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Application of fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid. and extract thereof in preparation of liver protecting medicine and healthcare food

A technology of health food and esse fruit, which is applied in the field of use of esse fruit and its extracts in the preparation of liver-protecting medicines or health foods, can solve the problems that esse fruit is rarely studied in modern times, and achieve prevention and treatment Clear effect, good hepatoprotective effect

Active Publication Date: 2016-08-24
SICHUAN ZHIJIACHENG BIO TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The source of Erseguo is the dried mature fruit of the same plant mentioned above. It has a long history of eating in Tibetan areas, but there are few modern studies on Erseguo

Method used

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  • Application of fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid. and extract thereof in preparation of liver protecting medicine and healthcare food
  • Application of fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid. and extract thereof in preparation of liver protecting medicine and healthcare food
  • Application of fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid. and extract thereof in preparation of liver protecting medicine and healthcare food

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0021] Experimental Example 1 Protective Effect and Mechanism of Tibetan Medicine "Eseguo" on Acute Alcoholic Liver Injury in Mice

[0022] 1 Materials and instruments

[0023] 1.1 Experimental animals SPF grade male Kunming mice, weighing 18-22g, were provided by Chengdu Dashuo Experimental Animal Co., Ltd., animal quality certificate number: SCXK (Chuan) 2013-24.

[0024] 1.2 Drugs and Reagents Ruhuo is provided by Xueyu Russia Co., Ltd., Luhuo County, Sichuan Province. It was identified as Malus toringoides (Rehd.) Hughes, a plant of the genus Malus in the family Rosaceae, by Professor Li Min of Chengdu University of Traditional Chinese Medicine. and the dried mature fruit of Malus transitoria (Batal.) Schneid.; bifendate dripping pills are products of Zhejiang Wanbang Pharmaceutical Co., Ltd., batch number: A02140302; alanine aminotransferase (ALT) test box, door The aspartate aminotransferase (AST) test kit, triglyceride (TG) kit, and low-density lipoprotein (LDL-C) kit ...

experiment example 2

[0057] Experimental Example 2 Study on the protective effect of "Russeguo" on HL7702 cell injury induced by CCl4

[0058] In this part, by observing the effect of russa fruit on the injury of human normal liver HL7702 cells induced by CCl4 in vitro, and using bifendate as a positive control, it is planned to measure the contents of ALT, AST, and LDH in the culture supernatant of HL7702 cells cultured in vitro. The level and the level of MDA, SOD, GSH in the cells were observed to observe the effect of the drug on the HL7702 cells induced by CCl4. And to further understand the protective effect of Eseguo on different liver injuries, and at the same time explore the mechanism of its hepatoprotective effect.

[0059] 1 Experimental materials

[0060] 1.1 Test materials

[0061] The experimental materials were provided by Luhuo Xueyu Russiase Co., Ltd., Sichuan Province, and were identified as Malustoringoides (Rehd.) Hughes., Malustoringoides (Rehd.) Hughes. and Malustransitori...

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Abstract

The invention discloses application of fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid. and an extract thereof in preparation of liver protecting medicine and healthcare food. The invention further provides a novel extract of the fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid.. The fruits of Malus toringoides( Rehd .)Hughes. and Malus transitoria( Batal .)Schneid. and the extract thereof are used for protecting liver and have the clear and controllable treatment effect, and a new choice is provided for clinic.

Description

technical field [0001] The present invention relates to the application of russa fruit and its extract in the preparation of liver-protecting medicine or health food. It belongs to the field of medicine. Background technique [0002] "Russian leaf" (Tibetan) is a traditional medicinal material used by the Tibetans in Ganzi Tibetan Autonomous Prefecture. It is derived from Malus toringoides (Rehd.) Hughes. and Malus tiansitoria (Batal.) Schneid. Dried leaves are usually referred to as "Russe", and a large number of existing researches are also on the cultivation of Russian leaves. [0003] The source of Erseguo is the dried mature fruit of the same plant mentioned above, which has a long history of eating in Tibetan areas, but there are few modern studies on Erseguo. Contents of the invention [0004] The technical scheme of the present invention is to provide a new application of the russian fruit or its extract. [0005] The invention provides the use of russa fruit an...

Claims

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Application Information

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IPC IPC(8): A61K36/73A61P1/16A23L33/105
CPCA61K36/73A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/53
Inventor 李敏周海玉曾俊
Owner SICHUAN ZHIJIACHENG BIO TECH CO LTD
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