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Automatic Protein Chip Analyzer

A protein chip and analyzer technology, applied in the field of research equipment, can solve problems such as labeling cross-contamination, tedious labor, and quantitative difficulties, and achieve the effects of improving accuracy, reducing labor, and speeding up efficiency

Active Publication Date: 2018-09-14
GUIZHOU JINJIU BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The inventor found in the research that the existing technology has complex requirements for reagents, cumbersome operation steps, and difficult quantification. The labeling is easy to cause cross-contamination, and the detection of multiple markers requires long-term tedious labor and high cost. cost, it is difficult to promote

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] see Figure 1-Figure 4 , Embodiment 1 of the present invention provides a fully automatic protein chip 102 analyzer, including a frame 400, a sample container 200, a rotating disk 700, a turning device 900, a cleaning system 1000, an observation system 300, a reaction system, and an electric control system 500 and motion system 600 .

[0042] The observation system 300 , the cleaning system 1000 , the rotating disk 700 , the turning device 900 , the reaction system, the movement system 600 and the electric control system 500 are all connected to the frame 400 .

[0043] Frame 400 comprises workbench 440, and reaction system comprises reaction platform 114, and reaction platform 114 is connected with workbench 440, and motion system 600 and reaction system are all electrically connected with electronic control system 500, and reaction system comprises reactor 100, and observation system 300 uses In order to observe the reaction of the reactor 100, the motion system 600 ...

Embodiment 2

[0061] see Figure 5-Figure 8 , Embodiment 2 of the present invention provides a reactor, including a chip holder 101, a first reaction membrane 103, a reactor body 104 and a chip 102 for detecting the reaction process.

[0062] The chip 102 is fixed on the bottom of the chip holder 101, the top wall of the first reaction film 103 contacts the bottom wall of the chip 102, the top wall of the reactor main body 104 contacts the bottom wall of the first reaction film 103, and the main body of the reactor is provided with The liquid inlet channel 110 and the liquid outlet channel 111, the liquid inlet channel 110 and the liquid outlet channel 111 run through the reactor body 104 vertically, the bottom of the liquid inlet channel 110 is used to contact the reaction liquid, and the first reaction membrane 103 is provided with a drainage The chamber 109 , the liquid inlet channel 110 and the liquid outlet channel 111 are all in communication with the drainage chamber 109 .

[0063] ...

Embodiment 3

[0080] see Figure 9 and Figure 10 , Embodiment 3 of the present invention provides a reactor, including a chip holder 101, a first reaction membrane 103, a reactor body 104, a grasping hole 107, a peristaltic pump, and a chip 102 for detecting the reaction process.

[0081] The chip 102 is fixed on the bottom of the chip holder 101 , the top wall of the first reaction film 103 is in contact with the bottom wall of the chip 102 , and the top wall of the reactor body 104 is in contact with the bottom wall of the first reaction film 103 . The main body of the reactor is provided with a liquid inlet channel 110 and a liquid outlet channel 111, and both the liquid inlet channel 110 and the liquid outlet channel 111 vertically penetrate the reactor main body 104, and the bottom of the liquid inlet channel 110 is used for contacting with the reaction liquid. The reaction membrane 103 is provided with a drainage chamber 109 , and both the liquid inlet channel 110 and the liquid out...

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Abstract

The invention provides a full-automatic protein chip analysis meter and belongs to the field of research instruments. The full-automatic protein chip analysis meter comprises a frame, a sample container, an observing system, a reaction system, an electric control system and a motion system, wherein the observing system, the reaction system, the motion system and the electric control system are all connected with the frame; the sample container is used for containing the sample; the sample is used for contacting with and reacting in the reactor; the frame comprises a workbench; the reaction system comprises a reaction platform; the reaction platform is connected with the workbench; the motion system and the reaction system are electrically connected with the electric control system; the reaction system comprises a reactor; the observing system is used for observing the reaction condition of the reactor; the motion system comprises a mechanical arm used for performing experiment; the mechanical arm is used for transferring the reactor to the reaction platform; the mechanical arm is also used for grasping once sucker and adding the sample into the reactor. The protein analysis step is automatic, the probability of cross infection in test is reduced and the experimental efficiency and accuracy are increased.

Description

technical field [0001] The invention relates to the field of research equipment, in particular to an automatic protein chip analyzer. Background technique [0002] At present, the detection technology in medical institutions mainly uses the traditional immunoassay technology of enzyme-linked immunoassay and automatic chemiluminescence immunoassay for single-index detection. ELISA technology is mainly composed of sample adding plate, egg incubator, microplate reader, plate washer, and data processing module. The basic principle of this technology is: ① Make the antigen or antibody bind to the surface of some kind of solid phase carrier, and keep its immunological activity. ②The antigen or antibody is connected with an enzyme to form an enzyme-labeled antigen or antibody, which not only retains its immune activity, but also retains the activity of the enzyme. During the determination, the test specimen (to determine the antibody or antigen in it) and the enzyme-labeled antig...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N35/00G01N35/02G01N21/75G01N21/21
CPCG01N21/211G01N21/75G01N35/00029G01N35/00584G01N35/0099G01N35/025G01N2035/00158G01N2035/0437
Inventor 韩克兵王磊周庭波张思宇郑世阳任占涛刘炜进曾世洪陈汉柒綦小三刘念王雪静张亚
Owner GUIZHOU JINJIU BIOTECH
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