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Sterilization method for traditional Chinese medicine ultramicro powder

A sterilization method and technology of traditional Chinese medicine powder, which is applied in the field of sterilization of ultrafine traditional Chinese medicine powder and 60Co-γ ray irradiation sterilization of ultrafine traditional Chinese medicine powder, which can solve the loss of volatile and heat-sensitive substances and require strict sterilization equipment , Not suitable for large-scale production and other issues, to achieve the effect of ensuring drug efficacy, high sterilization efficiency and fast speed

Inactive Publication Date: 2018-04-06
湖南省核农学与航天育种研究所
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  • Abstract
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Problems solved by technology

The dry heat sterilization method is easy to operate and the equipment is simple, but the required temperature is high, the energy consumption is large, and it is difficult to achieve complete sterility. The volatile substances and heat-sensitive substances in traditional Chinese medicine are seriously lost, which greatly affects the medicinal properties of the medicine.
The sterilization effect of moist heat sterilization is ideal, but the requirements for sterilization equipment are strict, and the loss of volatile and heat-sensitive substances is serious
The microwave sterilization method has strong penetrating power, rapid sterilization, and less destructive power to the active ingredients, but the required equipment is expensive, and it is not suitable for large-scale production
In recent years, although there have been many studies on radiation sterilization in pharmaceutical processing, most of them are directly sterilized by radiation, and it is generally believed that radiation sterilization of drugs will cause the loss of active ingredients, reduce the efficacy, and There is a certain danger

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  • Sterilization method for traditional Chinese medicine ultramicro powder
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  • Sterilization method for traditional Chinese medicine ultramicro powder

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Embodiment 1

[0029] A kind of sterilization method of ultrafine Chinese medicine powder of the present invention, this ultrafine Chinese medicine powder is ultrafine Radix Notoginseng powder, and sterilization method comprises the following steps:

[0030] (1) Carry out impurity removal, deworming, sieving and drying pretreatment on raw material superfine notoginseng powder. The particle size of the superfine Panax notoginseng powder is between 4.0 and 9.0 μm. It is off-white powder with a fine powder feel, normal appearance, and no insects or impurities. The superfine notoginseng powder is dried using LYSD-881 tunnel blast oven, the temperature is 55°C, the time depends on the moisture content, and the final moisture content after drying is about 8%.

[0031] (2) the superfine notoginseng powder obtained in step (1) is sealed in a PE bag, and the thickness is 40cm (all can be less than 60cm). The main purpose of bagging and sealing is to prevent the superfine notoginseng powder from bein...

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Abstract

The invention discloses a sterilization method for traditional Chinese medicine ultramicro-powder which is pseudo-ginseng ultramicro-powder. The sterilization method includes steps of: performing pretreatment and bag-sealing package to a pseudo-ginseng ultramicro-powder raw material, and performing irradiation sterilization with Co-60-gamma radioactive source to prepare the sterilized pseudo-ginseng ultramicro-powder. The method is carried out at normal temperature and is free of heating and addition of any additives, has almost no influence on extracts of the pseudo-ginseng ultramicro-powder,content of notoginsenoside, components such as amino acids and minerals, and hemostasis function of the pseudo-ginseng ultramicro-powder. The method can completely sterilize the ultramicro-powder quickly, has simple operations, is convenient to carry out continuously at large scale, and completely solves problems of sanitary and safety of traditional Chinese medicine ultramicro-powders and avoidsloss of the active components during conventional sterilization process of the traditional Chinese medicine ultramicro-powder.

Description

technical field [0001] The invention belongs to the field of sterilization of ultrafine traditional Chinese medicine powder, and relates to a method for sterilization of ultrafine traditional Chinese medicine powder, in particular to a method for the sterilization of ultrafine traditional Chinese medicine powder. 60 Co-γ-ray irradiation sterilization method. Background technique [0002] For a long time, Panax notoginseng has always been a very good Chinese medicinal material. It has the effects of stopping bleeding, dispelling blood stasis, and relieving pain. It is extremely versatile and can be used to treat various internal and external bleeding such as traumatic bleeding, blood stasis, gastric bleeding, and hematuria It also has the functions of dilating blood vessels, dissolving thrombus, improving microcirculation, preventing and treating cardiovascular and cerebrovascular diseases such as hyperlipidemia, increased cholesterol, coronary heart disease, angina pectoris,...

Claims

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Application Information

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IPC IPC(8): A61L2/08
Inventor 罗志平孟兰贞李俊杰李文革赵静
Owner 湖南省核农学与航天育种研究所
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