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Application of lyciumruthenicum murray to preparation of products for reducing uric acid

A black fruit wolfberry and uric acid-lowering technology, applied to the functions of food ingredients, medical preparations containing active ingredients, applications, etc.

Active Publication Date: 2017-12-22
湖州中科院应用技术研究与产业化中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, wolfberry black fruit is widely used as a common edible berry or health food, but there is no research report on the use of wolfberry black fruit or its extracts for reducing uric acid

Method used

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  • Application of lyciumruthenicum murray to preparation of products for reducing uric acid
  • Application of lyciumruthenicum murray to preparation of products for reducing uric acid
  • Application of lyciumruthenicum murray to preparation of products for reducing uric acid

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Embodiment Construction

[0021] The present invention will be further described below in conjunction with specific examples, but the present invention is not limited to the following examples, and the raw materials can be obtained from public commercial channels unless otherwise specified.

[0022] 1. Sample Preparation

[0023] Crude extract of Lycium barbarum polysaccharide: crushed and passed through a 20-mesh sieve → extracted three times with distilled water at 80°C → recovered the filtrate → centrifuged at 3000r10min → supernatant → concentrated by spinning at 70°C → adding edible alcohol (97%) → taking the sediment → press Literature method for protein removal, purification → vacuum drying for 24 hours

[0024] It is determined that the purity of the wolfberry polysaccharide obtained in the present invention is 70%.

[0025] 2. Test animals

[0026] Mice: KM species, SPF grade 18-22g, male, sold by: Hunan Slack Jingda Experimental Animal Co., Ltd., quality inspection unit: Hunan Slack Jingda ...

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Abstract

The invention provides an application of lyciumruthenicum murray polysaccharide to preparation of foods, drugs and healthcare products for reducing uric acid. Researches find that by using lyciumruthenicum murray polysaccharide, blood uric acid can be effectively reduced, xanthine oxidase can also be well inhibited, and therefore a new product is provided for clinical prevention and / or treatment of hyperuricemia.

Description

technical field [0001] The invention relates to a new application of wolfberry black fruit. Background technique [0002] Gout is a group of heterogeneous diseases caused by long-term purine metabolism disorder and elevated blood uric acid causing tissue damage. The clinical features are hyperuricemia (HUA), recurrent gouty acute arthritis, tophi deposition, characteristic chronic arthritis and joint deformities, often involving the kidneys to cause chronic interstitial nephritis and renal uric acid stone formation. The biochemical hallmark of gout is hyperuricemia, which refers to the supersaturation of extracellular fluid with urate. Urate (monosodium uratecrystal, MSU) deposits in the form of crystals in joints and tissues around the joints, causing a series of acute inflammatory reactions, namely gout. It is generally believed that blood uric acid ≧416μmol / L is hyperuricemia, and about 5%-12% of patients with hyperuricemia will develop gout, and those whose blood uric ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P19/06A23L33/125
CPCA23L33/125A23V2002/00A61K31/715A61K36/815A23V2200/30A23V2250/60
Inventor 索有瑞张弓胡娜
Owner 湖州中科院应用技术研究与产业化中心