 1.02 to 1.06 at 60°C, put it on a macroporous adsorption resin column, and the weight of the macroporous adsorption resin is 1 to 3 times the weight of the Chinese medicinal materials mixed to...

Embodiment 1

[0060] Embodiment 1 Granule 1

[0061] Weigh 50g of rhubarb, 15g of turmeric, 40g of water gardenia, 55g of codonopsis, 40g of schisandra, 15g of beef water, 25g of platycodon, 25g of ryepogon, 20g of scrophularia, 25g of calamus, 15g of plantago and 20g of licorice, and mix them together , use 2 kg of ethanol solution with an alcohol concentration of 80% to heat and reflux to extract twice, and the time for each extraction is 2 hours, collect the extract, filter, and concentrate the filtrate under reduced pressure to 60 ° C. The relative density is a concentrated solution of 1.05, and Macroporous adsorption resin column, the weight 700g of macroporous adsorption resin, be 50%, 60% and 80% ethanol solution eluting with alcohol concentration, the volume of each described eluent is 5% of macroporous adsorption resin column volume The eluate was collected and concentrated into a clear paste with a relative density of 1.15 at 55°C. Weighed Tinglizi 20g, Guizhi 25g, Shanzi mushroom...

Embodiment 2

[0064] Embodiment 2 Granules 2

[0065] Weigh 48g of rhubarb, 13g of turmeric, 38g of water gardenia, 53g of codonopsis, 38g of schisandra, 13g of bovine water, 23g of platycodon, 23g of ryepogon, 18g of scrophulariae, 23g of calamus, 13g of psyllium and 18g of licorice, and mix them together , use 2 kg of ethanol solution with an alcohol concentration of 80% to heat and reflux to extract twice, and the time for each extraction is 2 hours, collect the extract, filter, and concentrate the filtrate under reduced pressure to 60 ° C. The relative density is a concentrated solution of 1.05, and Macroporous adsorption resin column, the weight 700g of macroporous adsorption resin, be 50%, 60% and 80% ethanol solution eluting with alcohol concentration, the volume of each described eluent is 5% of macroporous adsorption resin column volume times, collect the eluate, concentrate it into a clear paste with a relative density of 1.15 at 55°C, and weigh 18g of Tinglizi, 23g of Guizhi, 33g...

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PUM

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Abstract

The invention provides a medicine for treating malignant pleural effusion with syndrome of phlegm-dampness due to spleen deficiency. The medicine consists of the following medicinal raw materials: rheum officinale, semen lepidii, radix curcumae, cassia twig, bigflower cape jasmine fruit, pseudobulbus cremastrae seu pleiones, selfheal, codonopsis pilosula, dried ginger, schisandra chinensis, hemarthria sibirica, oriental dodartia herb, platycodon grandiflorum, radix angelicae pubescentis, herba ephedra, radix liriopes, fructus arctii, bighead atractylodes rhizome, radix scrophulariae, rhizoma acori graminei and liquorice root. The medicine, in combination with pleural infusion chemotherapy, provides an effective means for treating malignant pleural effusion, so as to relieve the reoccurrence speed of lung cancer with pleural effusion and to enhance a curative effect; in addition, in combination with traditional Chinese medicines, the medicine can relieve toxic and side effects caused by the chemotherapy and consolidate the curative effect; and meanwhile, the medicine can improve life quality and relieve clinical symptoms of a patient, and can give consideration to both the whole and the part of the patient, so as to achieve purposes of strengthening body resistance and eliminating evil.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating malignant pleural effusion of spleen deficiency and phlegm-dampness type. Background technique [0002] Malignant pleural effusion refers to pleural effusion caused by malignant tumor involving the pleura or primary pleural tumor. It is one of the common complications of malignant tumors in the late stage, and the incidence rate accounts for about 25% of pleural effusions. Malignant tumors that cause malignant pleural effusions include lung cancer, breast cancer, and lymphoma. Clinically, it can cause symptoms such as chest pain and dyspnea, and even respiratory failure, which seriously affects the quality of life of patients and shortens the survival time of patients. Some studies have shown that the survival time is generally less than 6 months. The rapid growth of malignant pleural effusion can cause compressive atelectasis and res...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P35/00A61P7/10A61K35/48
Inventor 不公告发明人
Owner QINGDAO HUAREN TECH INCUBATOR
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