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Medicinal composition as well as preparation method and applications thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, plant raw material, etc., can solve problems such as adverse reactions, and achieve the effects of easy portability, high safety, and convenient taking.

Active Publication Date: 2016-10-12
HUNAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mainly focuses on anticoagulation, antiplatelet therapy, and lipid-lowering therapy, but there are many adverse reactions, and some treatments need further clinical verification

Method used

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  • Medicinal composition as well as preparation method and applications thereof
  • Medicinal composition as well as preparation method and applications thereof
  • Medicinal composition as well as preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] A pharmaceutical composition prepared from the following raw materials in parts by weight: 15 parts of Agrimony, 10 parts of Salvia miltiorrhiza, 8 parts of peach kernel, 12 parts of Jiangxiang, 15 parts of Ophiopogon japonicus, 5 parts of Coptis chinensis, 10 parts of Scrophulariaceae, 10 parts of 1 part paeonol, 6 parts leech.

Embodiment 2

[0049] A pharmaceutical composition prepared from the following raw materials in parts by weight: 10 parts of Agrimony, 5 parts of Danshen, 5 parts of peach kernel, 10 parts of Jiangxiang, 10 parts of Ophiopogon japonicus, 3 parts of Coptis chinensis, 5 parts of Scrophulariaceae, 5 parts of 1 part paeonol, 3 parts leech.

Embodiment 3

[0051] A pharmaceutical composition prepared from the following raw materials in parts by weight: 20 parts of Agrimony, 15 parts of Danshen, 10 parts of peach kernel, 15 parts of Jiangxiang, 20 parts of Ophiopogon japonicus, 6 parts of Coptis chinensis, 15 parts of Scrophulariaceae, 15 parts of Danpi, 10 leeches.

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Abstract

The invention relates a medicinal composition as well as a preparation method and applications of the medicinal composition. The medicinal composition is prepared from the following medicinal materials: herba agrimoniae, radix salviae miltiorrhizae, peach kernels, lignum dalbergiae odoriferae, radix ophiopogonis, rhizoma coptidis, radix scrophulariae, cortex moutan and leeches. Herba agrimoniae and radix salviae miltiorrhizae are taken as monarch drugs, peach kernels, lignum dalbergiae odoriferae and cortex moutan are taken as ministerial drugs, radix ophiopogonis, radix scrophulariae and leeches are taken as assistant drugs, the monarch drugs, the ministerial drugs and the assistant drugs perform the corresponding roles and are also matched with each other, and thus the medicinal composition has the efficacies of clearing Ying heat and eliminating toxins, promoting blood circulation to remove meridian obstruction, and strengthening the body resistance, especially has the functions of improving the cardiac function and the myocardial pathological form, promoting the angiogenesis, inhibiting the myocardium cell apoptosis, inhibiting the inflammatory reaction, protecting the endothelial cells, and the like, and has very good curative effects in treating or preventing coronary heart disease.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition, a preparation method and an application. Background technique [0002] At present, due to changes in environmental conditions, dietary changes, and population aging, cardiovascular disease has become the leading cause of death for humans. The Global Burden of Disease study published in "The Lancet" in 2012 showed that between 1990 and 2010, 235 of the global population Among the causes of death, ischemic heart disease ranks first, and stroke ranks second. The principle of clinical treatment of coronary heart disease has always been to restore blood reperfusion as soon as possible, so that the ischemic myocardium can be supplied with oxygen again, provide nutrients necessary for metabolism and remove metabolic waste. Since the 1980s, with the development of modern medicine, cardiac reperfusion therapy such as intravenous thrombol...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P9/10A61K35/62
CPCA61K9/2068A61K35/62A61K36/48A61K36/537A61K36/71A61K36/718A61K36/73A61K36/736A61K36/808A61K36/8968A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 李鑫辉黄淼鑫杜建芳李雅婧肖青郭晨鹤
Owner HUNAN UNIV OF CHINESE MEDICINE
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