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Preparation method for ultra-fine pure ginseng powder tablet

A technology of ginseng powder and pure powder tablets, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, and devices that make drugs into special physical or ingestible forms, and can solve problems such as crystal transformation and activity reduction, Improve taste, uniform color and good granulation effect

Active Publication Date: 2017-05-31
中民康达药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The pure powder buccal tablets prepared by this method are granulated by dry method, and the compression step is likely to cause crystal transformation and activity reduction, etc.

Method used

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  • Preparation method for ultra-fine pure ginseng powder tablet
  • Preparation method for ultra-fine pure ginseng powder tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] A preparation method of ginseng ultrafine powder, comprising the following steps:

[0067] Step 1: Wash ginseng, remove impurities, and vacuum freeze-dry;

[0068] Step 2: coarsely pulverizing ginseng, and further pulverizing the coarsely pulverized ginseng with a vibrating rod machine to obtain fine ginseng powder;

[0069] Among them, the process parameters of the vibrating rod machine are: the speed of the rod machine is 900r / min, and the diameter of the white steel rod is 30mm;

[0070] Step 3: preheating the ginseng fine powder to 42°C, and at the same time, controlling the humidity of the ginseng fine powder to be 30%;

[0071] Step 4: Add the ginseng fine powder obtained in step 3 into the boiling granulator, and control the temperature of the boiling granulator to be 62°C;

[0072] Step 5: Add purified water to the ginseng fine powder through a peristaltic pump for granulation, control the wind speed of the boiling machine, so that the ginseng powder and purif...

Embodiment 2

[0075] A preparation method of ginseng ultrafine powder, comprising the following steps:

[0076] Step 1: Wash ginseng, remove impurities, and vacuum freeze-dry;

[0077] Step 2: coarsely pulverizing ginseng, and further pulverizing the coarsely pulverized ginseng with a vibrating rod machine to obtain fine ginseng powder;

[0078] Among them, the process parameters of the vibrating rod machine are: the speed of the rod machine is 800r / min, and the diameter of the white steel rod is 25mm;

[0079] Step 3: preheating the ginseng fine powder to 40°C; meanwhile, controlling the humidity of the ginseng fine powder to be 27%;

[0080] Step 4: Add the ginseng fine powder obtained in step 3 into the boiling granulator, and control the temperature of the boiling granulator to be 65°C;

[0081] Step 5: Add purified water to the fine ginseng powder through a peristaltic pump for granulation, and control the wind speed of the boiling machine to mix the ginseng powder and purified water...

Embodiment 3

[0084] A preparation method of ginseng ultrafine powder, comprising the following steps:

[0085] Step 1: Wash ginseng, remove impurities, and vacuum freeze-dry;

[0086] Step 2: coarsely pulverizing ginseng, and further pulverizing the coarsely pulverized ginseng with a vibrating rod machine to obtain fine ginseng powder;

[0087] Among them, the process parameters of the vibrating rod machine are: the speed of the rod machine is 1000r / min, and the diameter of the white steel rod is 35mm;

[0088] Step 3: preheating the ginseng fine powder to 48°C; meanwhile, controlling the humidity of the ginseng fine powder to be 32%;

[0089] Step 4: Add the ginseng fine powder obtained in step 3 into the boiling granulator, and control the temperature of the boiling granulator to be 70°C;

[0090] Step 5: Add purified water to the fine ginseng powder through a peristaltic pump for granulation, and control the wind speed of the boiling machine to mix the ginseng powder and purified wate...

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Abstract

The invention relates to a ginseng pelletizing technique and specifically discloses a preparation method for an ultra-fine pure ginseng powder tablet. The method comprises the following steps: 1) taking ginseng, washing, removing impurities and performing vacuum freeze drying; 2) roughly crushing ginseng and adopting a vibrating rod type machine for crushing the roughly crushed ginseng in one step, thereby acquiring fine ginseng powder; 3) pre-heating the fine ginseng powder; 4) adding the fine ginseng powder acquired in the step 3) into a boiling pelletizer and controlling the temperature of the boiling pelletizer at 60-80 DEG C; 5) utilizing a peristaltic pump to add purified water into the fine ginseng powder and controlling an air speed of the boiling pelletizer, thereby uniformly mixing the ginseng powder with the purified water; 6) drying till the water content of the ginseng powder is 10-15% after the grain size of the ginseng powder is 15-30 meshes. The preparation method provided by the invention has a good pelletizing effect and is free from phenomena of fragments, powder removal or block falling.

Description

technical field [0001] The invention relates to the granulation technology of ginseng, and specifically discloses a preparation method of ultrafine ginseng powder tablets. Background technique [0002] Ginseng is the dry root and rhizome of Panax ginseng C.A.Meyer. Ginseng has the functions of invigorating vital energy, recovering veins and strengthening the spleen, nourishing the spleen and benefiting the lungs, promoting body fluid and calming the nerves. Has high health care and medicinal value. Moreover, with the acceleration of people's life rhythm, the preservation and traditional usage (such as decoction) of fresh ginseng cannot meet the needs of today's consumers. Processing ginseng into ginseng products is not only convenient for storage, transportation and use, but also improves the utilization of ginseng Rate. Existing ginseng products mainly include dried whole ginseng, sliced ​​ginseng, ginseng capsules or tablets, etc. Among them, ginseng tablets are the mos...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/16A61J3/00
CPCA61J3/00A61K9/1682A61K36/258A61K2236/15A61K2236/17
Inventor 郭秋洋
Owner 中民康达药业股份有限公司
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