Detection device and application thereof

A detection device and micro-channel technology, applied in measuring devices, material analysis through electromagnetic means, instruments, etc., can solve the problems of limited test accuracy, inability to test multiple test items, single test item of blood glucose test strips, etc., and achieve improvement Convenience, the effect of avoiding the risk of clogging

Active Publication Date: 2018-06-05
SHENZHEN GOLDSITE DIAGNOSTICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The blood glucose test strip test adopts the principle of electrochemistry, which has the advantages of high precision and small instrument; however, the blood glucose test strip is a single test ite

Method used

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  • Detection device and application thereof
  • Detection device and application thereof
  • Detection device and application thereof

Examples

Experimental program
Comparison scheme
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Embodiment 1

[0066] Example 1 with pH and pO 2 Electrode sensor is taken as an example to describe the present invention in detail

[0067] pH electrode preparation:

[0068] The pH electrode structure is: Ag / AgCl internal reference / electrolyte layer / ion selective membrane layer;

[0069] The solid electrolyte used in the present invention uses PVP or PVA as a solid phase carrier, adds 100-500mM NaCl or KCl as a supporting electrolyte, and simultaneously adds PBS or Hepes as a pH buffer reagent;

[0070] The ion selective membrane is composed of: PVC (66% by wt.%) + NPOE (33% by wt.%) + H + carrier 1 (1% by wt.%)

[0071] Each sensor film layer is evenly coated on the circular area of ​​the sensor chip by means of Microdispensing.

[0072] pO 2 Electrode preparation:

[0073] pO 2 The electrode structure is: electrolyte membrane layer / gas permeable membrane layer;

[0074] The electrolyte layer uses hydrophilic gel as a solid phase support carrier, such as PEG, trehalose, D4, etc., ...

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Abstract

The invention relates to the field of in-vitro diagnosing medical appliances, particularly relates to a detection device, as well as a preparation method and application thereof, and further disclosesa POCT diagnostic card. The diagnostic card integrates a calibration reagent, a reagent valve, an electrode array chip, a waste liquid storage cavity and the like, so that reagent sampling is not required in the detecting process, no extra medical waste is generated, and all fluids and pipelines are integrated on the test card, so that use convenience is greatly improved, and the risk of fluid path blockage of an instrument can be avoided. The diagnostic card applies the electrochemical principle, can be used for performing in-vitro diagnosis on patients and analyzing certain biological and chemical substances in human blood samples, and can be applied to multiple medical diagnosing fields, such as biochemical item tests, blood-qi item tests, metabolin tests, hematological tests, clottingtests and immune tests (cardiac markers and the like).

Description

technical field [0001] The invention relates to the field of in vitro diagnostic medical devices, in particular to a detection device and its application. Background technique [0002] POCT rapid diagnostic technology has become a development trend in medical diagnosis, and there are many corresponding diagnostic cards or diagnostic test strips; mainly including colloidal gold test strips, immunofluorescence test strips, blood glucose test strips, etc., and their common feature is one-time use. [0003] Colloidal gold test paper and immunofluorescence test paper have low measurement accuracy due to the limitation of the test methodology adopted by the instrument, and are generally qualitative or semi-quantitative measurements. [0004] In electrochemical technology, the signal response, transmission and acquisition can be realized through pure hardware circuits. With the rapid development of PCB manufacturing technology, the size of a multi-channel electrochemical tester can...

Claims

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Application Information

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IPC IPC(8): G01N27/416
CPCG01N27/416
Inventor 刘玲陈明峰钱生君
Owner SHENZHEN GOLDSITE DIAGNOSTICS
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