Preparation technology of tylosin tartrate premix based on uniform mixing effect improvement

Abstract

The invention discloses a preparation technology of a tylosin tartrate premix based on uniform mixing effect improvement. The preparation technology includes the steps of 1), extracting tylosin tartrate, namely adopting trichloromethane for extracting reextraction liquid containing the tylosin tartrate, and subjecting the trichloromethane extraction liquid to anhydrous sodium sulfate to dehydration and reduced pressure distillation to remove the trichloromethane completely so as to obtain tylosin tartrate; 2) drying the extracted tylosin tartrate and preparing the dried tylosin tartrate into powder; 3) preparing the tylosin tartrate premix by uniformly mixing the tylosin tartrate powder with minor ingredients through a mixing device, and bagging according to specifications. The preparation technology of the tylosin tartrate premix based on uniform mixing effect improvement has the advantages that since a V-shaped feeding port allowing simultaneous addition of two different raw materials is arranged, the fed raw materials pass through a primary mixing chamber and a secondary mixing chamber sequentially to be subjected to two-time mixing, and accordingly raw material mixing uniformity is improved, the uniformly-mixed raw materials are discharged out of a discharging port, and continuous uniform mixing and outputting of active pharmaceutical ingredients are achieved.

Description

technical field [0001] The invention relates to the field of preparation technology of medical drugs, in particular to a preparation technology of tylosin tartrate premix based on improving the mixing effect. Background technique [0002] Tylosin tartrate and Tylosin tartrate have special effects on mycoplasma and are used as the first choice for anti-mycoplasma disease. Tylosin tartrate belongs to macrolide antibiotics for animals. Its mechanism of action mainly plays a sterilizing effect by hindering the synthesis of bacterial protein. This product is easily absorbed in the body, excreted quickly, and remains in the tissue. It has special effects on Gram-positive bacteria and mycoplasma. In particular, it has very high activity against Actinobacillus pleurisy, and is the drug of choice for the treatment of chronic respiratory diseases in livestock and poultry caused by mycoplasma. [0003] How to improve the effect and safety of drug injections has always been a problem ...

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide the preparation technology based on the tylosin tartrate premix that improves mixing effect, solve the preparation technology of existing tylosin tartrate premix that easily leads to the problem of tylosin tartrate premix The problem of slow production speed and uneven mixing

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