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Pharmaceutical composition for post-operative nursing for cholangitis and preparation method of pharmaceutical composition

A composition and a technology for cholangitis, applied in the field of postoperative care medication, can solve the problems of inability to resist the side effects of antibiotics and poor body resistance, and achieve the effects of regulating human immune function, enhancing nutrition, and simple preparation process

Inactive Publication Date: 2016-05-18
李萍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Nursing care after surgical treatment is also very important, not only to eliminate infection, but also to prevent the recurrence of cholangitis from various aspects. The combined application of large doses of broad-spectrum antibiotics is very important to control infection before surgery, but postoperative The body's resistance is poor, the body is weak, and cannot resist the side effects of a large number of antibiotics. Therefore, a drug is needed in the postoperative care of cholangitis that can not only effectively antibacterial and anti-inflammatory, but also promote the recovery of the body and prevent the recurrence of bile duct inflammation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A tablet of a pharmaceutical composition for postoperative care of cholangitis, mainly composed of the following ingredients in parts by weight: 12 parts of p-coumaric acid, 15 parts of naringin, 10 parts of lotusin, and water shield extract 10 parts, 15 parts of mangoside, 8 parts of red stone resin nanopowder, 12 parts of limonene, 16 parts of eucalyptol, 14 parts of chlorogenic acid, 6 parts of levamisole hydrochloride, 20 parts of magnesium sulfate solution, 50 parts of corn steep liquor, sorbic acid 8 parts of potassium acid potassium, 13 parts of mixed amino acids; also includes auxiliary materials: 18 parts of lubricants, 26 parts of disintegrants.

[0018] Wherein, the preparation method of the water shield extract is as follows: fresh water shield is cleaned and crushed, placed in a flash extractor, and 5 times the amount of ethanol solution with a mass concentration of 55% is added for flash extraction, and the obtained After the extract was left to stand for ...

Embodiment 2

[0024] A tablet of a pharmaceutical composition for postoperative care of cholangitis, mainly composed of the following ingredients in parts by weight: 21 parts of p-coumaric acid, 23.5 parts of naringin, 19 parts of lotusin, and water shield extract 17.5 parts, 20.5 parts of mangoside, 13 parts of red stone resin nanopowder, 18 parts of limonene, 22 parts of eucalyptol, 17 parts of chlorogenic acid, 9 parts of levamisole hydrochloride, 30 parts of magnesium sulfate solution, 75 parts of corn steep liquor, sorbic acid Potassium acid 12 parts, mixed amino acid 19 parts.

[0025] Wherein, the preparation method of the water shield extract is as follows: fresh water shield is cleaned and pulverized, placed in a flash extractor, 6.5 times the mass concentration of 60% ethanol solution is added for flash extraction, and the obtained After the extract was left to stand for 10 hours, it was filtered through a macroporous adsorption resin, and the filtrate was concentrated under reduc...

Embodiment 3

[0031] A tablet of a pharmaceutical composition for postoperative care of cholangitis, mainly composed of the following ingredients in parts by weight: 30 parts of p-coumaric acid, 32 parts of naringin, 28 parts of lotusin, and water shield extract 25 parts, 26 parts of mangoside, 18 parts of red stone resin nanopowder, 24 parts of limonene, 28 parts of eucalyptol, 20 parts of chlorogenic acid, 12 parts of levamisole hydrochloride, 40 parts of magnesium sulfate solution, 100 parts of corn steep liquor, sorbic acid Potassium acid 16 parts, mixed amino acid 25 parts.

[0032] Wherein, the preparation method of the water shield extract is as follows: fresh water shield is cleaned and pulverized, placed in a flash extractor, and 8 times the amount of ethanol solution with a mass concentration of 65% is added for flash extraction, and the obtained After the extract was left to stand for 12 hours, it was filtered through a macroporous adsorption resin, and the filtrate was concentra...

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PUM

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Abstract

The invention discloses pharmaceutical composition for post-operative nursing for cholangitis and a preparation method of the pharmaceutical composition. The pharmaceutical composition for post-operative nursing for the cholangitis comprises components in parts by weight as follows: 12-30 parts of p-coumaric acid, 15-32 parts of naringin, 10-28 parts of cordacin, 10-25 parts of a water shield extract, 15-26 parts of mangiferin, 8-18 parts of red halloysite nano-powder, 12-24 parts of limonene, 16-28 parts of eucalyptol, 14-20 parts of chlorogenic acid, 6-12 parts of levamisole hydrochloride, 40-80 parts of a magnesium sulfate solution, 50-100 parts of corn steep liquor, 8-16 parts of potassium sorbate and 13-25 parts of mixed amino acid. Effective components of Chinese herbal medicines are added on the basis of Western medicines, the pharmaceutical composition has effects of resisting bacteria, diminishing inflammations, inhibiting intestinal infection and preventing cholestasis, effectively regulates functions of the liver, the gall bladder and intestines of a patient and improves various anomaly indexes of the body, so that relapse of the cholangitis is prevented, and post-operative body recovery of the patient can be accelerated. The pharmaceutical composition is simple in preparation process and convenient to use and has the great clinical significance.

Description

technical field [0001] The invention relates to the technical field of postoperative nursing medicine, in particular to a pharmaceutical composition for postoperative nursing of cholangitis and a preparation method thereof. Background technique [0002] Cholangitis is a biliary tract inflammation mainly caused by bile duct inflammation. Most of them are secondary bacterial infections caused by cholestasis. The pathogenic bacteria are mainly Gram-negative bacilli, and the most common one is Escherichia coli. Bacteria pass through the lymphatic or The blood channel reaches the biliary tract, and can also enter the biliary tract retrogradely from the intestinal tract through the duodenal papilla. It is mainly divided into acute cholangitis and chronic cholangitis. The clinical symptoms are manifested as upper abdominal discomfort, distending pain, or colic attack. After eating greasy food, upper abdominal pain can be aggravated. Fever and jaundice are rarely seen, and abdominal...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P1/16A61K31/015A61K31/192A61K31/198A61K31/216A61K31/352A61K31/429A61K31/7048A61K33/06A61K33/26
CPCA61K31/192A61K9/2013A61K31/015A61K31/198A61K31/216A61K31/352A61K31/429A61K31/7048A61K33/06A61K33/26A61K36/36A61K36/61A61K36/62A61K36/899A61K2236/333A61K2236/51A61K2236/55A61K2300/00
Inventor 李萍
Owner 李萍
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