Paraben-based cosmetic preservative and preparation method and application thereof
A technology of paraben and methyl paraben, which is applied in the field of cosmetic preservatives based on paraben and preparation thereof, and can solve the problems of skin irritation and the like
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[0017] The present invention also provides a kind of preparation method of cosmetic antiseptic based on paraben ester, and this preparation method comprises:
[0018] 1) Dissolving phenoxyethanol in a solvent to obtain a phenoxyethanol solution;
[0019] 2) Adding methylparaben and ethylparaben to phenoxyethanol solution to obtain a cosmetic preservative based on paraben;
[0020] Wherein, the weight ratio of phenoxyethanol, methylparaben, ethylparaben and solvent is 35-45:25-33:20-30:50-60.
[0021] In the above preparation method, the content of each component can be selected in a wide range, but in order to make the prepared preservative have excellent antibacterial effect, preferably, phenoxyethanol, methylparaben, ethylparaben The weight ratio to the solvent is 38-42:28-30:25-28:55-58.
[0022] In the above preparation method, the specific type of solvent can be selected in a wide range, but in order to make the prepared preservative have excellent antibacterial effect,...
Embodiment 1
[0029] 1) Dissolve phenoxyethanol in the solvent (propylene glycol) by stirring (stirring speed is 2000rpm, stirring time is 3h) to obtain phenoxyethanol solution;
[0030] 2) Add methylparaben and ethylparaben to the phenoxyethanol solution in sequence, and perform ultrasonic oscillation (ultrasonic frequency: 60KHz, oscillation time: 1h) to prepare paraben-based cosmetic preservative A1 Wherein, the weight ratio of phenoxyethanol, methylparaben, ethylparaben and solvent is 35:25:20:50.
Embodiment 2
[0032] 1) Dissolve phenoxyethanol in the solvent (1,3-butanediol) by stirring (stirring speed is 3000rpm, stirring time is 5h) to prepare phenoxyethanol solution;
[0033] 2) Add methylparaben and ethylparaben to the phenoxyethanol solution in sequence, and perform ultrasonic oscillation (ultrasonic frequency 60-80KHz, oscillation time 1-2h) to prepare paraben-based Cosmetic preservative A2; wherein, the weight ratio of phenoxyethanol, methylparaben, ethylparaben and solvent is 45:33:30:60.
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