64results about How to "Has hepatoprotective effect" patented technology

The invention relates to the field of health-caring foods and particularly relates to cordyceps sinensis liquor, a preparation and an application thereof. A preparation method of the cordyceps sinensis liquor includes following steps: cultivating sporocarps of cordyceps sinensis in a container through a solid fermentation method and then filling basic liquor into the container with storage. The cordyceps sinensis liquor is prepared through a novel technology, in which activated components in a culture medium and cultivated products are completely retained, instead of a conventional technology in which the clear cordyceps sinensis liquor is prepared with the cordyceps sinensis as a raw material and through a series of complex technologies including filtration, distillation and blending and the like. The cordyceps sinensis liquor is good in appearance, is mellow and delicious, maintains the main activated components, is beneficial to human health and is excellent in market prospect.

The invention discloses a method for producing giant salamander polypeptide powder liver protection capsules. The method comprises the following steps of: performing low-temperature drying, grinding, fat removal, controllable composite enzyme digestion, centrifugation, filtration, two-time membrane filtration, vacuum concentration, freeze drying and crushing on fresh giant salamander meat to obtain giant salamander polypeptide powder; encapsulating the giant salamander polypeptide powder, and packaging to obtain a finished product.

The invention relates to a method for extracting triterpenoids in dracocephalum moldavica. The extract of total triterpenes in dracocephalum moldavica is immediately obtained through concentration, hot water washing, alkali dissolving, acid precipitation, decolorization and purification by adsorption column chromatography of extracting solution of ethanol in dracocephalum moldavica. The content of total triterpenes in dracocephalum moldavica extract is not lower than 50% and the total content of oleanolic acid and ursolic acid is not lower than 80% of the content of total triterpenes. The extract of total triterpenes in dracocephalum moldavica has the effect of protecting livers and can be used for preparing drugs for liver diseases.

The invention discloses gardenia polysaccharide and an extraction method thereof. The gardenia polysaccharide is prepared from the following raw materials (by mass): 41 to 56 percent of total sugar, 34 to 45 percent of uronic acid and 7 to 10 percent of protein. The preparation method of the gardenia polysaccharide comprises the following steps: crushing a gardenia medicinal material, degreasing,adding water, extracting, precipitating with ethanol, repeatedly freeze-thawing to remove protein, dialyzing, and freeze-drying. The gardenia polysaccharide prepared by the method can improve cholestatic liver injury induced by alpha-naphthalene isothiocyanate (ANIT) and 3, 5-diethoxycarbonyl-1, 4-dihydro-2, 4, 6-trimethylpyridine (DDC), and reduce fibrosis induced by carbon tetrachloride (CCL4).And the liver protection effect of the gardenia polysaccharide is not reported in literatures, which indicates that the gardenia polysaccharide has obvious application prospects in the preparation ofliver protection drugs, especially in the preparation of anti-cholestatic liver injury and anti-hepatic fibrosis drugs.

The invention relates to the field of chemical fiber materials and discloses a preparation method for euphausiid protein regenerated cellulose fibers. The preparation method comprises the following steps: preparing a mucilage glue solution for later use; preparing a pre-cross-linked euphausiid protein solution: sequentially adding a sodium hydroxide solution, euphausiid protein and lignin sulfamic acid; agitating at 50-70 DEG C for 4-6 hours; cooling to 35-45 DEG C, keeping the heat and filtering to obtain a filtering solution, namely the euphausiid protein solution; adding a cross-linking agent into the euphausiid protein solution and keeping the heat at 35-45 DEG C to react for 0.4-0.6 hour to prepare the pre-cross-linked euphausiid protein solution; and mixing the mucilage glue solution, the pre-cross-linked euphausiid protein solution and the cross-linking agent and spinning. The fibers prepared by the preparation method have good strength; the strength of the fibers is enhanced; meanwhile, the hand feeling and the luster of the fibers are improved and the fibers can be used as raw materials of a textile industry.

