Fully-automatic plasma treatment equipment and fully-automatic plasma treatment method

Abstract

The present invention discloses fully-automatic plasma treatment equipment, which comprises a pH pump for conveying a pH value adjusting liquid, an acetic acid pump for conveying acetic acid, and an ethanol pump for conveying ethanol, wherein the pH pump, the acetic acid pump and the ethanol pump are connected in parallel and then are communicated to the inlet end of a first mixer, the outlet end of the first mixer is sequentially connected to a buffer liquid trap and a buffer liquid tank in series, a feedback controller is arranged between the buffer liquid trap and the buffer liquid tank, and is respectively connected to the pH pump, the acetic acid pump and the ethanol pump in a controlled manner, the fully-automatic plasma treatment equipment further comprises a three-way valve, the first port of the three-way valve is communicated to the buffer liquid tank, the second port of the three-way valve is communicated to a plasma precipitation reaction pool, the third port of the three-way valve is communicated to a buffer liquid pump, the buffer liquid pump and a plasma pump for conveying plasma are connected into the inlet end of the second mixer in parallel, and the outlet end of the second mixer is communicated to the buffer liquid tank. According to the present invention, fully-automatic plasma treatment equipment is completely-automated, and precisely controls the conductivity, the ethanol concentration and the pH value of the buffer liquid so as to precipitate the proteins in the plasma.

Description

technical field [0001] The invention belongs to the technical field of plasma processing equipment, and in particular relates to a fully automatic plasma processing equipment and a method thereof. Background technique [0002] In the traditional plasma processing scheme, it is often necessary to use a large (10,000 liter) buffer tank, but the storage space of the large buffer tank is insufficient, and it is difficult to prepare a 10,000L batch of treatment solution in a large buffer tank, feeding, human error, mixing, etc. The variability of the treatment method has been repeatedly banned, the acidity and ionic strength are not easy to control, and the ethanol concentration, conductivity and pH fluctuations cannot be completely controlled, thereby affecting the solubility of the protein. The yield and purity are not ideal. Manual production costs are high. Reproducibility is poor. Therefore, there is an urgent need to improve the traditional plasma processing scheme so that...

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Problems solved by technology

[0002] In the traditional plasma processing scheme, it is often necessary to use a large (10,000 liter) buffer tank, but the storage space of the large buffer tank is insufficient, and it is difficult to prepare a 10,000L batch of treatment solution in a large buffer tank, feeding, human error, mixing, etc. The variability of the treatment method has been repeatedly banned, the acidity and ionic strength are not easy to control, and the ethanol concentration, conductivity and pH fluctuations cannot be completely controlled, thereby affecting the solubility of the protein. The yield and purity are not ideal. Manual production costs are high. poor reproducibility

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