Veterinary-use soluble powder and preparation method and application method thereof

A technology of soluble powder and co-solvent, which is applied in the direction of non-active ingredient medical preparations, medical preparations containing active ingredients, powder delivery, etc. It can solve the problems of poor antibacterial efficacy and achieve cost saving, convenient operation, and guaranteed dissolution sexual effect

Inactive Publication Date: 2016-10-12
合肥中龙神力动物药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] In order to solve the problems existing in the prior art, the present invention provides a soluble powder for veterinary use, which solves the problem of poor antibacterial efficacy when administered in drinking water

Method used

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  • Veterinary-use soluble powder and preparation method and application method thereof
  • Veterinary-use soluble powder and preparation method and application method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Neomycin sulfate 3.25kg

[0028] Purple potato starch 80kg

[0029] Anhydrous glucose added to 100kg

[0030] Preparation method: superfinely pulverize neomycin sulfate, pass it through No. 9 sieve (according to Pharmacopoeia, the inner diameter (average value) of No. 9 sieve hole is: 75±4.1um), and become a very fine powder. Dry treatment of neomycin sulfate, anhydrous glucose and purple potato starch; weigh the treated neomycin sulfate, anhydrous glucose and purple potato starch according to the prescription, and fully mix them according to the method of equal increment; Soluble powder was obtained.

Embodiment 2

[0032] Neomycin Sulfate 6.5kg

[0033] Purple potato starch 50kg

[0034] Sucrose up to 100kg

[0035] Preparation method: superfinely pulverize neomycin sulfate, pass it through a No. 9 sieve to become a very fine powder, dry the treated neomycin sulfate, sucrose and purple potato starch; weigh the treated sulfuric acid according to the prescription Neomycin, sucrose and purple sweet potato starch are fully mixed and evenly distributed according to the method of equal increase;

Embodiment 3

[0037] Neomycin sulfate 32.5kg

[0038] Purple potato starch 10kg

[0039] Citric acid 0.03kg

[0040] Add lactose to 100kg

[0041] Preparation method: superfinely pulverize neomycin sulfate, pass it through a No. 9 sieve to become a very fine powder, dry the treated neomycin sulfate, lactose, citric acid and purple potato starch; weigh according to the prescription The treated neomycin sulfate, lactose, citric acid and purple potato starch are thoroughly mixed and evenly distributed according to the method of equal volume increase;

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Abstract

The invention belongs to the field of veterinary medicine and discloses veterinary-use soluble powder and preparation method and application method thereof. The veterinary-use soluble powder is prepared by using optional one of neomycin sulfate, apramycin sulfate and erythromycin thiocyanate as the active component, using filling agent and solubilizing assistant as the auxiliary materials and adding purple sweet potato starch. The preparation method includes: performing superfine crushing on the active component, and sieving with a No.9 sieve; respectively weighing the processed active component, the filling agent, the solubilizing assistant and the purple sweet potato starch according to formula weight, and evenly mixing with an equal-increasing mixing method. The application method includes: adding the soluble powder into water, and adding alkali substances into the solution if the solution is red until the solution suddenly changes from red to blue; adding alkali substances into the solution if the solution is purple until the solution is gradually changed into yellowish brown. By the veterinary-use soluble powder, the optimal effect of antibacterial drugs can be achieved, abuse of the antibacterial drugs can be avoided, and cost is saved.

Description

technical field [0001] The invention belongs to the field of veterinary medicine, and in particular relates to a veterinary soluble powder, a preparation method and a use method thereof. Background technique [0002] In recent years, animal husbandry needs to use a large number of various antibacterial drugs. Antibacterial drugs can interfere with the synthesis of the cell wall of pathogenic microorganisms, damage the cell membrane of the bacteria, and affect the protein synthesis and nucleic acid synthesis of the bacteria. Neomycin sulfate, apramycin sulfate, and erythromycin thiocyanate are commonly used veterinary antibacterial drugs. These antibacterial drugs have enhanced antibacterial effects in alkaline environments. Alkali, etc.) can enhance the antibacterial effect, when the pH value exceeds 8.4, the antibacterial effect will be weakened. [0003] Commonly used methods of administration include: mixing materials, drinking water, injection and aerosol administratio...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K31/7048A61K31/7036A61K47/36A61K47/02A61K47/12A61K47/20A61K47/32A61K47/34A61P31/04A61K31/352A61K31/718
CPCA61K9/143A61K9/145A61K9/146A61K31/352A61K31/7036A61K31/7048A61K31/718A61K2300/00
Inventor 乐其新汪洋
Owner 合肥中龙神力动物药业有限公司
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