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Anti-wrinkle peptide and cosmetics containing same

A cosmetic, anti-wrinkle technology, applied in the field of non-natural peptides, can solve problems such as insufficient

Active Publication Date: 2020-06-26
温州千瑞生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Simply using moisturizing products for skin care in daily life is obviously not enough to prevent skin aging

Method used

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  • Anti-wrinkle peptide and cosmetics containing same
  • Anti-wrinkle peptide and cosmetics containing same
  • Anti-wrinkle peptide and cosmetics containing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1: Effects on Type I Collagen Synthesis

[0070] Human skin fibroblasts were plated on a 48-well plate at 1 × 10 5 The density of cell / ml was divided into strains, cultured for one day so that the cell confluency reached about 60%, and cultured for another day on FBS-free medium. Prepare FBS-free DMEM medium, divided into four groups A, B, C, and D, add deionized water to group A, add SEQ ID NO:1 peptide to group B so that its concentration is 10ppm, add SEQ ID NO: to group C The peptide of 2 made its concentration 10ppm, and the peptides of SEQ ID NO:1 and SEQ ID NO:2 were added to group D respectively so that their concentrations were 5ppm. Take the cultured human skin fibroblasts, wash them with phosphate buffer, transfer them to the above four groups of media, and store them in CO 2 Incubate for 48 hours in the incubator. To evaluate the expression of procollagen, the culture fluid obtained by the above culture method was quantified using the type I proco...

Embodiment 2

[0074] Embodiment 2: the preparation of anti-wrinkle nutrient solution

[0075] Element Content (weight%) Peptide of the invention (SEQ ID NO: 1) 0.001 Retinol 1.5 Tremella Extract 1.5 Purslane Extract 3.0 1,3 propanediol 3.0 polyglutamic acid 5.0 Rosehip Oil 2.5 Soy Lecithin 3.0 Resveratrol 10.0 carbomer 0.6 Dextran 3.0 lactobionic acid 1.0 Nicotinamide 1.0 purified water Residual amount total 100

[0076] Dissolve carbomer in purified water and add 1,3 propylene glycol, stir evenly, add other components, stir and prepare anti-wrinkle nutrient solution.

Embodiment 3

[0077] Embodiment 3: the preparation of anti-wrinkle nutrient solution

[0078] Element Content (weight%) Peptide of the invention (SEQ ID NO: 2) 0.001 Retinol 0.5 Tremella Extract 0.5 Purslane Extract 2.0 1,3 propanediol 2.0 polyglutamic acid 3.0 Rosehip Oil 1.5 Soy Lecithin 2.0 Resveratrol 5.0 carbomer 0.4 Dextran 2.0 lactobionic acid 2.0 Nicotinamide 2.0 purified water Residual amount total 100

[0079] Dissolve carbomer in purified water and add 1,3 propylene glycol, stir evenly, add other components, stir and prepare anti-wrinkle nutrient solution.

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PUM

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Abstract

The invention relates to anti-wrinkle peptide and cosmetics containing the same. Particularly, the invention discloses SEQ ID NO: 1 and SEQ ID NO: 2 peptides independently applied or combined to resist the wrinkle activity or the cosmetics containing the peptide. The cosmetics comprise, by weight percent, 0.0005-0.001% of SEQ ID NO: 1 and / or SEQ ID NO: 2 peptides, 0.5-2.5% of retinol, 0.5-2.5% of tremella, 2.0-4.0% of purslane extractive, 2.0-4.0% of 1, 3-propylene glycol, 4.0-6.0% of polyglutamic acid, 1.5-3.5% of rosehip seed oil, 2.0-4.0% of soya bean lecithin, 5.0-15.0% of resveratrol, 0.4-0.8% of Carbopol, 2.0-4.0% of glucosan, 1.0-2.0% of lactobionic acid, and 1.0-2.0% of nicotinamide. The cosmetics have the effects of resisting skin wrinkle, preventing skin aging, and the like.

Description

technical field [0001] The present invention relates to non-natural peptides having anti-wrinkle effects and their use in cosmetic and personal care compositions. Background technique [0002] Skin aging is a phenomenon of skin aging caused by natural or unnatural factors. After birth, the skin tissue becomes more and more developed, and its functions are gradually active. When it reaches a certain age, it will begin to degenerate, and this degeneration often proceeds slowly without people's awareness. The growth period of skin tissue generally ends around the age of 25. Some people call this period "the corner of the skin". Since then, growth and aging have proceeded simultaneously, and the elastic fibers of the skin have gradually become thicker. In the early aging period of 40 to 50 years old, the aging of the skin is slow. Significantly slower, although the degree of aging will vary from person to person. [0003] Skin aging is the result of the combined action of the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C07K7/06A61K8/64A61Q19/08
CPCA61K8/64A61Q19/08C07K7/06
Inventor 罗海哨余作取
Owner 温州千瑞生物科技有限公司
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