Process for preparing hard hollow capsules from material having thermal gel performance

A technology of hollow capsules and manufacturing process, which is applied in the fields of capsule delivery, drug delivery, and pharmaceutical formulations. It can solve problems such as poor product quality controllability, low material utilization rate, and long disintegration time limit, and achieve the goal of eliminating mutual cross-linking reactions. risk, simplification of the production process, and the effect of shortening the drying time

Inactive Publication Date: 2016-08-10
浙江睿码科技有限公司
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  • Abstract
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  • Claims
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Problems solved by technology

[0003] The purpose of the present invention is to overcome the above-mentioned deficiencies in the prior art, adopt a kind of brand-new hollow capsule production process, aim to solve the material with thermal gel performance under the existing traditional hard hollow capsule production process, the product quality controllability is poor, Long disintegration time, slow dissolution, high energy consumption per unit product, low utilization rate of materials, etc.

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  • Process for preparing hard hollow capsules from material having thermal gel performance

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Embodiment Construction

[0022] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described in detail below through the accompanying drawings and embodiments. However, it should be understood that the specific embodiments described here are only used to explain the present invention, and are not intended to limit the scope of the present invention. Also, in the following description, descriptions of well-known structures and techniques are omitted to avoid unnecessarily obscuring the concept of the present invention.

[0023] refer to figure 1 , the embodiment of the present invention provides a kind of manufacturing technology that adopts the hard hollow capsule of material with thermogel performance, comprises the following steps:

[0024] Step 1. Preparation solution at room temperature: select materials with thermal gelation properties as raw materials for the preparation solution of hard hollow capsules. After t...

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Abstract

The invention is applicable to the technical field of production of hard hollow capsules, and discloses a process for preparing the hard hollow capsules from a material having a thermal gel performance. The process comprises the following steps: preparing a liquid at normal temperature, heating a mold body, dipping glue and forming, drying and cooling, and de-molding and brushing oil. The process for preparing the hard hollow capsules from the material having the thermal gel performance disclosed by the invention breaks through a conventional hollow capsule production process; on the basis of the principle that gel is generated by thermal gel when encountering water, exiting cold-mold hot-liquid production is replaced by cold-liquid hot-mold production, so that a preparing mode of a preparation liquid is changed, the production process is simplified, energy consumption is reduced, production cost is reduced and a material utilization rate is improved by 30-40%; and the addition of any coagulant aids is avoided, so that a risk that a mutual cross-linking reaction occurs between materials is eliminated and the safety grade of a finished product is improved. The preparation process shortens a drying time, facilitates production and management, improves a production efficiency, effectively controls the stability and the uniformity of the finished product and significantly improves the current situation that the finished product is high in weight difference.

Description

【Technical field】 [0001] The invention relates to the technical field of production of hard hollow capsules, in particular to a manufacturing process of hard hollow capsules using materials with thermogel properties. 【Background technique】 [0002] The traditional hard hollow capsule manufacturing process has been passed down for more than 100 years. The main feature of his manufacturing process is to use the principle of gelatin's own freezing force to shape. In order to ensure the stability of the molding, the ambient temperature is also required to be low. Simply put, the gelatin preparation liquid is hot, the mold is cold, and the low temperature environment is used to complete the process and meet the product requirements. Even the newly developed non-animal source hard hollow capsule manufacturing materials in recent years have not broken through this traditional model in the manufacturing process. Seaweed polysaccharide materials have properties similar to animal-de...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61J3/07
CPCA61J3/077
Inventor 诸美君徐株均孙学征
Owner 浙江睿码科技有限公司
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