Silymarin gradient extraction method using ethyl alcohol

Abstract

The invention relates to a silymarin extraction method. The silymarin extraction method is characterized in that silymarin seeds are added into a hulling machine for hulling; silymarin hulls and ethyl alcohol are loaded into pot group type gradient extraction equipment; gradient extraction is conducted on the silymarin hulls, and a primary extracting solution of silymarin is obtained; the primary extracting solution is concentrated, and a silymarin concentrated solution is obtained; an alkaline solution is added into the concentrated solution, stirring is conducted, and standing and sedimentation are conducted; the sediments are filtered, dried, crushed and screened, and therefore silymarin is obtained. According to the silymarin extraction method, a gradient extraction mode is adopted, the extraction rate of extracting silymarin is increased, and the production energy consumption and production cost are reduced.

Description

technical field [0001] The embodiment of the present invention relates to a production method, in particular to a production method of silymarin. Background technique [0002] Silymarin is a mixture of flavonoid lignans derived from the seeds of the plant Silybum marianum in the family Asteraceae. Its main components include flavonoids such as silibinin, isosilibinin, dehydrosilibinin, silybinin and silybinin. Silymarin has the function of protecting the liver and promoting choleresis, and is mainly used for the treatment of liver diseases. Secondly, it also has obvious anti-lipid peroxidation, anti-radiation, scavenging free radicals, anti-gastric ulcer and other effects. It has good effects in reducing blood fat, preventing and treating atherosclerosis, preventing cerebral ischemia, and anti-platelet aggregation. Non-toxic, non-teratogenic and mutagenic. [0003] At present, there are two main extraction methods of silymarin, one is organic solvent extraction, and the ...

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Problems solved by technology

The problem with this method is that after the milk thistle seeds are crushed, the oil cannot be completely extracted, which will have a certain impact on the subsequent extraction purity of silymarin; another technique is to shell the milk thistle seeds first, and then use water Silymarin is extracted from silymarin shells to avoid the influence of oil in milk thistle seeds, but this method needs to be shelled separately, and the extraction process is not thorough. Milk thistle meal contains silymarin that has not been completely extracted. To obtain When the same amount of silymarin, increased extraction time cost and economic cost

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