Application of cucuribitane tetracyclic triterpenoids in resisting pulmonary fibrosis
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- CHENGDU BIOPURIFY LTD
- Publication Date
- 2017-07-07
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Abstract
Description
technical field
[0001] The invention belongs to the technical field of prevention and treatment of pulmonary fibrosis, and relates to the application of a cucurbitane-type tetracyclic triterpenoid compound in the preparation of medicines and / or health care products for preventing and / or treating pulmonary fibrosis. Background technique
[0002] Pulmonary fibrosis (PF) is a chronic interstitial lung disease characterized by the infiltration of inflammatory cells such as lymphocytes and macrophages in the pulmonary interstitium, the proliferation of fibroblasts, and the deposition of fibrous connective tissue in the pulmonary interstitium. . Pulmonary fibrosis is caused by various pathogenic factors inside and outside the lung, and is the result of a series of chronic lung injuries or the development of advanced diseases, which seriously endangers human health. The etiology of pulmonary fibrosis includes hereditary immune dysfunction, viral infection, drugs and chemicals, rad...