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Kidney benefiting and yang tonifying capsule and preparing method thereof

A technology for kidney yang and impotence, applied in the field of traditional Chinese medicine, can solve the problems of slow disintegration, unsatisfactory curative effect, and low curative effect

Inactive Publication Date: 2016-02-24
HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commercially available Yishen Xingyang Capsules have unsatisfactory curative effect due to the composition and process. The preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect.

Method used

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  • Kidney benefiting and yang tonifying capsule and preparing method thereof
  • Kidney benefiting and yang tonifying capsule and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take 3.7g of vitex, 7.4g of geranium, 37g of salsa, 5g of antler, 14.8g of cistanche, 25g of dodder, 22.2g of ginseng, 25g of astragalus, grind them into 60 mesh coarse powder, and extract them by supercritical carbon dioxide extraction. The extraction pressure is 17Mpa, the extraction temperature is 16°C, the separator pressure is 10Mpa, the separator temperature is 42°C, the separation time is 1.7 hours, the carbon dioxide flow rate is 25L per hour, and the extract is obtained; the extract is dried under reduced pressure at 61°C to obtain a dry paste; Add 150g of mannitol to the paste, and use a high-energy nano-impact mill to pulverize it into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 45g of microcrystalline cellulose, 45g of cross-linked polyvinylpyrrolidone, and 45g of cross-linked carboxymethyl cellulose Sodium 35g, mix well, wet granulate with 50% ethanol, dry at 60°C, add 7g sodium carboxymethyl starch, 1g magnes...

specific Embodiment 2

[0028] Take 3.7g of vitex, 7.4g of geranium, 37g of salsa, 5g of antler, 14.8g of cistanche, 25g of dodder, 22.2g of ginseng, 25g of astragalus, grind them into 60 mesh coarse powder, and extract them by supercritical carbon dioxide extraction. The extraction pressure is 35Mpa, the extraction temperature is 41°C, the separator pressure is 19Mpa, the separator temperature is 52°C, the separation time is 3.6 hours, the carbon dioxide flow rate is 40L per hour, and the extract is obtained; the extract is dried under reduced pressure at 76°C to obtain a dry paste; Add 200g of mannitol to the paste, and use a high-energy nano-impact mill to pulverize it into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 55g of microcrystalline cellulose, 55g of cross-linked polyvinylpyrrolidone, and 55g of cross-linked carboxymethyl cellulose Sodium 45g, mix well, wet granulate with 70% ethanol, dry at 80°C, add 9g sodium carboxymethyl starch, 3g magnes...

Embodiment 3

[0030] Take 3.7g of vitex, 7.4g of geranium, 37g of salsa, 5g of antler, 14.8g of cistanche, 25g of dodder, 22.2g of ginseng, 25g of astragalus, grind them into 60 mesh coarse powder, and extract them by supercritical carbon dioxide extraction. The extraction pressure is 26Mpa, the extraction temperature is 29°C, the separator pressure is 15Mpa, the separator temperature is 47°C, the separation time is 2.7 hours, the carbon dioxide flow rate is 33L per hour, and the extract is obtained; the extract is dried under reduced pressure at 68°C to obtain a dry paste; Add 175g of mannitol to the paste, and use a high-energy nano-impact mill to pulverize it into a mixed dry paste powder with a particle size of 200-300nm; take the mixed dry paste powder, 50g of microcrystalline cellulose, 50g of cross-linked polyvinylpyrrolidone, and 50g of cross-linked carboxymethyl cellulose Sodium 40g, mix well, wet granulate with 60% ethanol, dry at 70°C, add 8g sodium carboxymethyl starch, 2g magnes...

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Abstract

The invention discloses a kidney benefiting and yang tonifying capsule and a preparing method thereof. The preparing method is characterized by including the steps that 3.7 g of chastetree fruits, 7.4 g of geranium wilfordii, 37 g of Chinese buckeye seeds, 5 g of cornu cervi pantotrichum, 14.8 g of desertliving cistanche, 25 g of semen cuscutae, 22.2 g of ginseng and 25 g of astragalus membranaceus are taken, extracting is carried out with a carbon dioxide supercritical extraction method, pressure reducing and drying are carried out, the mixture is smashed into dry nanometer cream through a high-energy nanometer impacting grinder, functional auxiliary materials are added, and the kidney benefiting and yang tonifying capsule is prepared. The disintegration time is remarkably shortened, the curative effect of the kidney benefiting and yang tonifying capsule is remarkably better than that of a kidney benefiting and yang tonifying capsule sold in a market, and the positive effect is achieved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a Yishen Xingyang capsule and a preparation method thereof. Background technique [0002] Yishen Xingyang Capsule tonifies kidney and Qi, strengthens yang and solidifies essence. It is used for sore waist and weak legs, mental fatigue, dizziness and tinnitus, insomnia, forgetfulness, impotence, nocturnal emission and premature ejaculation caused by kidney yang deficiency and qi deficiency. Commercially available Yishen Xingyang Capsules have unsatisfactory curative effect due to the composition and process, and the preparation is prepared by traditional technology, which has the disadvantages of slow disintegration and low curative effect. Contents of the invention [0003] In order to overcome the above disadvantages, the present invention provides a Yishen Xingyang capsule with fast disintegration speed and high curative effect and a preparation method thereof. ...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61K9/48A61P13/12A61P1/08A61P27/16A61P25/28A61P15/08
CPCA61K36/85A61K9/1652A61K35/32A61K36/185A61K36/258A61K36/39A61K36/481A61K36/64A61K47/10A61K47/12A61K47/32A61K47/36A61K47/38A61K2236/37A61K2236/51
Inventor 不公告发明人
Owner HEILONGJIANG JIANGHENG PHARMA TECH CO LTD
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