Method and kit for detecting chromosome abnormality before embryo implantation

A chromosomal abnormality and preimplantation technology, which is applied in the field of preimplantation chromosomal abnormality detection, can solve the problems of large fluctuation of sequencing data, low accuracy, affecting the success rate of IVF implantation and birth rate, etc., so as to improve the results. Accuracy, the effect of improving accuracy
CN107190101APending Publication Date: 2017-09-22ANNOROAD GENE TECH BEIJING +2
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
ANNOROAD GENE TECH BEIJING
Publication Date
2017-09-22

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Abstract

The invention relates to a method for detecting chromosome abnormality before embryo implantation. Specifically, the detection accuracy is improved by adopting the steps of improving a single cell proliferation method and optimizing traditional library construction, and the false positive rate of a karyotype and a CNV is reduced.
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Description

technical field

[0001] The invention belongs to the field of gene detection, and in particular relates to a method suitable for detecting abnormal chromosomes before embryo implantation. Background technique

[0002] In recent years, affected by factors such as modern diet, environment, and living habits, infertility has become more and more common in my country, and the incidence rate in some areas is as high as 15%, which means that 1 in every 10 couples of childbearing age suffers from infertility . Especially after the country abolished the one-child policy and fully liberalized the two-child policy, the long-awaited families, remarried families, families who lost their only child, families who were abducted, and elderly families, etc. , the desire to have another child was widely stimulated, but it was followed by the troubles of infertility, which brought many new propositions to the diagnosis and treatment of infertility.

[0003] Assisted reproductive technology can...

Claims

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