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Linxia ginseng pure powder tablet and preparation method thereof

A technology of pure powder tablet and wild ginseng is applied in the field of forest ginseng pure powder tablet and its preparation, and achieves the effects of preventing the loss of effective components, having significant clinical significance and resource utilization, and low pockmark rate and splinter rate.

Active Publication Date: 2019-11-22
吉林省宣上医长白人参产业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore up to the present, also do not see the report of directly preparing tablet with Linxia mountain ginseng pure powder

Method used

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  • Linxia ginseng pure powder tablet and preparation method thereof
  • Linxia ginseng pure powder tablet and preparation method thereof
  • Linxia ginseng pure powder tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0036] Example 1, direct tableting process:

[0037] 1. Raw materials: ginseng powder under the forest, average particle size D 90 It is 15 μm; the water content is 4.5wt%.

[0038] 2. The pre-compression pressure of the tablet press is 1.2kN, and the main pressure is 45kN.

[0039] 3. When feeding the powder into the tablet press, a round bar type pulsator feeder is used to increase the fluidity of the powder.

[0040] Under the above-mentioned process conditions, the micro-powder of mountain ginseng under the forest is directly compressed into tablets, the tablet specification is 0.35g / tablet, 100 tablets.

example 2 2

[0041] Example two, secondary tabletting process:

[0042] 1. Raw materials: ginseng powder under the forest, average particle size D 90 It is 15 μm; the water content is 4.5wt%.

[0043] 2. The pre-compression pressure of the first tablet compression is 17kN, and the main pressure is 20kN; the pre-compression pressure of the second tablet compression is 17kN, and the main pressure is 20kN.

[0044] 3. When feeding the powder into the tablet press, a round bar type pulsator feeder is used to increase the fluidity of the powder.

[0045] Under the above process conditions, the first tablet is made into a primary tablet with an average hardness of 2.57Kg (the specification of the primary tablet is about 0.35g / tablet), and then crushed into a powder that can pass through a 100-mesh sieve, and then compressed into tablets using the above process conditions , tablet specification 0.35g / piece, 100 pieces.

example 3

[0046] Example three, dry granulation and tabletting process:

[0047] 1. Raw materials: ginseng powder under the forest, average particle size D 90 It is 15 μm; the water content is 4.5wt%.

[0048] 2. When the tablet press presses large flakes or plate-shaped embryos, the pre-compression pressure is 17kN, and the main pressure is 20kN; when crushed, the pre-compression pressure is 17kN, and the main pressure is 20kN.

[0049] 3. When feeding the powder into the tablet press, a round bar type pulsator feeder is used to increase the fluidity of the powder.

[0050] Under the above-mentioned process conditions, first compress the ginseng micro-powder under the forest into large flakes or plate-shaped embryos, then pulverize, granulate until it can pass through a 50-mesh sieve, and then press the above-mentioned process conditions into tablets again, the tablet specification is 0.35g / tablets, 100 tablets. (Large flaky embryos can be pressed into ginseng micropowder with a di...

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Abstract

The invention discloses a pure under-forest ginseng powder tablet and a preparation method thereof. The pure under-forest ginseng powder tablet consists of under-forest ginseng micro-powder. The preparation method comprises the following steps: removing surface earth, performing drying and slicing, continuing drying until the water content is 3 to 5 percent, performing crushing to obtain coarse powder, performing crushing to obtain under-forest ginseng micro-powder with particle sizes of less than or equal to 75 [mu]m, and performing tabletting. The pure under-forest ginseng powder tablet is pressed without any accessories, is high in dissolution rate and short in dissolution time, and active pharmaceutical ingredients can reach a blood drug concentration capable of treating diseases within the shortest time. The pure powder tablet obtained by the method is attractive in appearance and low in surface pitting rate and breaking rate, and the hardness and disintegration degree of the tablet meet tablet quality requirements.

Description

technical field [0001] The invention relates to the technical field of medicine and health care products, in particular to Linxia mountain ginseng pure powder tablet and a preparation method thereof. Background technique [0002] Ginseng is the dry root and rhizome of Panax ginseng C.A.Meyer. According to the different growth methods of ginseng, it can be divided into wild ginseng, forest ginseng, and garden ginseng. Due to the wide demand in the market and the endangerment of wild ginseng, currently forest ginseng and garden ginseng are the main sources of ginseng medicinal materials on the market. Under-forest ginseng is artificially sown the seeds of wild ginseng in the virgin forest, without any artificial interference, and allowed to grow naturally for 15-20 years. It is excavated and made into goods. The longer the growth period of under-forest ginseng, the higher the nutritional value and can Comparable to wild ginseng. The growth conditions of ginseng under the fo...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/258
CPCA61K9/20A61K36/258A61K2236/13A61K2236/15A61K2236/17
Inventor 李桂生解飞霞潘丽丽初红梅修丽杰
Owner 吉林省宣上医长白人参产业有限公司