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Component for nasopharynx moisture preserving and preparing method thereof

A nasopharyngeal and compound technology, used in drug combinations, respiratory diseases, etc., can solve the problems of easy flow into other organs, short moisturizing time, and increase the cost of use, so as to reduce the risk of mucosal irritation and infection, and shield allergic substances and bacteria. , the effect of reducing the risk of infection

Inactive Publication Date: 2016-06-22
张巍
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] 1. The essence is an ionic aqueous solution with low viscosity and high fluidity. If the baby's head is tilted back during use, it will easily flow into other organs, which may cause danger;
[0004] 2. Due to the low viscosity of the solution and the lack of water retention, the continuous moisturizing time after use is too short. Frequent spraying by the user will cause the local ion concentration to be too high and the cells will lose water, which will aggravate the symptoms of dry itching of the mucosa , which increases the user's use cost and brings a lot of inconvenience to life;
[0005] 3. Too much emphasis is placed on antibacterial and anti-inflammatory effects while ignoring the antipruritic effect. Foreign research data show that it is easier to recover skin surface wounds in a humid environment, and too many such products emphasize the use of metal ions to intervene in the microenvironment of the wound , which will affect normal human body functions, reduce the immunity of mucosal tissues, and also cause a waste of resources
[0006] Physiological seawater is an ionic solution. Although it can temporarily relieve discomfort symptoms such as dryness and itching on the surface of the nasopharyngeal mucosa, due to the particularity of its nasal cavity structure, the air flow on the surface of the nasal cavity is violent, and the surface water evaporates quickly. At the same time, physiological seawater does not yet have Humidity and water-locking properties are relatively weak, so patients need to spray frequently, which brings many restrictions during use and increases the cost of use for patients

Method used

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  • Component for nasopharynx moisture preserving and preparing method thereof
  • Component for nasopharynx moisture preserving and preparing method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] A preparation method of a component used for nasopharynx moisturizing, the following steps are completed in a 100-grade purification workshop under GMP conditions:

[0032] Step 1: Mix 1 part of sodium alginate, 10 parts of sodium carboxymethylcellulose, 0.1 part of peppermint essence and 0.1 part of potassium sorbate with water in a mixing tank and stir for 1 hour to dissolve the above substances to form a viscous Transparent solution A;

[0033] Step 2: The transparent liquid A was left to stand for 3 hours for defoaming to obtain a solution B;

[0034] Step 3: filter the solution B to remove insoluble matter and bacteria in the solution to obtain solution C;

[0035] Step 4: filling the solution C.

Embodiment 2

[0037] A preparation method of a component used for nasopharynx moisturizing, the following steps are completed in a 100-grade purification workshop under GMP conditions:

[0038] Step 1: Mix 10 parts of sodium alginate, 30 parts of sodium carboxymethylcellulose, 3 parts of peppermint essence and 6 parts of potassium sorbate with water in a mixing tank and stir for 5 hours to dissolve the above substances to form a viscous Transparent solution A;

[0039] Step 2: leave the transparent liquid A for 10 hours to defoam, and obtain solution B;

[0040] Step 3: Filter the solution B to remove insoluble matter and bacteria in the solution to obtain solution C.

Embodiment 3

[0042] A preparation method of a component used for nasopharynx moisturizing, the following steps are completed in a 100-grade purification workshop under GMP conditions:

[0043] Step 1: Mix 1 part of sodium alginate, 30 parts of sodium carboxymethyl cellulose, 0.1 part of peppermint essence and 0.1 part of potassium sorbate with water in a mixing tank and stir for 1 hour to dissolve the above substances to form a viscous Transparent solution A;

[0044] Step 2: The transparent liquid A was left to stand for 3 hours for defoaming to obtain a solution B;

[0045] Step 3: Filter the solution B to remove insoluble matter and bacteria in the solution to obtain solution C.

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Abstract

The invention discloses a component for moisturizing the nasopharynx and a preparation method thereof, belonging to the technical field of nasopharyngeal medicaments. Firstly, put alginic acid compound and carboxymethyl cellulose compound in a mixing tank, and add essence or auxiliary agent , mixed with water and stirred to dissolve the above substances to form a transparent solution with viscosity, and then stand for defoaming until the two macromolecules of alginic acid compound and carboxymethyl cellulose compound in the solution are fully expanded, and the intermolecular forces A microscopic three-dimensional network structure is formed under the action of the filter. On the one hand, the product of the present invention obtained after filtration has water retention properties; And the risk of infection, no need to add ionic antibacterial agents, save resources, reduce costs, and prevent the normal immune system from being disturbed. By scientifically adjusting the ratio of the two macromolecules, the fluidity, coverage and durability of the product prepared by the present invention can all reach the best state.

Description

technical field [0001] The invention belongs to the technical field of nasopharyngeal medicaments, in particular to a component for moisturizing nasopharynx and a preparation method thereof. Background technique [0002] With the acceleration of people's life rhythm and the continuous aggravation of environmental pollution, people tend to experience various physical discomforts, among which dry nasopharynx is more common. Nasopharyngeal dryness is a symptom of physical discomfort caused by a variety of reasons, which can be mainly divided into two reasons: climate, environmental reasons and pathological changes of nasopharyngeal tissue. In spring and autumn, the weather is dry and windy, and the body loses more water. Most people will experience dryness in the nasopharynx. The pollutants in the environment often contain some pollutants and irritating substances. Low immunity often leads to dryness of the nasal cavity and oral mucosa surface, which generally does not affect ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/734A61K31/717A61P11/02A61P11/04
CPCA61K31/734A61K31/717
Inventor 张巍
Owner 张巍
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