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Healthcare tablets capable of increasing bone mineral density and preparation method and application thereof

A technology for increasing bone density and health care tablets, which can be used in medical preparations containing active ingredients, bone diseases, pharmaceutical formulations, etc. The effect of easy fracture symptoms, low production cost and simple production process

Inactive Publication Date: 2016-06-22
SHANDONG WUZHOU DETECTION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, many studies have shown that the use of estrogen replacement therapy can significantly increase the incidence of endometrial cancer and breast cancer, so it is not a very ideal treatment method

Method used

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  • Healthcare tablets capable of increasing bone mineral density and preparation method and application thereof
  • Healthcare tablets capable of increasing bone mineral density and preparation method and application thereof
  • Healthcare tablets capable of increasing bone mineral density and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] In the embodiment of the present invention, a health-care tablet for increasing bone density is composed of the following raw materials in parts by weight: 18 parts of longli leaves, 3 parts of spider incense, and 20 parts of tangerine peel.

[0024] After drying Longli leaves and spider incense, they were respectively crushed through a 100-mesh sieve, weighed according to the weight and then mixed and sent to the extraction kettle for subcritical extraction to obtain an extract; wherein the extraction solvent was carbon dioxide, and the ratio of solvent to material was 2.8:1, and add an appropriate amount of edible alcohol as an entrainer. The subcritical extraction conditions are: extraction temperature 28°C, extraction pressure 0.3MPa, cyclic extraction for 70min, and extraction solvent flow rate of 35L / h. Crush the orange peel, pass through a 100-mesh sieve, add deionized water 6 times the weight of the orange peel, heat to 45° C. and stir for 20 minutes to obtain a ...

Embodiment 2

[0026] In the embodiment of the present invention, a health-care tablet for increasing bone density is composed of the following raw materials in parts by weight: 28 parts of longli leaves, 10 parts of spider incense, and 32 parts of tangerine peel.

[0027] After drying Longli leaves and spider incense, they were respectively crushed through a 200-mesh sieve, weighed according to parts of weight, mixed and sent to an extraction kettle for subcritical extraction to obtain an extract; wherein the extraction solvent was carbon dioxide, and the ratio of solvent to material was 3.2:1, and add an appropriate amount of edible alcohol as an entrainer. The subcritical extraction conditions are: extraction temperature 35°C, extraction pressure 0.5MPa, cyclic extraction for 90min, and extraction solvent flow rate of 38L / h. Crush the orange peel, pass through a 200-mesh sieve, add deionized water 8 times the weight of the orange peel, heat to 50° C. and stir for 30 minutes to obtain a mix...

Embodiment 3

[0029] In the embodiment of the present invention, a health-care tablet for increasing bone density is composed of the following raw materials in parts by weight: 20 parts of longli leaves, 5 parts of spider incense, and 23 parts of tangerine peel.

[0030] After drying Longli leaves and spider incense, they were respectively crushed through a 200-mesh sieve, weighed according to parts of weight, mixed and sent to an extraction kettle for subcritical extraction to obtain an extract; wherein the extraction solvent was carbon dioxide, and the ratio of solvent to material was 3:1, and add an appropriate amount of edible alcohol as an entrainer. The subcritical extraction conditions are: extraction temperature 30°C, extraction pressure 0.4MPa, cyclic extraction for 80min, and extraction solvent flow rate of 36L / h. Crush the orange peel, pass through a 200-mesh sieve, add deionized water 7 times the weight of the orange peel, heat to 48° C. and stir for 25 minutes to obtain a mixed ...

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Abstract

The invention discloses healthcare tablets capable of increasing the bone mineral density and a preparation method and application thereof. The healthcare tablets are prepared from, by weight, 18-28 parts of folium sauropi, 3-10 parts of rhizoma valerianae jatamansi and 20-32 parts of pericarpium citri reticulatae. The preparation method comprises the steps that folium sauropi and rhizoma valerianae jatamansi are dried, smashed, mixed and delivered into an extraction kettle for subcritical extraction, and extraction liquid is prepared; pericarpium citri reticulatae is smashed and added with deionized water, and stirring under heating is performed to prepare pericarpium citri reticulatae mixed liquid; the pericarpium citri reticulatae mixed liquid and the extraction liquid are mixed and subjected to ultrasonic treatment, low-temperature decompress concentration, drying and pressing and tablet forming, and then the healthcare tablets are obtained. According to the healthcare tablets, osteoporosis and a fracture-prone symptom which are caused by bone mineral density decreasing are improved and relieved by increasing the bone mineral density under the combined action of all the raw materials; health food safety toxicology evaluation tests prove that the healthcare tablets are safe and nontoxic and can be taken for a long term; animal function tests prove that the healthcare tablets have the function of increasing the bone mineral density and are stable and controllable in quality and reasonable in dosage form.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a health care tablet for increasing bone density, a preparation method and application thereof. Background technique [0002] Osteoporosis, or osteoporosis, is a group of bone diseases caused by a variety of reasons. Bone tissue has normal calcification, and the ratio of calcium salt to matrix is ​​normal. It is a metabolic bone lesion characterized by a decrease in the amount of bone tissue per unit volume. . In most cases of osteoporosis, the loss of bone tissue is mainly due to increased bone resorption. Characterized by bone pain and susceptibility to fractures. Mainly manifested as a decrease in bone density. Modern medicine believes that the pathological mechanism of osteoporosis is mainly related to the decrease of sex hormone level, the decrease of bone mineral content, the limitation of bone mineralization deposition, and the coupling defects of bone reso...

Claims

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Application Information

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IPC IPC(8): A61K36/84A61K36/752A61K9/20A61P19/10
CPCA61K36/185A61K36/47A61K36/752A61K36/84A61K2236/37A61K2300/00
Inventor 兰志峰王玮楠
Owner SHANDONG WUZHOU DETECTION
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