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Pharmaceutical composition for treating tuberculous pleuritis

A technology for tuberculous pleurisy and a composition, applied in the field of medicine, can solve the problems of good curative effect, large side effects, unsatisfactory curative effect and the like, and achieve the effects of quick effect, low recurrence rate, no toxic side effects and allergic reactions

Inactive Publication Date: 2017-05-31
HENAN SHUIJINGTOU CULTURAL MEDIA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional Chinese medicine has achieved good curative effect in the treatment of this disease, but there are still some problems: clinically, the curative effect obtained in reducing the adverse reaction of pleural effusion absorption and shortening the course of the disease is not satisfactory.
The curative effect of western medicine is good, the side effect is big

Method used

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  • Pharmaceutical composition for treating tuberculous pleuritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1 part of artemisinin, 3 parts of chlorpheniramine maleate, 15 parts of nicotinamide, and azithromycin Mycin 11 parts.

[0018] Mix and grind chlorpheniramine maleate and azithromycin, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 48 minutes to prepare mixture A. Mix nicotinamide with mixture A, stir at 60°C for 23 minutes, add artemisinin, then ultrasonicate at 43°C for 33 minutes, ultrasonic power is 800W, then stir at 55°C until dry and granulating to obtain the pharmaceutical composition.

Embodiment 2

[0020] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 3 parts of artemisinin, 7 parts of chlorpheniramine maleate, 23 parts of nicotinamide, and azithromycin Mycin 19 parts.

[0021] Mix and grind chlorpheniramine maleate and azithromycin, add 6.2 times the mass of deionized water, and stir at 66°C for 50 minutes to prepare mixture A. Mix nicotinamide with mixture A, stir at 60°C for 25 minutes, add artemisinin, then ultrasonicate at 43°C for 33 minutes, ultrasonic power is 800W, then stir at 55°C until dry and granulating to obtain the pharmaceutical composition.

Embodiment 3

[0023] In an embodiment of the present invention, a pharmaceutical composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1.5 parts of artemisinin, 4 parts of chlorpheniramine maleate, 17 parts of nicotinamide, and azithromycin Mycin 13 parts.

[0024] Mix and grind chlorpheniramine maleate and azithromycin, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 49 minutes to prepare mixture A. Mix nicotinamide with mixture A, stir at 60°C for 24 minutes, add artemisinin, then ultrasonicate at 43°C for 33 minutes, ultrasonic power is 800W, and then stir at 55°C until dry and granulating to obtain the pharmaceutical composition.

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Abstract

The invention discloses a pharmaceutical composition for treating tuberculous pleuritis. The pharmaceutical composition is prepared by the following raw materials by weight: 1-3 parts of artemisinin, 3-7 parts of chlorpheniramine maleate, 15-23 parts of nicotinamide, and 11-19 parts of azithromycin. The preparation method comprises the following steps: mixing and grinding the chlorpheniramine maleate and the azithromycin, adding deionized water, stirring for 48-50 min under 66 DEG C of the temperature, to obtain a mixture A; mixing the nicotinamide and the mixture A, stirring for 23-25 min under 60 DEG C of the temperature, adding the artemisinin, and carrying out the ultrasonic treatment for 33 min under 43 DEG C of the temperature, stirring under 55 DEG C of the temperature until the solution is dried, and pelleting to obtain the pharmaceutical composition. The pharmaceutical composition is used for treating the tuberculous pleuritis, the treatment effect is remarkable, the cure rate is high, the treatment time is short, the effective speed is quick without the toxic and side effect and anaphylactic reaction, the recurrence rate is low, the cost is cheap, and the drug dosage is less. The pharmaceutical composition is an ideal pharmaceutical.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating tuberculous pleurisy. Background technique [0002] Tuberculous pleurisy is a pleural inflammation caused by Mycobacterium tuberculosis and its autolyzed products and metabolites entering the pleural cavity of ultra-sensitive organisms. Tuberculous pleurisy is the disease caused by Mycobacterium tuberculosis first invading the body. The majority of tuberculous pleurisy in my country is caused by Mycobacterium tuberculosis. Most tuberculous pleurisy is acute. The symptoms are mainly systemic poisoning symptoms of tuberculosis and local symptoms caused by pleural effusion. The symptoms of tuberculosis poisoning are mainly manifested as fever, chills, sweating, fatigue, loss of appetite, and night sweats. Local symptoms include chest pain, dry cough, and dyspnea. Chest pain is usually located below the anterior axillary line or posteri...

Claims

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Application Information

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IPC IPC(8): A61K31/7052A61K9/16A61P31/06A61P11/00A61K31/366A61K31/4402A61K31/455
CPCA61K31/366A61K9/1605A61K31/4402A61K31/455A61K31/7052
Inventor 不公告发明人
Owner HENAN SHUIJINGTOU CULTURAL MEDIA CO LTD