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Preparation method of ointment capable of improving osteoarticular cell metabolism and activating osteoarticular cells

A metabolism, bone and joint technology, used in medical preparations containing active ingredients, bone diseases, ointment delivery, etc., to accelerate regeneration and lymphatic circulation, reduce intraosseous pressure, relieve pain and swelling.

Inactive Publication Date: 2018-05-29
李佳峰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Whether in China or other European and American countries, the treatment of osteoarthritis will have a huge economic burden for patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] It is characterized by the following steps, wherein, the weight ratio of raw materials is: (1) 5 parts of Chuanxiong extract, (2) 15 parts of Passepartout extract, (3) 10 parts of Shenjincao extract, (4) Sanlong 12 parts of extract, (5) 5 parts of clove oil, (6) 4 parts of cinnamon oil, (7) 8 parts of Speranza extract, (8) 5 parts of safflower extract, (9) 8 parts of notopterygium extract , (10) 4 parts of lovage extract, (11) 3 parts of Chuanwu extract, (12) 8 parts of allantoin, (13) 10 parts of cassia twig extract, (14) acryloyldimethyl taurine Ammonium 0.5 part, (15) Polysorbate-80 0.5 part, (16) Isohexadecane 0.1 part, (17) Glycerin 0.1 part, (18) Methylparaben 0.03 part, (19) Sodium hyaluronate 0.5 parts, (20) vanillyl butyl ether 0.1 parts;

[0024] The steps described are as follows:

[0025] A. After mixing (1)-(13) evenly according to the above ratio, the conditioning material is obtained;

[0026] B. Mix the raw materials (14)-(16) to obtain a mixture. Acc...

Embodiment 2

[0029] It is characterized by the following steps, wherein, the weight ratio of raw materials is: (1) 6 parts of Chuanxiong extract, (2) 16 parts of Passepartout extract, (3) 11 parts of Shenjincao extract, (4) Sanlong 13 parts of extracts, (5) 7 parts of clove oil, (6) 5 parts of cinnamon oil, (7) 9 parts of Speranza extract, (8) 6 parts of safflower extract, (9) 9 parts of notopterygium extract , (10) 5 parts of Lovage Extract, (11) 4 parts of Aconitum Aconitum Extract, (12) 9 parts of Allantoin, (13) 11 parts of Guizhi Extract, (14) Acryloyldimethyltaurine 0.6 parts of ammonium, (15) 0.7 parts of polysorbate-80, (16) 0.2 parts of isohexadecane, (17) 0.2 parts of glycerin, (18) 0.04 parts of bis(hydroxymethyl) imidazolidinyl urea, ( 19) Sodium hyaluronate 1 part, (20) CI 19140 0.2 part;

[0030] Making step is the same as embodiment 1

Embodiment 3

[0032] It is characterized by the following steps, wherein, the weight ratio of raw materials is: (1) 8 parts of Chuanxiong extract, (2) 17 parts of Passepartout extract, (3) 12 parts of Shenjincao extract, (4) Sanlong 15 parts of extracts, (5) 8 parts of clove oil, (6) 6 parts of cinnamon oil, (7) 10 parts of Speranza extract, (8) 7 parts of safflower extract, (9) 10 parts of notopterygium extract , (10) 6 parts of Lovage Extract, (11) 5 parts of Aconitum Aconitum Extract, (12) 10 parts of Allantoin, (13) 12 parts of Guizhi Extract, (14) Acryloyldimethyltaurine Ammonium 0.8 part, (15) Polysorbate-80 0.8 part, (16) Isohexadecane 0.3 part, (17) Glycerin 0.3 part, (18) Bis(hydroxymethyl) imidazolidinyl urea 0.05 part, ( 19) Sodium hyaluronate 1.5 parts, (20) CI 19140 0.3 parts;

[0033] Making step is the same as embodiment 1

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PUM

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Abstract

The invention discloses a preparation method of ointment capable of improving osteoarticular cell metabolism and activating osteoarticular cells. The ointment is prepared from raw materials in parts by weight as follows: 4-8 parts of a rhizoma chuanxiong extract, 15-17 parts of a fructus liquidambaris extract, 10-12 parts of a herba lycopodii extract, 12-15 parts of a rhizoma sparganii extract, 5-8 parts of clove oil, 4-6 parts of cinnamon oil, 8-10 parts of a garden balsam stem extract, 5-7 parts of a flos carthami extract, 8-10 parts of a rhizoma seu radix notopterygii extract, 4-6 parts ofa radix angelicae pubescentis extract, 3-5 parts of a radix aconiti extract, 8-10 parts of allantoin, 10-12 parts of a cassia twig extract, 0.5-0.8 parts of ammonium acryloyldimethyltaurate, 0.5-0.8 parts of polysorbate-80, 0.1-0.3 parts of isohexadecane, 0.1-0.3 parts of glycerin and 0.5-1.5 parts of sodium hyaluronate. The ointment can promote stem cells to grow quickly to have the function of improving joints.

Description

technical field [0001] The invention relates to a preparation method of bone joint cell paste, in particular to a preparation method of improving bone joint cell metabolism and activating bone joint cell paste. Background technique [0002] Osteoarthritis (OA) is a painful chronic disease that can severely impact patients' quality of life. And so far there is no effective treatment for this chronic disease. Globally, the number of people with osteoarthritis is increasing and is expected to reach 130 million by 2050. Whether in China or other European and American countries, the treatment of osteoarthritis will impose a huge economic burden on patients. [0003] Stem cells are a population of multipotent endogenous progenitor cells capable of differentiating into musculoskeletal tissues with well-defined immunomodulatory roles, mainly through paracrine signaling to control inflammatory responses. In recent years, Chinese medical academic journals ("Guangdong Medicine", Sep...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/902A61K9/06A61K47/36A61K47/26A61K47/20A61P19/02A61P29/00A61K31/4166
CPCA61K9/06A61K31/4166A61K36/11A61K36/185A61K36/232A61K36/236A61K36/237A61K36/286A61K36/47A61K36/54A61K36/61A61K36/714A61K36/902A61K47/20A61K47/26A61K47/36A61K2300/00
Inventor 李佳峰
Owner 李佳峰
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