The invention discloses a production method and a donkey-hide gelatin of a Chinese herbal donkey-hide gelatin material, which belong to the deep development of rare herbal donkey-hide gelatins, the technology for replacing materials of the rare herbal donkey-hide gelatins and relevant products of the rare herbal donkey-hide gelatins in the sustainable utilization field of Chinese herbal resources. According to the method, any one or multiple or all of litsea cubeba oil, lucid ganoderma, mushroom, hericium erinaceus, trametes robiniophila Murr, poria cocos, polyporus umbellatus, rainbow conk, marasmius androsaceus, armillaria mellea, false armillaria mellea, cordyceps sinensis, cordyceps militaris, tremella fuciformis, flammulina velutipes, edible fungus, grifola frondosa, gloeostereum incarnatum, schizophyllum commune, fomitopsis pinicola, cordyceps cephalosporium, paecilomyces hepialid, cordyceps gunnii penicillium, litsea cubeba, bamboo fungus, phellinus igniarius and edible fungus are added into water for peel soaking, peel removing, peel cutting, peel washing, complete peel removing and gelatin juice extraction during the production process of the Chinese herbal gelatin. The method has the most obvious characteristic that the problems that the donkey-hide gelatin material is deficient, the putrefactive odor is dispersive by the donkey-hide gelatin material during the production of the donkey-hide gelatin and the finished donkey-hide gelatin product is poor in taste are solved.

The invention provides a penthorum chinense pursh extract. The HPLC finger-print is characterized by comprising four characteristic peaks, wherein the retention time of the first peak is 10.4+ / -0.25 min, and the peak area of the first peak is 1682000+ / -8000; the retention time of the second peak is 12.5+ / -0.25 min, and the peak area of the second peak is 36750+ / -700; the retention time of the third peak is 13.0+ / -0.25 min, and the peak area of the third peak is 2461000+ / -3000; the retention time of the fourth peak is 14.9+ / -0.25 min, and the peak area of the fourth peak is 1831000+ / -5000. The treatment effect of the penthorum chinense pursh extract is excellent in treating hepatic ischemia reperfusion liver injuries and chemical liver injuries and has broad clinical application prospects.

The invention provides an application of pinocembrin dihydrogen chalcone-7-O-[3'-O-galloyl-4',6'-hexahydroxydiphenodicarboxy]-beta-D-glucoside in preparation of a liver protection medicine. The penthorum chinense pursh macrocyclic polyphenol monomer namely pinocembrin dihydrogen chalcone-7-O-[3'-O-galloyl-4',6'-hexahydroxydiphenodicarboxy]-beta-D-glucoside has a liver protection effect, can be used for preventing and treating liver injuries, and has a definite curative effect on hepatic ischemia-reperfusion injuries and chronic liver injuries, and the effect is superior to that of positive medicine namely Gansu Granules, so that the penthorum chinense pursh macrocyclic polyphenol monomer can be used for replacing the Gansu Granules and has a good clinical application prospect.

The invention relates to donkey-hide gelatin, a preparation method and associated equipment, which belong to the deep development of rare herbal donkey-hide gelatins, the technology for replacing materials of the rare herbal donkey-hide gelatins and relevant products of the rare herbal donkey-hide gelatins in the sustainable utilization field of Chinese herbal resources. According to the method, any one or multiple or all of litsea cubeba oil, lucid ganoderma, mushroom, hericium erinaceus, trametes robiniophila Murr, poria cocos, polyporus umbellatus, rainbow conk, marasmius androsaceus, armillaria mellea, false armillaria mellea, cordyceps sinensis, cordyceps militaris, tremella fuciformis, flammulina velutipes, edible fungus, grifola frondosa, gloeostereum incarnatum, schizophyllum commune, fomitopsis pinicola, cordyceps cephalosporium, paecilomyces hepialid, cordyceps gunnii penicillium, litsea cubeba, bamboo fungus, phellinus igniarius and edible fungus are added into water for peel soaking, peel removing, peel cutting, peel washing, complete peel removing and gelatin juice extraction during the production process of the Chinese herbal gelatin. The method has the most obvious characteristic that the problems that the donkey-hide gelatin material is deficient, the putrefactive odor is dispersive by the donkey-hide gelatin material during the production of the donkey-hide gelatin and the finished donkey-hide gelatin product is poor in taste are solved.

