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Blood lipid reducing oral composition and preparation method thereof

A composition and blood lipid-lowering technology, applied in the field of medicine, can solve the problems of lower patient compliance, inconvenience, and difficulty in clarifying the exact ingredients

Inactive Publication Date: 2017-11-24
孙维伯 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the complex composition of traditional Chinese medicine, it is difficult to determine the exact composition that exerts the medicinal effect, so it is difficult to make an effective sustained-release preparation through pharmaceutical means. Usually, it needs to be used 2-3 times a day, which causes inconvenience to patients and reduces patient compliance.

Method used

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  • Blood lipid reducing oral composition and preparation method thereof
  • Blood lipid reducing oral composition and preparation method thereof
  • Blood lipid reducing oral composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1 Blood lipid-lowering oral liquid and its preparation method

[0037] The prescription of Jiangxuezhi Oral Liquid is shown in the following table:

[0038]

[0039] Preparation:

[0040] 1) Take the prescribed amount of Sophora japonica, safflower, cassia, peppermint, and tangerine peel, respectively pulverize, pass through a 60-mesh sieve, and combine the obtained powders to obtain plant powder;

[0041] 2) Take the prescribed amount of goose pipe stone, crush it, grind it into a fine powder, and pass it through a 100-mesh sieve to obtain mineral powder;

[0042] 3) Add water 6 times the weight of the total weight of raw materials in the prescription to the mineral powder obtained in step 2), heat to boil and decoct for 0.5 hours, then add the plant powder obtained in step 1) to the decoction liquid, boil and decoct for 2.5 hours, Filter and collect the decoction for the first time, and collect the dregs;

[0043] 4) Add water three times the weight of the...

Embodiment 2

[0047] Example 2 Jiangxuezhi granule and preparation method thereof

[0048] The prescription of Jiangxuezhi Granules is shown in the following table:

[0049]

[0050] Preparation:

[0051] 1) Take the prescribed amount of Sophora japonica, safflower, cassia, peppermint, and tangerine peel, respectively pulverize, pass through a 60-mesh sieve, and combine the obtained powders to obtain plant powder;

[0052] 2) Take the prescribed amount of goose pipe stone, crush it, grind it into a fine powder, and pass it through a 100-mesh sieve to obtain mineral powder;

[0053] 3) Add water 6 times the weight of the total weight of raw materials in the prescription to the mineral powder obtained in step 2), heat to boil and decoct for 0.5 hours, then add the plant powder obtained in step 1) to the decoction liquid, boil and decoct for 2.5 hours, Filter and collect the decoction for the first time, and collect the dregs;

[0054] 4) Add water three times the weight of the total wei...

Embodiment 3

[0059] Example 3 Pharmacodynamics Experiment in Oral Liquid for Lowering Blood Fat

[0060] 1. Drugs and Controls

[0061] 1. Experimental drug

[0062] Experimental drug 1: Sophora japonica 1500g, safflower 100g, cassia seed 100g, mint 1000g, tangerine peel 1000g, inulin 70g,

[0063] Goose pipe stone 30g.

[0064] Experimental drug 2: Sophora japonica 1400g, safflower 90g, cassia seed 110g, mint 1050g, tangerine peel 1090g, inulin 90g,

[0065] Goose pipe stone 40g.

[0066] Preparation:

[0067] 1) Take the prescribed amount of Sophora japonica, safflower, cassia, peppermint, and tangerine peel, respectively pulverize, pass through a 60-mesh sieve, and combine the obtained powders to obtain plant powder;

[0068] 2) Take the prescribed amount of goose pipe stone, crush it, grind it into a fine powder, and pass it through a 100-mesh sieve to obtain mineral powder;

[0069] 3) Add water 6 times the weight of the total weight of raw materials in the prescription to the m...

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Abstract

The invention belongs to the field of medicines and particularly relates to blood lipid reducing oral composition and a preparation method thereof. The blood lipid reducing oral composition is prepared from raw materials by weight as follows: 130-160 parts of flos sophorae, 9-12 parts of flos carthami, 9-12 parts of semen cassia, 90-110 parts of mint, 90-110 parts of pericarpium citri reticulatae, 6-10 parts of inulin and 2-5 parts of balanophyllia sp. The composition can be in the form of oral liquid or oral granules and is prepared with an aqueous extraction method. The composition has a higher regulation function on the blood lipid level, has a long-acting effect and is good in safety.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to an oral composition for reducing blood fat and a preparation method thereof. Background technique [0002] Blood lipid is the general term for lipids contained in the blood, mainly including cholesterol, triglycerides, phospholipids, fatty acids, etc. Hyperlipidemia is a disease caused by blood lipid levels exceeding physiological normal values. The disease often occurs in middle-aged and elderly people, and the disease progresses slowly and insidiously. Hyperlipidemia is an independent risk factor for many cardiovascular and cerebrovascular diseases. Elevated blood lipids can lead to a series of systemic diseases, such as hypertension, atherosclerosis, impaired glucose tolerance, diabetes, etc., and can also lead to cerebral hemorrhage, cerebral thrombosis, coronary heart disease, fatty liver, cirrhosis, pancreatitis, and cholelithiasis , peripheral vascular disease, hyper...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/08A61K9/16A61P3/06A61K31/733A61K33/06
CPCA61K9/0095A61K9/1652A61K31/733A61K33/06A61K36/286A61K36/482A61K36/489A61K36/534A61K36/752A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 孙维伯宗绪岩
Owner 孙维伯
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