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In vivo absorbable metal staple and preparation method thereof

A staple and metal technology, which is applied to the field of absorbable metal staples in vivo and their preparation, can solve the problems that the mechanical properties and biocompatibility requirements of staples cannot be met at the same time, and large-scale practical clinical applications cannot be obtained. Achieve the effect of ensuring biosafety and good biocompatibility

Active Publication Date: 2017-08-15
SUZHOU ORIGIN MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, the above-mentioned patents cannot meet the performance requirements of staples in terms of mechanical properties and biocompatibility at the same time, so that large-scale practical clinical applications cannot be obtained.

Method used

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  • In vivo absorbable metal staple and preparation method thereof
  • In vivo absorbable metal staple and preparation method thereof
  • In vivo absorbable metal staple and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Under a protective atmosphere (the volume ratio of sulfur hexafluoride is 3%, the volume ratio of argon is 30%, and the rest is carbon dioxide), melt pure magnesium in a crucible at 750°C, and add 3.5% Zn, 0.5% Ca, 0.4% Fe and 3.3% Mn are cast into alloy ingots after being stirred and kept warm; put the alloy ingots into a heat treatment furnace, and perform homogenization treatment at 355°C for 12 hours; the alloy ingots after homogenization treatment are directly processed Hot extrusion, the extrusion ratio is 17, and the extrusion temperature is 250°C to obtain the primary billet; the primary billet is cut and turned to obtain the billet, and then quenched after solution treatment at 300°C for 8 hours to form the secondary billet ; Multi-pass continuous drawing of the secondary blank to form wires of different diameters. Wherein, in-situ oxygen-free annealing is performed when the cross-sectional area reduction rate is 40%, the annealing temperature is 200° C., and t...

Embodiment 2

[0026] Under a protective atmosphere (the volume ratio of sulfur hexafluoride is 3%, the volume ratio of argon is 30%, and the rest is carbon dioxide), melt pure magnesium in a crucible at 750°C, and add 2.2% Zn, 0.2% Ca, 0.3% Fe and 3% Mn are cast into alloy ingots after being stirred and kept warm; put the alloy ingots into a heat treatment furnace, and perform homogenization treatment at 355°C for 12 hours; the alloy ingots after homogenization treatment are directly processed Hot extrusion, the extrusion ratio is 17, and the extrusion temperature is 250°C to obtain the primary billet; the primary billet is cut and turned to obtain the billet, and then quenched after solution treatment at 300°C for 8 hours to form the secondary billet ; Multi-pass continuous drawing of the secondary blank to form wires of different diameters. Wherein, in-situ oxygen-free annealing is performed when the cross-sectional area reduction rate is 40%, the annealing temperature is 200° C., and the...

Embodiment 3

[0028] Under a protective atmosphere (the volume ratio of sulfur hexafluoride is 3%, the volume ratio of argon is 30%, and the rest is carbon dioxide), melt pure magnesium in a crucible at 750°C, and add 3.7% Zn, 0.7% Ca, 0.5% Fe and 4% Mn, after being stirred and kept warm, cast into alloy ingots; put the alloy ingots into a heat treatment furnace, and perform homogenization treatment at 355°C for 12 hours; the alloy ingots after homogenization treatment are directly processed Hot extrusion, the extrusion ratio is 17, and the extrusion temperature is 250°C to obtain the primary billet; the primary billet is cut and turned to obtain the billet, and then quenched after solution treatment at 300°C for 8 hours to form the secondary billet ; Multi-pass continuous drawing of the secondary blank to form wires of different diameters. Wherein, in-situ oxygen-free annealing is performed when the cross-sectional area reduction rate is 40%, the annealing temperature is 200° C., and the a...

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Abstract

The invention relates to a device in the technical filed of medical apparatus and instruments, in particular to an in-vivo absorbable metal surgical staple and a preparation method thereof. The surgical staple is made of a magnesium alloy, the length of a staple body is 3.0-20.0 mm, and the length of a staple leg is 3.0-20.0 mm. The magnesium alloy sequentially comprises components in percentage by mass as follows; 2.0-5.8% of Zn, 0.2%-0.7% of Ca, 0.3%-0.5% of Fe, 3%-4% of Mn and the balance of Mg.

Description

technical field [0001] The invention relates to a device in the technical field of medical devices, in particular to an in vivo absorbable metal staple and a preparation method thereof. Background technique [0002] Staples are medical devices currently used in clinical medicine to replace traditional manual sutures. They are easy to use, fast to suture during surgery, and easy to operate. They can significantly shorten tissue exposure time, reduce trauma and bleeding, and effectively reduce surgical complications. The staple materials currently used in clinical practice mainly include stainless steel, titanium and titanium alloys. These metal materials are all inert materials and cannot be degraded in the human body, so the staples will permanently exist as foreign objects in the human body, slowly releasing debris and even toxic and irritating ions, causing severe inflammatory reactions in the surrounding tissues, reducing the Device biocompatibility and safety. If the s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B17/064A61L31/02A61L31/14C22C23/04C22C23/00C22C1/02C22F1/06
CPCA61B17/064A61L31/022A61L31/148C22C1/02C22C23/00C22C23/04C22F1/06
Inventor 张绍翔刘静怡张元壮姜曼赵常利张小农
Owner SUZHOU ORIGIN MEDICAL TECH
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