The invention provides a coumarin from Cichorium plants used for preparing drug with liver-protecting effect, and an extraction and purification method of the coumarin from Cichorium plants. The coumarin from Cichorium plants is characterized in that determined by an ultraviolet spectrophotometric method at wavelength of 350 nm with esculetin (6,7-dihydroxycoumarin) as reference substance, the coumarin has purity up to 90%. The method takes Cichorium glafulosum boiss. et Huet or Cichorium intybus L. as materials; combines ethanol extraction technology, macroporous adsorption resin enrichment technology, vacuum evaporation technology, ultrasonic extraction technology, preparative high performance liquid chromatographic (HPLC) purification technology and vacuum lyophilizing technology, to obtain the coumarin with high purity, safety, effectiveness, controllable quality and liver-protecting effect. The coumarin can be used for preparing liver-protecting drug or health food.

An anoectochilus formosanus beverage is disclosed. The beverage comprises, by mass, 0.8-1.2 per mill of anoectochilus formosanus, 0.8-1.2% of Chinese wolfberry, 4-5 per mill of liquorice, 4-5% of white granulated sugar, 1 per mill of potassium sorbate and 1 per mill of hydroxymethyl cellulose, with the balance being water. The beverage can meet the requirement that the acceptable daily intake of the anoectochilus formosanus is 15 g or below in Fujian Chinese Herbal Standard. The beverage has a hypoglycemic function, a lipid-reducing function, an antitumor function and a liver-protecting function, has effects of the liquorice, namely effects of tonifying the spleen, tonifying qi, clearing heat and toxins and expelling phlegm to arrest cough, and has effects of the Chinese wolfberry, namely effects of clearing heat, relieving cough, and improving eyesight.

The invention discloses an active site of oldenlandia diffusa as well as a preparation method and application thereof, belonging to the technical field of traditional Chinese medicines. The active site is prepared by the following steps of: getting the oldenlandia diffusa, adding 95% alcohol 15-20 times the amount of the oldenlandia diffusa, refluxing and extracting, filtering, combining extracting liquor, reducing pressure to recycle a solvent to obtain extract; dissolving the extract by hot water, filtering, carrying out macroporous resin column chromatography, eluting by alcohol liquor, collecting eluant, reducing pressure to recycle the solvent to obtain eluate; dissolving the eluate by water, filtering, carrying out polyamide column chromatography, eluting by water, collecting water eluant, reducing pressure and concentrating, and drying to obtain the active site. The method adopted in the invention is simple and suitable for industrial production; adopted separating materials are cheap and can be recycled, so that cost is lowered; finally, the obtained active site has less impurities, high purity and more obvious pesticide effect.

The invention relates to the technical field of purification of triterpenoids, medicine and health foods and particularly relates to a method for extracting and purifying triterpenoids from apple pomace and application of the triterpenoids. The method comprises the following steps of mixing dried 100-120-mesh apple pomace serving as a raw material and 95% ethanol solution at a ratio of the material to liquid being 1:18, carrying out ultrasonic extraction and drying filtrate to obtain an apple pomace triterpenoid extract; mixing the extract and petroleum ether according to a ratio of the material to liquid being (1:30)-(1:40), repeatedly washing with ultrasonic waves for 4-6 times at 40-60 DEG C and 40-60 minutes each time and drying filter residue to obtain an apple pomace triterpenoid crude extract; and finally adsorbing and eluting triterpenoids in apple pomace by macroporous resin to obtain an eluent, concentrating and drying the eluent to obtain an apple pomace triterpenoid purified product. The invention further discloses main active ingredients (ursolic acid and oleanolic acid) in the apple pomace triterpenoid crude extract and the purified product and two extracts have the characteristic of scavenging free radical and antioxidant capacity and have significant improving and protecting effect on acute liver injury.

The invention relates to the technical field of traditional Chinese medicinal material extraction technologies and medicines, in particular to a preparation method of high-activity oldenlandia diffusatotal flavonoid, namely the oldenlandia diffusa total flavonoid is extracted by directly adopting a small amount of cellulase. Compared with other extraction methods, the method disclosed by the invention is simple to operate, low in energy consumption and higher in feasibility, and the extracted total flavonoids (higher content of isoflavone components) are higher in biological activity; the method for preparing the oldenlandia diffusa total flavonoid can be used for obtaining three components which are not extracted by other extraction methods, namely dihydrokaempferol, apigenin and chrysin; six components, namely naringin, vitexin, isovitexin, genistein, luteolin and 7-O-glucoside luteolin, of which the contents are remarkably increased (up-regulated by two times or more) are obtained;the nine compounds have various biological activities such as inflammation resistance, oxidation resistance, tumor resistance, liver protection and the like; and the high-activity oldenlandia diffusatotal flavonoid extract prepared by the invention can be used for preventing and treating liver peroxidation injury and can play a role in assisting in reducing blood fat.

