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Traditional Chinese medicine composition with uric acid reducing efficacy as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition with uric acid-lowering effect and preparation thereof, can solve abnormality, diarrhea, headache, joint-related signs and symptoms, and musculoskeletal/connective tissue symptoms, see gastrointestinal reactions , rash, fever and other adverse reactions, deficiency, aplastic anemia and other problems, to achieve the effect of not easy to recur, long taking period, and easy to draw materials

Inactive Publication Date: 2017-03-15
北京万源普达医疗科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs have a good curative effect on the treatment of gout, they all show certain toxic and side effects in clinical practice. Among them, the adverse reactions of febuxostat include abnormal liver function, diarrhea, headache, joint-related signs and symptoms and muscle pain. Bone / connective tissue symptoms; allopurinol common adverse reactions such as rash, diarrhea, abdominal pain, low fever, transient transaminase elevation or neutropenia; colchicine is highly toxic, common nausea, vomiting, diarrhea, abdominal pain, gastrointestinal reactions, Hematuria, oliguria, direct inhibitory effect on bone marrow, causing agranulocytosis, aplastic anemia, etc.; benzbromarone can cause neutropenia; probenecid common gastrointestinal reactions, rash, fever and other adverse reactions, long-term The use of these drugs brings great pain to patients, threatens health and affects quality of life

Method used

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  • Traditional Chinese medicine composition with uric acid reducing efficacy as well as preparation method and application thereof
  • Traditional Chinese medicine composition with uric acid reducing efficacy as well as preparation method and application thereof
  • Traditional Chinese medicine composition with uric acid reducing efficacy as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] The preparation of embodiment 1 Chinese medicine composition

[0048] Get 350kg of Chinese herbal medicine Smilax smilax, 250kg of Rhizoma chinensis, and 650kg of flat lying chrysanthemum notoginseng, and use 50% ethanol reflux extraction that is equivalent to 5 times of raw material weight, extract altogether 2 times, each time 3 hours, combine extracts, filter, reduce Press and concentrate to obtain a liquid extract, and spray-dry to obtain a dry powder of the extract.

[0049] Another 400 kg of barley seedlings were taken, freeze-dried, pulverized by steam flow, and sterilized to obtain barley seedling dry powder.

[0050] The extract dry powder is mixed with the barley grass dry powder to obtain the traditional Chinese medicine composition.

[0051] For the preparation process of extract dry powder, see figure 1 .

Embodiment 2

[0052] The preparation of embodiment 2 Chinese medicine composition

[0053] Get 800kg of Chinese herbal medicine Smilax smilax, 600kg of Rhizoma chinensis, and 2000kg of flat lying chrysanthemum notoginseng, and reflux extraction with 50% ethanol equivalent to 5 times the weight of the raw materials, extracting 2 times, each time for 3 hours, combining the extracts, filtering, and reducing Press and concentrate to obtain a liquid extract, and spray-dry to obtain a dry powder of the extract.

[0054] Another 1500 kg of barley seedlings was taken, freeze-dried, crushed by steam flow, and sterilized to obtain barley seedling dry powder.

[0055] The extract dry powder is mixed with the barley grass dry powder to obtain the traditional Chinese medicine composition.

Embodiment 3

[0056] The preparation of embodiment 3 Chinese medicine composition

[0057] Get 1200kg of Chinese herbal medicines Smilax smilax, 800kg of Rhizoma chinensis, and 1500kg of flat lying chrysanthemum notoginseng, reflux extraction with 50% ethanol equivalent to 5 times the weight of the raw materials, extract 2 times, each time for 3 hours, combine the extracts, filter, reduce Press and concentrate to obtain a liquid extract, and spray-dry to obtain a dry powder of the extract.

[0058] Another 1000 kg of barley seedlings was taken, freeze-dried, crushed by steam flow, and sterilized to obtain barley seedling dry powder.

[0059] The extract dry powder is mixed with the barley grass dry powder to obtain the traditional Chinese medicine composition.

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Abstract

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition with uric acid reducing efficacy as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from rhizome smilacis glabrae, rhizoma corydalis, gynura procumbens and young barley grass. After rhizome smilacis glabrae, rhizoma corydalis, gynura procumbens and young barley grass are combined according to a scientific formula, the uric acid reducing efficacy of traditional Chinese medicine composition is better than that of rhizome smilacis glabrae, or gynura procumbens and young barley grass, and the traditional Chinese medicine composition can be used for treating gout. Clinical experimental results show that the total effective rate of a traditional Chinese medicine preparation reaches 98 percent.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition with the effect of lowering uric acid, a preparation method and application thereof. Background technique [0002] With the improvement of people's living standards and changes in eating habits, the incidence of hyperuricemia and gout in my country has been increasing year by year in recent years. Hyperuricemia is a disease in which blood uric acid exceeds the normal value due to purine metabolism disorder and / or uric acid excretion disorder, and it does not show any symptoms clinically. When the human body is in the condition of hyperuricemia for a long time, uric acid is precipitated in the joints, soft tissues, cartilage and kidneys in the form of sodium salt, causing human organ and tissue lesions, leading to gout, and causing serious complications, including gouty Arthritis, gouty nephropathy, gouty kidney ston...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/8998A61P19/06A23L33/105A23L33/10
CPCA61K36/90A23V2002/00A61K36/28A61K36/66A61K36/896A61K36/8998A61K2236/333A61K2236/39A61K2300/00A23V2200/30A23V2250/21
Inventor 蔡东明温晓斌
Owner 北京万源普达医疗科技有限公司
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