Pharmaceutical composition formula for treating cervicitis and use of pharmaceutical compound preparation

A composition and drug technology, applied in the field of medicine, can solve the problems of poor curative effect and difficult complete cure of cervicitis, and achieve the effect of not easy chemical action, promoting proliferation, differentiation and secretion, and promoting regeneration

Inactive Publication Date: 2018-01-19
GUILIN HAOXIN TECH SERVICE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In view of the above problems, the present invention provides a formulation and application of a pharmaceutical composition for treating cervicitis. The formula

Method used

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  • Pharmaceutical composition formula for treating cervicitis and use of pharmaceutical compound preparation
  • Pharmaceutical composition formula for treating cervicitis and use of pharmaceutical compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Formula composition: dracaena polyphenols 5g, sucralfate 7.5g, silica nanoparticles 50g, carbomer 1g, methyl p-hydroxybenzoate 0.08g, triethanolamine 0.2g, propylene glycol 0.5g, deionized water plus to 200g.

[0032] Preparation steps: weigh 1 g of carbomer, disperse it in 100 g of deionized water, and swell for 24 hours, then add triethanolamine to adjust the pH value to 4.0-5.0 to obtain solution A; dissolve 0.08 g of methyl p-hydroxybenzoate and 0.5 g of propylene glycol in an appropriate amount of warm water , Dracaena polyphenols 5g, sucralfate 7.5g, silicon dioxide nanoparticles 50g, and slowly add in the solution A, add deionized water to 200g, stir evenly to obtain the drug gel.

Embodiment 2

[0034] Formula composition: dracaena polyphenol 4g, sucralfate 6g, silica nanoparticles 30g, carbomer 0.8g, methyl p-hydroxybenzoate 0.06g, triethanolamine 0.2g, propylene glycol 0.4g, deionized water plus to 200g.

[0035] Preparation steps: weigh 0.8 g of carbomer, disperse it in 100 g of deionized water and swell for 24 hours, then add triethanolamine to adjust the pH value to 4.0-5.0 to obtain solution A; dissolve 0.06 g of methyl p-hydroxybenzoate and 0.4 propylene glycol in appropriate amount of warm water g. Add 4 g of dragon's blood polyphenols, 6 g of sucralfate, and 30 g of silicon dioxide nanoparticles into solution A slowly, add deionized water to 200 g, and stir evenly to obtain a drug gel.

Embodiment 3

[0037] Formula composition: dragon's blood polyphenol 3g, sucralfate 4g, silica nanoparticles 20g, carbomer 0.6g, methyl p-hydroxybenzoate 0.04g, triethanolamine 0.2g, propylene glycol 0.3g, deionized water plus to 200g.

[0038] Preparation steps: weigh 0.6 g of carbomer, disperse it in 100 g of deionized water, and swell for 24 hours, then add triethanolamine to adjust the pH value to 4.0-5.0 to obtain solution A; dissolve 0.04 g of methyl p-hydroxybenzoate and 0.3 propylene glycol in appropriate amount of warm water g, 3g of dragon's blood polyphenol, 4g of sucralfate, and 20g of silicon dioxide nanoparticles were slowly added to solution A, and deionized water was added to 200g, and the drug gel was obtained by stirring evenly.

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Abstract

The invention relates to a pharmaceutical composition formula for treating cervicitis and use of the composition formula. The composition formula contains the following effective active components: silicon dioxide nanoparticles, sucralfate and sanguis draconis polyphenol. The silicon dioxide nanoparticles, sucralfate and the sanguis draconis polyphenol are combined and are used as pharmaceutical active components, and the cervicitis is treated through local medication, so that a synergistic interaction is achieved, the curing rate of the cervicitis is high, and the cervicitis is unlikely to relapse.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to the formulation and application of a pharmaceutical composition for treating cervicitis. Background technique [0002] The female cervix is ​​weakly acidic under normal circumstances, and the pH of vaginal secretions is pH=3.8-4.5, which is also acidic, which can be used to sterilize and prevent cervical infection. However, germs that are harmful to the body can also grow in a weakly alkaline environment, so when the cervix is ​​weakly alkaline, these harmful bacteria will concentrate in the cervix. When around the cervix, endotoxins and exotoxins are secreted, and these toxins dissolve the skin surface of the cervix, thus producing related secretions. [0003] In cervicitis, it is usually found that there is yellow thick secretion flowing from the cervix, and the columnar epidermis on the cervix is ​​also particularly fragile and prone to redness, swelling and cong...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61P15/00A61K33/00A61K31/7024A61K33/06
Inventor 钟传新王君
Owner GUILIN HAOXIN TECH SERVICE
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