The invention relates to a medicinal composition for treating fatty liver comprising giant knotweed, curcuma, silymarin, silymarin and common evening primrose oil and a method for preparing same. The medicinal composition is prepared into tablet, soft capsule, capsule, drop pill and granule. It has protection function on acute liver injury and can prevent and treat fatty liver, lower blood fat, relieve blood stasis and resist overoxidation injury.

The invention belongs to the field of medicines, and relates to a pharmaceutical composition for liver injury protection and application thereof, and the pharmaceutical composition for liver injury protection is prepared from the following raw material medicines: American ginseng, hairyvein agrimony, angelica sinensis, paris polyphylla, adenophora tetraphylla and platycodon grandiflorum. The invention provides a pharmaceutical composition for liver injury protection and application thereof, wherein the pharmaceutical composition has good liver cell proliferation promoting activity, liver cell oxidative injury relieving activity and liver fibrosis resisting activity.

The invention discloses a bone-invigorating pill and a preparation method thereof. The bone-invigorating pill comprises pilose antler, herba taxilli, ginseng, white peony root, poria cocos, achyranthes root, ligusticum wallichii, Chinese angelica, prepared rehmannia root, dragon's blood, scorpion, lumbricus, cassia bark, kadsura pepper stem, caulis sinomenii, herba siegesbeckiae, pawpaw, safflower, frankincense, myrrh, radix angelicae pubescentis, licorice root, centipede, bark of ash and herba asari. The preparation method mainly comprises crushing, pelleting by a pelleting machine, drying and packaging. The bone-invigorating pill has treatment effects of tonifying liver and kidney, strengthening tendons and bones, promoting blood circulation to remove meridian obstruction, and expelling wind and removing cold, and has good clinical effects on liver and kidney deficiency-cold and anemofrigid-damp arthralgia-caused arthralgia spasm pain, femoral head necrosis and sciatica.

The invention discloses nutritive and convenient food chestnut soup and a processing method thereof. The soup is made from, by weight, 28-32% of chestnuts, 18-22% of oat, 18-22% of corn, 18-22% of cornstarch and 4-6% of green beans or small red beans. The processing method includes the following steps of cleaning and puffing all the raw materials, smashing puffed raw materials into 100 mesh to be premixed, mixing the premixed powder with, by mass, 15% of cornstarch, 20-30% of water and 5% of white sugar or 10% of barley malt syrup to be heated, scattering in the premixed powder, and putting the mixture in a mold to be cooled to obtain the chestnut soup finished product. The convenient leisure food is nutritive, delicious and convenient to eat. Two nutritional components supplement and complement each other and are beneficial to human health.

The invention relates to tea and a preparation method of the tea, and in particular relates to pseudo-ginseng health-preserving tea and a preparation method of the pseudo-ginseng health-preserving tea. The pseudo-ginseng health-preserving tea is prepared from the following raw materials in parts by weight: 3-5 parts of pseudo-ginseng, 3-5 parts of bark of eucommia, 20-30 parts of common selfheal fruit-spike, 10-20 parts of tall gastrodia tuber, 10-15 parts of glossy ganoderma and 40-50 parts of cyperus rotunus. The preparation method comprises the following steps: completely cleaning the fresh raw materials, preparing into particles, baking or drying in the sun, and then compounding according to the weight parts. The pseudo-ginseng health-preserving tea disclosed by the invention has the effects of dissipating blood stasis and stopping bleeding, dispersing swelling and settling pain, clearing away the liver fire, removing stasis and dispersing swelling, clearing heat and removing toxicity, expelling phlegm and arresting cough, treating acute infectious icteric hepatitis and bacterial dysentery, and the like.

