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Pharmaceutical composition for treating knee osteoarthritis and preparation method thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems affecting the quality of life of patients, increasing the difficulty of choosing drugs and various therapies, etc.

Inactive Publication Date: 2017-07-04
桑志成
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to the author's clinical observation, among the patients with severe KOA, the elderly are the vast majority, and among them, there are not a few patients who suffer from hypertension, coronary heart disease, diabetes, chronic renal insufficiency and other systemic chronic diseases. This situation not only affects the patients quality of life, while complicating the selection of medications and various therapies

Method used

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  • Pharmaceutical composition for treating knee osteoarthritis and preparation method thereof
  • Pharmaceutical composition for treating knee osteoarthritis and preparation method thereof
  • Pharmaceutical composition for treating knee osteoarthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0075] On the basis of the control group, the above-mentioned treatment group was taken orally with Bushen Jianpi Huoxue Prescription (prepared by the granule pharmacy, one dose per day, twice a day in the morning and evening). 6g, Chuanxiong 10g, Angelica 9g, Stir-fried Paeoniae Alba 20g, Cornus 10g, Achyranthes bidentata 10g, Sangji 10g, Eucommia 10g, Lycium barbarum 15g, Yuanhu 10g, Tangerine peel 9g, Duhuo 9g, clinical addition and subtraction according to the symptoms. Every 7 days as a course of treatment, 2 consecutive courses of treatment, a total of 2 weeks, according to the efficacy of nimodipine statistics.

[0076] Result comparison

[0077] According to the WOMAC scale, after 2 weeks of treatment, 7 cases (21.875%) of the treatment group were ineffective, 25 cases (78.125%) were effective, and 0 cases were markedly effective and cured; 13 cases (46.43%) of the control group were invalid, and 15 cases (53.57% %), markedly effective, recovery from illness are 0 cas...

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Abstract

The invention discloses a pharmaceutical composition for treating knee osteoarthritis and a preparation method thereof. The pharmaceutical composition comprises extracts of the following plant raw materials in parts by weight: 20 to 30 parts of raw radix astragali, 9 to 12 parts of poria cocos, 6 to 9 parts of fried bighead atractylodes rhizome, 3 to 6 parts of honey fried licorice root, 6 to 10 parts of ligusticum wallichii, 6 to 9 parts of Chinese angelica, 10 to 20 parts of fried white peony root, and 10 to 12 parts of pulp of cornus officinalis (or 9 to 15 parts of achyranthes root), and optionally comprises 9 to 12 parts of parasitic loranthus, 10 to 15 parts of eucommia, 10 to 15 parts of wolfberry, and 6 to 9 parts of angelica pubescens. The clinical experiment results show that the pharmaceutical composition has a good curative effect on treating knee osteoarthritis, kidney deficiency, and spleen deficiency.

Description

technical field [0001] The application relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine for treating knee osteoarthritis. Background technique [0002] Knee Osteoarthritis (KOA) is the degeneration and wear of articular cartilage and the formation of osteophytes. The symptoms are knee joint pain, stiffness, deformity and dysfunction, and the symptoms are chronic and progressive. Also known as knee proliferative arthritis, senile arthritis, degenerative arthritis, etc. Epidemiological survey data show that the incidence rate of the disease in middle-aged and elderly people in my country is over 60%, seriously affecting the quality of life of the middle-aged and elderly people, and has become a serious social and economic problem. The purpose of the treatment of this disease is to relieve pain, prevent and delay the progress of the disease, protect joint function, and improve the quality of life. The treatment of Western me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K36/8994A61K36/8905A61K36/8945A61K36/9062A61K36/9064A61K36/8968A61K36/8984A61K36/884A61P19/02A61P29/00
CPCA61K9/0095A61K36/076A61K36/12A61K36/185A61K36/21A61K36/23A61K36/232A61K36/236A61K36/258A61K36/284A61K36/344A61K36/36A61K36/39A61K36/40A61K36/43A61K36/46A61K36/481A61K36/484A61K36/486A61K36/53A61K36/537A61K36/65A61K36/66A61K36/69A61K36/704A61K36/71A61K36/716A61K36/718A61K36/725A61K36/732A61K36/756A61K36/804A61K36/808A61K36/815A61K36/884A61K36/8905A61K36/8945A61K36/8968A61K36/8984A61K36/899A61K36/8994A61K36/9062A61K36/9064A61K2236/331A61K2300/00
Inventor 桑志成王海雄桑灏祺
Owner 桑志成
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