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Preparation method of tylosin tartrate premix

A technology of tylosin tartrate and premix is ​​applied in chemical instruments and methods, medical preparations containing active ingredients, mixers, etc., and can solve the problems of slow production speed of tylosin tartrate premix, etc., Achieve the effect of solving the slow production speed and improving the uniformity

Inactive Publication Date: 2016-08-17
CHINA CHENGDU ANIMAL HUSBANDRY IND BIOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide the preparation method of tylosin tartrate premix, solve the preparation technology of existing tylosin tartrate premix which easily causes the production speed of tylosin tartrate premix to be relatively slow

Method used

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  • Preparation method of tylosin tartrate premix

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Such as figure 1 Shown, the preparation method of tylosin tartrate premix comprises the following steps:

[0033] 1) Extraction of tylosin tartrate: using chloroform to extract back extraction containing tylosin tartrate

[0034] Take the liquid, dehydrate the extract of chloroform with anhydrous sodium sulfate successively, and distill under reduced pressure to remove the chloroform to obtain tylosin tartrate;

[0035] 2) Dry the extracted tylosin tartrate and prepare it into powder;

[0036] 3) Preparation process of tylosin tartrate premix: mix tylosin tartrate powder with auxiliary materials

[0037] After uniform mixing by the mixing device, bagging is carried out according to the specifications. The mixing device includes a V-shaped feed port 1, and the discharge end of the V-shaped feed port 1 is connected with a primary mixing chamber 2. The primary mixing chamber 2 is provided with a first rotating shaft 3, a protrusion 31 is arranged on the first rotating s...

Embodiment 2

[0039] Such as figure 1 As shown, this embodiment is based on Embodiment 1, and the protrusion 31 is a smooth conical structure, and the circle

[0040] The apex of the cone structure is away from the first rotating shaft 3; the spiral structure 51 is a smooth tubular body. The bottom of the secondary mixing chamber 4 is sunken downwards, and a groove is formed in the middle, and the discharge port 6 is arranged at the groove; the bottom of the support seat 8 is covered with a protective cover 9 .

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Abstract

The invention discloses a preparation method of a tylosin tartrate premix. The method comprises the following steps: 1, extracting tylosin tartrate: extracting a tylosin tartrate-containing back extraction solution with trichloromethane, dehydrating the obtained trichloromethane extract solution through using anhydrous sodium sulfate, and carrying out reduced pressure distillation to completely remove trichloromethane in order to obtain tylosin tartrate; 2, drying the extracted tylosin tartrate, and processing the dried tylosin tartrate to obtain powder; and 3, preparing the tylosin tartrate premix: uniformly mixing the tylosin tartrate powder with auxiliary materials through a mixing device, and packaging the obtained premix in bags by specification. The problem of slow production speed of the tylosin tartrate premix, easily induced by present preparation technologies of the tylosin tartrate premix, is solved in the invention.

Description

technical field [0001] The invention relates to the field of preparation technology of medical drugs, in particular to a preparation method of tylosin tartrate premix. Background technique [0002] Tylosin tartrate and Tylosin tartrate have special effects on mycoplasma and are used as the first choice for anti-mycoplasma disease. Tylosin tartrate belongs to macrolide antibiotics for animals. Its mechanism of action mainly plays a sterilizing effect by hindering the synthesis of bacterial protein. This product is easily absorbed in the body, excreted quickly, and remains in the tissue. It has special effects on Gram-positive bacteria and mycoplasma. In particular, it has very high activity against Actinobacillus pleurisy, and is the drug of choice for the treatment of chronic respiratory diseases in livestock and poultry caused by mycoplasma. [0003] How to improve the effect and safety of drug injections has always been a problem that drug manufacturers hope to solve. Th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K31/7048A61P31/04B01F7/02B01F7/06B01F27/71
CPCA61K9/14A61K31/7048B01F27/2322B01F27/60B01F27/71B01F2101/22
Inventor 卢朝成廖成斌
Owner CHINA CHENGDU ANIMAL HUSBANDRY IND BIOPHARM
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