The invention discloses a use of a perila seed extract with functions of protecting liver and lowering transaminase, relating to a use of the perila seed extract. The invention provides use of the perila seed extract with the functions of protecting liver and lowering transaminase. The method comprises the following steps of: crushing perila seeds, extracting and degreasing the perila seeds in a Soxhelt type, extracting the perial seeds by water and precipitating the perila seeds by alcohol, centrifuging, water bathing and evaporating water, freezing and drying the perila seeds to obtain the perila seed extract. A pharmacodynamics experiment on the perila seed extract shows that the perila seed extract has strong functions of protecting liver and lowering transaminase. Therefore, the perila seed extract disclosed by the invention is applied to the field of liver protection and prevention and treatment of liver diseases.

The invention provides a Chinese gentian health-care tea and a preparation method thereof. The Chinese gentian health-care tea is prepared from the following raw materials in percentage by weight: 1 to 70 percent of Chinese gentian leaf, and 30 to 99 percent of tea leaf, and the total weight percentage of the Chinese gentian leaves and the tea leaves is 100 percent. The Chinese gentian health-care tea is prepared by a certain method. The prepared Chinese gentian health-care tea can be safely applied and is non-toxic, and has the effect of protecting liver; and Chinese gentian health-care tea drinks with different flavors and tastes and in different forms can be prepared, so that different people can selectively drink according to the requirements. The invention also provides new application for the Chinese gentian leaves, so that comprehensive utilization of the Chinese gentian leaf resources is facilitated, and the social and economic benefits are increased.

The invention discloses a nanosliver haemorrhoids antibacterial agent and a preparation method thereof. The nanosliver haemorrhoids antibacterial agent comprises the following raw material medicines in parts by weight: 70-90 parts of a nanosilver colloid solution, 4-6 parts of a witch hazel extract, 1-3 parts of paeoniflorin, 2-4 parts of aucubin, 4-6 parts of matrine and 4-6 parts of a wild carrot seed extract. The nanosilver colloid solution is good in antibacterial effect, good in permeability, capable of promoting wound healing, free of drug resistance and capable of effectively preventinglong treatment caused by repeated occurrence because of drug resistance; the paeoniflorin is capable of relieving pain, calming mind, preventing inflammation and preventing ulcer; the aucubin has anti-inflammation activity; the matrine has the effects of preventing bacteria, eliminating inflammation and preventing viruses; the witch hazel extract has special treatment effects on fungal infectionand wound healing; the wild carrot seed extract is capable of intensifying erythrocyte, and thus skin can be compact and elastic, and wound scaring can be promoted; with the combination of the raw material medicines for external use, the nanosliver haemorrhoids antibacterial agent has effects of pain relieving, inflammation elimination, bacterium prevention and killing and wound healing promotionand has a very good treatment effect on haemorrhoids.

The invention relates to a pharmaceutical composition for treating fatty liver and a preparation method thereof. The active ingredients contained in the traditional Chinese medicine composition are made from Polygonum cuspidatum, turmeric, silymarin and evening primrose oil. The pharmaceutical compositions of the present invention are tablets, soft capsules, capsules, dropping pills and granules. The traditional Chinese medicine composition of the invention has protective effect on acute liver injury, prevention and treatment effect on fatty liver, strong anti-peroxidative damage ability, blood lipid-lowering effect and blood rheology improvement effect on blood stasis syndrome, and can be used for treatment fatty liver.

The invention belongs to the field of traditional Chinese medicines, and specifically relates to a traditional Chinese medicine composition containing finger citron. The composition includes, in partsby weight, 3-5 parts of finger citron, 3-5 parts of glossy privet fruits, 1-3 parts of Japanese thistle herbs, 0.5-1.5 parts of Pu'er tea, 0.5-1.5 parts of chitosan, 2-4 parts of common yam rhizome and 2-4 parts of oriental waterplantain rhizome. The composition has effects of losing weight, reducing lipid and improving insulin resistance, is safe, reliable and good in stability, can be taken fora long time and has protection effects on livers.

The invention discloses a traditional Chinese medicine composition for treating hepatitis and liver cancer, comprising the following raw material medicines according to parts by weight: 1 to 120 parts of rhein or rhubarb class substances capable of being metabolized into the rhein in vivo, 1 to 50 parts of quercetin or quercetinic acid glucoside class substances capable of metabolized into the quercetinic acid in vivo and 3 to 60 parts of vinegar radix bupleuri, wherein the rhein is a market-sold product artificially synthesized or naturally extracted, and the purity is more than or equal to 80%. The composition can be prepared into various traditional Chinese medicine preparation medicines which can suppress the multiplication of liver cancer cells and promote the death of the liver cancer cells; an animal experiment validates that compared with the original anticancer medicine, the medicine can greatly enhance the concentration of the medicine in the liver and prolong the detention time of the medicine.

