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Green plum for treating throat diseases and preparation method of green plum

A throat disease and green plum technology is applied in the field of green plum for treating throat diseases and its preparation, which can solve problems such as excessive treatment and achieve the effect of relieving throat discomfort symptoms.

Active Publication Date: 2017-12-29
SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, viral infection is the main cause of throat diseases. However, clinical patients are still widely treated with antibiotics, and there is a great risk of overtreatment

Method used

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  • Green plum for treating throat diseases and preparation method of green plum
  • Green plum for treating throat diseases and preparation method of green plum
  • Green plum for treating throat diseases and preparation method of green plum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-3

[0022] Step 1), prepare materials according to the formula shown in Table 1, take Gangmei, Platycodon grandiflorum, Radix Arisa, Radix Glycyrrhizae, Radix Achyranthes Radix, Angelica dahurica and Pinellia ginger in parts by weight, add 5 times the quality of water, decoct for 45min, filter, add the filter residue 5 times the quality of water, decoct for 45 minutes, filter, then add 5 times the quality of water to the filter residue, and decoct for 45 minutes;

[0023] Combined and concentrated to obtain the extract, the relative specific density of the extract at 60°C is 1.1;

[0024] Step 2), add sodium benzoate to the extract obtained in step 1), then add peppermint oil, peppermint essence and green plum germ, mix evenly, and after airtight storage for 72 hours, take out the green plum germ and pack it.

experiment example 1

[0036] Experimental example 1 anti-inflammatory effect drug efficacy evaluation

[0037] 1. Purpose of the experiment

[0038] Comparing the anti-inflammatory effect of each embodiment and comparative example (same dosage), provides theoretical basis for its curative effect for treating pharyngitis.

[0039] 2. Experimental principle

[0040] As a chemical inflammatory agent, xylene can cause the release of inflammatory mediators such as histamine, kinin, and fibrinolytic enzymes. The release of these mediators can cause the increase of local capillary permeability and the infiltration of inflammatory cells, resulting in acute exudative inflammatory edema of the ear. The above-mentioned inflammatory response experiment is often used to evaluate the anti-inflammatory effect of the test drug.

[0041] 3. Experimental animals and feeding conditions

[0042] 3.1 Experimental animals

[0043] Grade, breed: SPF grade Kunming mouse

[0044] Animal management: Animals are kept a...

Embodiment 1

[0091] Example 1 The high, medium and low dose groups can inhibit p-xylene-induced ear swelling in mice, and the inhibitory effect is enhanced with the increase of the drug dose. The anti-swelling effect of Comparative Example 1 and Comparative Example 2 that does not contain Araceae and Jiang Pinellia is weaker than that of the dosage group in Example 1, but still has a certain inhibitory effect. Comparative example 4 and comparative example 5 are weaker than comparative example 1 in inhibiting swelling.

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PUM

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Abstract

The invention discloses green plums for treating throat diseases and a preparation method of the green plums. The preparation method comprises the following steps: 1) boiling the following components in parts by weight for three times: 430-530 parts of holly roots, 580-710 parts of achyranthes aspera, 430-530 parts of ginger processed pinellia, 430-530 parts of rhizoma arisaematis, 800-1000 parts of platycodon grandiflorum, 1400-1700 parts of licorice root and 430-530 parts of radix angelicae, filtering, combining filtrate, and concentrating so as to obtain an extract, wherein the relative density of the extract at 60 DEG C is not less than 1.1; 2) uniformly mixing the extract with 1-3 parts of a preservative, 80-100 parts of dementholized peppermint oil, 80-100 parts of mint essence and 16000-20000 parts of green plum blanks, sealing and storing for 72 hours, and packaging the green plum blanks, thereby obtaining the green plums. The green plums disclosed by the invention are relatively good in treating throat discomfort.

Description

technical field [0001] The invention relates to the field of treating throat diseases, in particular to greengage for treating throat diseases and a preparation method thereof. Background technique [0002] Throat disease is a common upper respiratory system disease, mostly caused by upper respiratory tract infection. Chronic rhinitis, acute and chronic tonsillitis. Current studies believe that the main etiology is virus, bacteria and non-infectious factors (such as mouth breathing, allergic reaction, gastroesophageal reflux, smoking, alcohol, high temperature, dust, smoke, irritating gas, etc.). Among them, viral infection is the main cause of throat diseases. However, clinical patients are still widely treated with antibiotics, and there is a great risk of overtreatment. Contents of the invention [0003] In summary, it is necessary for the present invention to provide a greengage for treating throat diseases, which can effectively relieve the symptoms of sore throat a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P11/04A61P29/00A61P31/00A23L19/00A23L33/105
CPCA23V2002/00A61K9/0056A61K36/185A61K36/21A61K36/232A61K36/346A61K36/484A61K36/736A61K36/8884A61K36/8888A61K2236/331A61K2236/39A23L19/03A23L33/105A61K2300/00A23V2200/314A23V2250/21
Inventor 伍俊妍邱凯锋刘春霞余晓霞李国成李钦海
Owner SUN YAT SEN MEMORIAL HOSPITAL SUN YAT SEN UNIV
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