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Feed additive capable of improving piglet immunity

A feed additive and immunity technology, applied in the field of piglet feed additives, can solve problems that have not yet been seen, achieve the effects of no toxic side effects, improve piglet immunity, and significant curative effect

Active Publication Date: 2018-01-19
播恩集团股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0019] At present, there is no literature report on the combination of oxymatrine and bletilla striata polysaccharide as a feed additive to improve piglet immunity

Method used

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  • Feed additive capable of improving piglet immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1, the extraction of bletilla striata polysaccharide

[0041] Bletilla striata tuber dried products were crushed, sieved, dried, added 20 times the volume of distilled water, refluxed at 60°C for 4 hours, repeated extraction once, and combined the two extracts. Centrifuge at 5000rpm for 10min, take the supernatant and filter it with suction, concentrate under reduced pressure at 70°C to a smaller volume, add 3 times the volume of absolute ethanol to precipitate, dissolve the precipitate in the minimum volume of water, and deproteinize it by Sevag method until it is detected by Coomassie brilliant blue G-250 method No protein was detected. The obtained solution was dialyzed with distilled water for 5 days, the relative molecular mass cut-off of the dialysis bag was 8000-10000, and vacuum freeze-dried.

Embodiment 2

[0042] Embodiment 2, the preparation of feed additive

[0043] Take 5 parts by weight of oxymatrine and 5 parts by weight of Bletilla striata polysaccharide prepared in Example 1, and mix them to make feed additive S1 with a weight ratio of oxymatrine and Bletilla striata polysaccharide in a 1:1 weight ratio.

[0044] Take 4 parts by weight of oxymatrine and 6 parts by weight of Bletilla striata polysaccharide prepared in Example 1, and mix them to make feed additive S2 with a weight ratio of oxymatrine and Bletilla striata polysaccharide of 2:3.

[0045] Take 1 part by weight of oxymatrine and 9 parts by weight of Bletilla striata polysaccharide prepared in Example 1, and mix them to prepare feed additive S3 with a weight ratio of oxymatrine and Bletilla striata polysaccharide in a weight ratio of 1:9.

Embodiment 3

[0046] Embodiment 3, the application of feed additive of the present invention in improving piglet immunity

[0047] 1. Experimental animals and grouping treatment

[0048] Select 20-day-old piglets with clinical health and similar body weight, take blood samples to detect the maternal antibody level of swine fever, select 120 piglets with similar antibody levels, and divide them into 6 groups at random, i.e. Chinese medicine composition groups 1-3 of the present invention (Example 1). 2 Prepared feed additives S1-S3), oxymatrine group, bletilla striata polysaccharide group and control group, 20 piglets in each group. At the age of 21 days, the rabbits were immunized with attenuated swine fever rabbit vaccine. At the age of 27-31 days, add the above-mentioned feed additives according to 1% of the total weight of the feed in the diets of the S1-S3 Chinese medicine composition group, oxymatrine group, and bletilla striata polysaccharide group (the total amount of active ingredi...

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PUM

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Abstract

The invention relates to a feed additive capable of improving the piglet immunity, wherein the weight ratio of the active component oxymatrine to bletilla striata polysaccharide is (1:10)-(10:1). Compared with common feed additives, the piglet feed additive provided by the invention has the advantages that a preparation method is simple, the combination is reasonable, the curative effect is obvious, and the piglet immunity can be obviously improved. Because the additive does not contain Western medicine components, the feed additive is free of toxic or side effect and free of drug resistance.

Description

technical field [0001] The invention relates to the field of feed, in particular to a feed additive for piglets. Background technique [0002] For a long time, the high incidence of diseases in weaned piglets has been an important reason that has seriously plagued the development of my country's pig industry. After the piglets are weaned, due to the interruption of breast milk and sudden changes in the environment, feed, etc., the dysfunction of various systems and the decline of the body's immunity are caused. , circovirus, etc.), causing serious consequences such as high morbidity and mortality in piglets after weaning. [0003] At present, foreign countries mainly prevent and control piglet weaning syndrome by adjusting the composition of diets (such as high-nutrition, high-adaptability piglet weaning feed), temperature control and other environmental controls. In China, secondary infection is mainly controlled by adding antibiotics to feed, but it is easy to cause drug...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K20/132A23K20/142A23K20/163A23K20/174A23K50/30A23K50/60
Inventor 郭丽黄蓉卢秋咏梁冬霞邹新华
Owner 播恩集团股份有限公司