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A traditional Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs and its preparation method

A chemotherapy drug and phlebitis technology, applied in the field of medicine, to achieve the effects of reasonable preparation process, easy cleaning, and good coating properties

Active Publication Date: 2020-08-25
BEIJING CANCER HOSPITAL PEKING UNIV CANCER HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to overcome the deficiencies and problems existing in the curative effect of existing traditional Chinese medicine preparations, the present invention provides a kind of Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs, and compared with the preparation method of traditional ointment, it develops a more reasonable and more active ingredient. Concentrated new preparation process in order to obtain better curative effect

Method used

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  • A traditional Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs and its preparation method
  • A traditional Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs and its preparation method
  • A traditional Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs and its preparation method

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Embodiment 1

[0039]A water-soluble base ointment for treating phlebitis caused by chemotherapy drugs, which is made of active ingredients and a water-soluble base, and the active ingredients are made of the following raw materials by weight: 20 parts of comfrey, 30 parts of raw Burnet , 30 parts of raw land, 20 parts of gardenia, 500 parts of rhubarb, 20 parts of Scutellaria baicalensis, 15 parts of borneol, 20 parts of dried blood, and 15 parts of dairy products; the water-soluble matrix includes the following raw materials in parts by weight: carboxymethyl cellulose 40 parts of plain sodium, 25 parts of carbomer, 6 parts of glycerol, 4008 parts of polyethylene glycol, 3 parts of azone, 0.15 parts of benzalkonium chloride;

[0040] The preparation method of described ointment comprises the steps:

[0041] a) Weigh each raw medicinal material according to parts by weight, remove impurities, pulverize, pass through an 80-mesh sieve, and set aside;

[0042] b) Take the volatile oil that has...

Embodiment 2

[0049] A water-soluble base ointment for treating phlebitis caused by chemotherapy drugs, which is made of active ingredients and a water-soluble base, and the active ingredients are made of the following raw materials by weight: 15 parts of comfrey, 20 parts of raw Burnet , 25 parts of raw land, 15 parts of gardenia, 400 parts of rhubarb, 10 parts of Scutellaria baicalensis, 10 parts of borneol, 15 parts of dried blood, and 10 parts of milk making; the water-soluble matrix includes the following raw materials in parts by weight: carboxymethyl cellulose 30 parts of plain sodium, 20 parts of carbomer, 5 parts of glycerol, 4006 parts of polyethylene glycol, 3 parts of azone, 0.15 parts of benzalkonium chloride;

[0050] The preparation method of described ointment comprises the steps:

[0051] a) Weigh each raw medicinal material according to parts by weight, remove impurities, pulverize, pass through an 80-mesh sieve, and set aside;

[0052] b) Take the volatile oil that has n...

Embodiment 3

[0059] A water-soluble base ointment for treating phlebitis caused by chemotherapy drugs, which is made of active ingredients and a water-soluble base, and the active ingredients are made of the following raw materials by weight: 25 parts of comfrey, 35 parts of raw Burnet , 30 parts of raw land, 25 parts of gardenia, 550 parts of rhubarb, 15 parts of Scutellaria baicalensis, 20 parts of borneol, 30 parts of dried blood, and 25 parts of milk making milk; the water-soluble matrix includes the following raw materials in parts by weight: carboxymethyl cellulose 40 parts of plain sodium, 30 parts of carbomer, 8 parts of glycerol, 4007 parts of polyethylene glycol, 6 parts of azone, 0.25 parts of benzalkonium chloride;

[0060] The preparation method of described ointment comprises the steps:

[0061] a) Weigh each raw medicinal material according to parts by weight, remove impurities, pulverize, pass through an 80-mesh sieve, and set aside;

[0062] b) Take the volatile oil that ...

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating phlebitis caused by chemotherapeutic drugs and a preparation method thereof. According to the traditional Chinese medicine preparation, with radix et rhizoma rhei as a principal drug, the radix et rhizoma rhei is used for cooling blood and dissipating blood stasis; through coordination of radix rehmanniae, radix arnebiae, radix sanguisorbae and the radix et rhizoma rhei, the effects of cooling the blood and relieving the pain are achieved so as to fulfill the aim of decreasing swelling to relieve the pain; due tosanguis draxonis and frankincense myrrh, recovery of damage of blood vessels and skin can be improved, and granulation promotion and pain stop are achieved; due to radix scutellariae and borneol, pathogenic heat is cleared away and dissipated, and the heat is cleared away and the pain is relieved, so that the effects of cooling the blood and removing toxic substances and decreasing the swelling and relieving the pain are achieved together. According to the traditional Chinese medicine preparation, swelling and pain of blood vessels and skin, bruise, scleroma and the like caused by extravasation of intravenous injection chemotherapeutic drugs can be effectively treated, the curative effect of the traditional Chinese medicine preparation disclosed by the invention is obviously superior to existing drugs in the same class. According to the invention, a preparation process and a dosage form also are improved, so that the curative effect of the traditional Chinese medicine preparation is further improved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine preparation for treating phlebitis caused by chemotherapy drugs and a preparation method thereof. Background technique [0002] Phlebitis caused by intravenous infusion of chemotherapy drugs is often manifested as pain along the direction of the blood vessel. In severe cases, induration and swelling of the surrounding skin tissue may occur. The chemical inflammatory reaction of the local vein wall and soft tissue is mostly caused by drug stimulation of blood vessels. [0003] According to modern medicine, the pathogenesis of chemotherapy-induced phlebitis mainly includes the direct toxic effect of chemotherapy drugs on normal cells, the acidic or alkaline plasma pH caused by drugs, which interferes with the normal metabolism and function of the vascular intima, and the local Allergic reactions, long-term infusion or intravenous injecti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/896A61K36/889A61K9/06A61P9/14A61K31/045
CPCA61K9/0014A61K9/06A61K31/045A61K36/30A61K36/324A61K36/328A61K36/539A61K36/708A61K36/739A61K36/744A61K36/804A61K36/889A61K36/896A61K47/38A61K2236/331A61K2236/333A61K2236/39A61K2236/53A61K2300/00
Inventor 李萍萍
Owner BEIJING CANCER HOSPITAL PEKING UNIV CANCER HOSPITAL