Fused protein as well as preparation method and application thereof

A fusion protein and protein technology, applied in the biological field, can solve the problems of late or relapsed patients who cannot be effective, less than 50%, and fail to improve the prognosis of tumor patients, so as to achieve the effect of improving expression yield and accuracy, and improving expression efficiency
CN106749673AActive Publication Date: 2017-05-31张紫寒
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
张紫寒
Publication Date
2017-05-31

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Abstract

The invention provides a fused protein as well as a preparation method and application thereof. The fused protein comprises a CLIC1 protein, a connecting peptide and an Hsp27 (Heat Shock Proteins 27) protein; and the CLIC1 protein is connected with the Hsp27 protein through the connecting peptide. The fused protein provided by the invention can be applied to preparation of medicines for preventing and treating tumors and has the advantages of good specificity, high efficiency of antigens and the like.
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Description

technical field

[0001] The invention belongs to the field of biotechnology, and in particular relates to a fusion protein, a preparation method and an application thereof. Background technique

[0002] Ovarian cancer, cervical cancer and endometrial cancer are three malignant tumors that seriously threaten women's life and health. The five-year survival rate is less than 50%. There are more than 10,000, and there is a clear trend of younger people. The country has widely carried out "two cancer screenings", but it still fails to improve the prognosis of cancer patients. Female reproductive system malignant tumors are malignant tumors that are tackled in my country's medium and long-term scientific and technological development outline plan one. The traditional treatment for malignant tumors of the female reproductive system is surgery, radiotherapy, and chemotherapy, but they only have certain curative effects, and they are not effective for advanced or recurrent patients. At...

Claims

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