The invention provides liver-protecting substitutional tea. The liver-protecting substitutional tea is prepared from the following raw materials in parts by weight: 20 to 30 parts of flos chrysanthemi, 15 to 25 parts of leaves of broadleaf holly, 10 to 18 parts of herba taraxaci, 10 to 25 parts of rhizoma polygonati, 8 to 12 parts of semen cassiae, 8 to 12 parts of radix puerariae and 4 to 10 parts of poria cocos, and a corresponding preparation method is adopted; the liver-protecting substitutional tea disclosed by the invention has a liver protection effect.

The invention discloses a new saponin compound with the hepatoprotective effect. The new triterpenoid saponin compound is obtained and separated from licorice root through spectrum and mass spectrometric data analysis after systematic study on chemical components of liquorice. Pharmacological experimental study shows that by utilizing the saponin compound, serum ALT, AST activity and liver tissue MDA content of CCl4 induced hepatic injury model mouse, ethyl alcohol induced hepatic injury model mouse and D-galactosamine induced hepatic injury model mouse can be obviously reduced, SOD activity of liver can be strengthened, and the saponin compound has obvious protective effect on liver injury. Toxicity experimental study shows that the new saponin compound with the hepatoprotective effect does not have significant toxicity and can be developed to a new medicine or health care product with the hepatoprotective effect.

The invention discloses a traditional Chinese medicine liver protection composition, a traditional Chinese medicine liver protection preparation and a traditional Chinese medicine liver protection tea, wherein the traditional Chinese medicine liver protection composition is prepared from the following raw materials in parts by weight: 10-20 parts of schisandra, 10-20 parts of wolfberry, three parts by weight Seven 8-15 parts, Salvia 8-15 parts, Astragalus 8-15 parts, Red dates 5-10 parts, Licorice 5-10 parts. The invention provides a traditional Chinese medicine liver protection composition, a traditional Chinese medicine liver protection preparation and a traditional Chinese medicine liver protection tea prepared by using common traditional Chinese medicines, wherein the wolfberry fruit and red date are both medicinal and edible medicinal materials; They are all raw materials that can be used in health food, and they all have hepatoprotective effects. The traditional Chinese medicine liver protection composition, the traditional Chinese medicine liver protection preparation and the traditional Chinese medicine liver protection tea can effectively improve liver function, are mild in nature, have no side effects, and can be taken for a long time.

The invention relates to the technical field of health-care products and discloses beautifying and dredging cream. The beautifying and dredging cream is prepared from the following raw materials in parts by weight: 3 to 7 parts of rhizoma zingiberis recens, 15 to 25 parts of fructus jujubae, 20 to 40 parts of mulberries, 15 to 25 parts of uncooked pears, 4 to 8 parts of pericarpium citri reticulatae, 20 to 40 parts of black sesame and 15 to 25 parts of honey. According to the beautifying and dredging cream and the preparation method thereof, the mulberry and the black sesame are arranged; themulberry has sweetness, coolness and sour, attribute to liver and kidney channels and the efficiency of replenishing blood, nourishing Yin, engendering liquid and allaying thirst, and can be used fortreating constipation, parched mouth and scorched toque, and the like caused by insufficiency of liquid and blood, as well as blackening hairs and improving eyesight, beautifying skin and resisting aging; the black sesame is sweet and natural, is attributive to liver, kidney and large intestine meridian, has the efficacy of nourishing liver and kidney, boosting essence blood and moistening dry intestine, and can be used for preventing and curing constipation due to intestinal dryness; moreover, the black sesame also can be used for preventing and treating symptoms such as dizziness and premature graying of hair; the uncooked pear has the effects of clearing heat and promoting fluid, moistening dryness and resolving phlegm, moistening lung and promoting the secretion of saliva or body fluidand assisting intestines in smoothly relaxing the bowels, and can be used for lubricating the intestine so as to discharge toxic substances out of a body.