The invention discloses a Zr-Nb-based alloy with good additive manufacturing forming performance and application of the Zr-Nb-based alloy, and belongs to the technical field of metal additive manufacturing. Components of the Zr-Nb-based alloy are from a dual cluster alloy component design model. The expression formula of the alloy element atomic percent (at./%) is Zr75+/-2(Zr, Mo, Sn)3.1+/-0.5(Zr,Ti, Hf, Nb, Ta)21.9+/-1.5, wherein (Zr, Ti, Hf, Nb, Ta) elements are single, or the mixed total quantity is 21.9+/-1.5 at./%, (Zr, Mo, Sn) elements are single, or the mixed total quantity is 3.1+/-0.5 at./%, and the total quantity of the other elements is controlled within 1 at.%. The main alloying element of the alloy is the Nb element; the low-elasticity-modulus Nb element has low magnetic susceptibility; meanwhile, grains of the alloy can be refined; the oxidization resistance of alloy melt and melt stability are improved; liquid-solid phase areas are reduced; flowability is enhanced; andthe alloy has good melt and solid structure compatibility and can be used for additive manufacturing forming.