Baohou tablets and preparation method thereof
A technology for tablet compression and yin-deficiency sore throat, applied in the field of Baohou Tablets and its preparation, can solve the problems of slow disintegration, unsatisfactory curative effect, and low curative effect
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Embodiment 1
[0037] Take 44g of geranium, 88g of sala seed, 17.6g of nutmeg, 8.8g of peylan, 52g of black plum, 26g of myrobalan (pitted), 40g of bellflower, 26g of trichosanthes, 64g of licorice, 22g of perilla stalk, 0.65g of wheat Winter 2.6g, Codonopsis 64g, Scrophulariaceae 64g, Silkworm 28g, crushed into 60-mesh coarse powder, extracted by supercritical carbon dioxide extraction method, extraction pressure 24Mpa, extraction temperature 15°C, separator pressure 10Mpa, separator temperature 37°C, The separation time is 2.1 hours, and the carbon dioxide flow rate is 21L per hour to obtain the extract; take the extract and dry it under reduced pressure at 61°C to obtain a dry paste; add 80g of citric acid to the dry paste, and use a high-energy nano-impact mill to pulverize it into a particle size of 200-300nm Mix dry cream powder; take mixed dry cream powder, microcrystalline cellulose 35g, hydroxypropyl cellulose 35g, croscarmellose sodium 35g, magnesium aluminum silicate 15g, sodium ch...
specific Embodiment 2
[0039]Take 44g of geranium, 88g of sala seed, 17.6g of nutmeg, 8.8g of peylan, 52g of black plum, 26g of myrobalan (pitted), 40g of bellflower, 26g of trichosanthes, 64g of licorice, 22g of perilla stalk, 0.65g of wheat Winter 2.6g, Codonopsis 64g, Scrophulariaceae 64g, Silkworm 28g, crushed into 60-mesh coarse powder, extracted by carbon dioxide supercritical extraction method, extraction pressure 42Mpa, extraction temperature 45°C, separator pressure 18Mpa, separator temperature 53°C, The separation time was 3.7 hours, and the flow rate of carbon dioxide was 39L per hour to obtain the extract; the extract was dried under reduced pressure at 80°C to obtain a dry paste; Mix dry cream powder; take mixed dry cream powder, microcrystalline cellulose 45g, hydroxypropyl cellulose 45g, croscarmellose sodium 45g, magnesium aluminum silicate 25g, sodium chloride 15g, mannitol 6g, malt paste 6g of essence, mixed evenly, wet granulated with 70% ethanol, dried at 80°C, added 9g of sodium...
Embodiment 3
[0041] Take 44g of geranium, 88g of sala seed, 17.6g of nutmeg, 8.8g of peylan, 52g of black plum, 26g of myrobalan (pitted), 40g of bellflower, 26g of trichosanthes, 64g of licorice, 22g of perilla stalk, 0.65g of wheat Winter 2.6g, Codonopsis 64g, Scrophulariaceae 64g, Silkworm 28g, crushed into 60-mesh coarse powder, extracted by carbon dioxide supercritical extraction, extraction pressure 33Mpa, extraction temperature 30°C, separator pressure 14Mpa, separator temperature 45°C, The separation time is 2.9 hours, and the carbon dioxide flow rate is 30L per hour to obtain the extract; take the extract and dry it under reduced pressure at 70°C to obtain a dry paste; add 100g of citric acid to the dry paste, and use a high-energy nano-impact mill to pulverize it into a particle size of 200-300nm Mix dry cream powder; take mixed dry cream powder, microcrystalline cellulose 40g, hydroxypropyl cellulose 40g, croscarmellose sodium 40g, magnesium aluminum silicate 20g, sodium chloride...
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