Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation method of spherical gold nanoparticle

A gold nanoparticle and spherical technology, applied in nanotechnology, metal processing equipment, transportation and packaging, etc., can solve the problems of chemical reagent toxicity, ecological environmental hazards, carcinogenicity, etc., and achieve the effect of simple equipment, low price and convenient operation

Inactive Publication Date: 2017-12-22
UNIV OF SHANGHAI FOR SCI & TECH
View PDF4 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The advantage of the chemical method is that it can quickly synthesize spherical gold nanoparticles. However, in the reaction process, it is generally necessary to introduce chemical reagents as reducing agents and surfactants. Some chemical reagents have certain toxicity and can even cause cancer. The synthesized gold nanoparticles Particles are not suitable for biomedical applications, and the synthesis process will cause harm to the ecological environment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of spherical gold nanoparticle
  • Preparation method of spherical gold nanoparticle
  • Preparation method of spherical gold nanoparticle

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Step 1, dissolving fructose in deionized water to obtain 0.5-1.5 mol / L fructose aqueous solution. In this embodiment, the concentration of the substance amount in the fructose aqueous solution is 1.11 mol / L.

[0025] Step 2, dissolving chloroauric acid crystals in deionized water to form a 0.05-0.12 mol / L chloroauric acid-forming solution. In this embodiment, the concentration of the substance amount in the chloroauric acid aqueous solution is 0.1 mol / L.

[0026] Step 3, washing the glass container used, and rinsing it with deionized water.

[0027] Step 4: inject 25 mL of fructose aqueous solution into the flask, heat to boiling, and keep boiling for 5-15 minutes. In this embodiment, the time to keep the fructose aqueous solution boiling is 15 minutes.

[0028] Step 5: In boiling state, add 80 μL of chloroauric acid solution, react for 5-10 minutes, and keep the pH value of the reaction system between 4.0 and 5.5. In this embodiment, the pH value of the reaction sy...

Embodiment 2

[0043]Step 1, dissolving fructose in deionized water to obtain 0.5-1.5 mol / L fructose aqueous solution. In this embodiment, the concentration of the substance amount in the fructose aqueous solution is 1.11 mol / L.

[0044] Step 2, dissolving chloroauric acid crystals in deionized water to form a 0.05-0.12 mol / L chloroauric acid-forming solution. In this embodiment, the concentration of the substance amount in the chloroauric acid aqueous solution is 0.1 mol / L.

[0045] Step 3, washing the glass container used, and rinsing it with deionized water.

[0046] Step 4: inject 25 mL of fructose aqueous solution into the flask, heat to boiling, and keep boiling for 5-15 minutes. In this embodiment, the time to keep the fructose aqueous solution boiling is 15 minutes.

[0047] Step 5, in boiling state, add 160 μL of chloroauric acid solution, react for 5-10 minutes, and keep the pH value of the reaction system between 4.0 and 5.5. In this embodiment, the pH value of the reaction sy...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention provides a preparation method of a spherical gold nanoparticle. The method is characterized by comprising the following steps: 1, dissolving fructose in deionized water to obtain a fructose water solution; 2, dissolving chloroauric acid crystal in the deionized water to form a chloroauric acid solution; 3, heating the fructose water solution to boiling, then adding the chloroauric acid solution, keeping reaction in the boiling state for 5-10min, and keeping the PH value of the reaction system between 4.0-5.5; 4, obtaining a reaction solution after the reaction is completed; 5, carrying out centrifugal separation on the reaction solution so as to obtain a precipitate; and 6, drying the precipitate so as to obtain the spherical gold nanoparticle. According to the preparation method of the spherical gold nanoparticle, the fructose is used as a reducing agent and a dispersing agent, is convenient and easy to obtain and is free of toxicity, the price of the fructose is low, and the fructose is used as the reducing agent to replace a conventional chemical reagent, no toxic chemical reagent residue is generated on the surface of the obtained spherical gold nanoparticle, and the spherical gold nanoparticle shows an obvious optical signal.

Description

technical field [0001] The invention belongs to the technical field of nanomaterial preparation, and in particular relates to a method for preparing spherical gold nanoparticles. Background technique [0002] Gold nanoparticles are widely used in industrial catalysis, chemical sensing, medical imaging, drug delivery, and biomarking due to their unique optical and electrochemical properties. In the field of biomedicine, nano-gold labels can be obtained after the surface of gold nanoparticles is modified. The label has a spectrum similar to that of gold nanoparticles, and this feature can be used to detect the labeled substance. Spherical gold nanoparticles have a better specific surface area and are more advantageous in the field of catalysis. At present, the rapid synthesis of non-toxic spherical gold nanoparticles with obvious plasmon resonance signals has become a research hotspot in the fields of biomedicine and catalysis. [0003] The traditional synthetic methods of s...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): B22F9/24B82Y40/00B22F1/00
CPCB82Y40/00B22F9/24B22F1/065
Inventor 孙丽王法尹跃超吕鹏程李浩男
Owner UNIV OF SHANGHAI FOR SCI & TECH
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com