Composition for treating hyperostosis and joint arthralgia spasm pain as well as preparation method of composition

A technology for arthralgia and bone hyperplasia, applied in the direction of drug combination, non-active ingredient medical preparations, medical preparations containing active ingredients, etc., can solve problems such as easy pollution of the environment, easy sticky skin, easy allergies, etc. Achieve huge economic benefits, do not pollute clothes, and have good safety effects

Inactive Publication Date: 2018-06-29
GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional production process of black plaster is complicated. When refining at high temperature, the active ingredients are not completely extracted and easily destroyed, the quality of the preparation is difficult to control, and the oil-immersed medicinal re

Method used

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  • Composition for treating hyperostosis and joint arthralgia spasm pain as well as preparation method of composition
  • Composition for treating hyperostosis and joint arthralgia spasm pain as well as preparation method of composition
  • Composition for treating hyperostosis and joint arthralgia spasm pain as well as preparation method of composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Prescription: Red soil Poria, safflower, Qingfengteng, raw shrug, iron chopsticks, Jianxuefei each 20g, Aracea, Pinellia, Aconitum each 2g, blood dried out, hippocampus each 4g, fresh mulberry branches, fresh peach branches, fresh 40g of elm branch, fresh willow branch and fresh pagoda tree branch, 350g of red lead

[0048] Preparation

[0049] 1) Aconitum aconitum, dried blood, hippocampus, araceae, and pinellia are crushed into fine powder, sieved, and mixed;

[0050] 2) Eleven kinds of medicinal materials such as Red Earth Huoquan, etc. Weigh the medicinal materials according to the proportion of the prescription, add 7.5 times the amount of 56% ethanol, reflux extraction once, extract for the first time for 3 hours, recover the extract with ethanol, concentrate, dry, and pulverize to obtain a paste pink;

[0051] 3) Take the pharmaceutical excipient matrix rosin: beeswax: sesame oil: lanolin = 10:2:1:1, penetration enhancer 1% azone-1% menthol, heat to melt, conti...

Embodiment 2

[0053] Prescription: Red soil Poria, safflower, Qingfengteng, raw shrug, iron chopsticks, Jianxuefei each 30g, Aracea, Pinellia, Aconitum 3g each, blood dried out, hippocampus 5g each, fresh mulberry branches, fresh peach branches, fresh 50g each of elm branch, fresh willow branch and fresh pagoda tree branch, 440g of red lead

[0054] Preparation:

[0055] 1) Aconitum aconitum, dried blood, hippocampus, araceae, and pinellia are crushed into fine powder, sieved, and mixed;

[0056] 2) Eleven kinds of medicinal materials such as Hongtuhuoquan, etc. Weigh the medicinal materials according to the proportion of the prescription, add 6 times the amount of 70% ethanol, reflux extraction twice, and extract for 2 hours for the first time. The extract is recovered by ethanol, concentrated, dried, and crushed to obtain a paste pink;

[0057] 3) Take the pharmaceutical excipient matrix rosin: beeswax: sesame oil: lanolin = 10:2:1:1, penetration enhancer 1% azone-1% menthol, heat to me...

Embodiment 3

[0059] Prescription: Red soil Poria cocos, safflower, Qingfengteng, raw shrug, iron chopsticks, Jianxuefei each 40g, Aracea, Pinellia, Aconitum each 4g, blood dried blood, hippocampus each 6g, fresh mulberry branches, fresh peach branches, fresh 60g of elm branch, fresh willow branch and fresh pagoda tree branch, 520g of red lead

[0060] Preparation:

[0061] 1) Aconitum aconitum, dried blood, hippocampus, araceae, and pinellia are crushed into fine powder, sieved, and mixed;

[0062] 2) Eleven kinds of medicinal materials such as Hongtuhuoquan, etc. Weigh the medicinal materials according to the proportion of the prescription, add 4.5 times the amount of 84% ethanol, reflux extraction for 3 times, the first extraction is 1h, the extract is recovered by ethanol, concentrated, dried, and crushed to obtain a paste pink;

[0063] 3) Take the pharmaceutical excipient matrix rosin: beeswax: sesame oil: lanolin = 10:2:1:1, penetration enhancer 1% azone-1% menthol, heat to melt, c...

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PUM

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Abstract

The invention discloses a composition for treating hyperostosis and joint arthralgia spasm pain as well as a preparation method of the composition. The composition is prepared from the following components in parts by weight: 20 to 40 parts of red smilax glabr, 20 to 40 parts of flos carthami, 20 to 40 parts of caulis sinomenii, 20 to 40 parts of pyrrosia leaf, 20 to 40 parts of root of wintersweet, 20 to 40 parts of spinyleaf pricklyash root, 2 to 4 parts of rhizoma arisaematis, 2 to 4 parts of rhizoma pinelliae, 2 to 4 parts of radix aconiti agrestis, 4 to 6 parts of sangusis draconis and 4to 6 parts of sea horse, 40 to 60 parts of fresh ramulus mori, 40 to 60 parts of fresh peach twig, 40 to 60 parts of fresh ulmus pumila, 40 to 60 parts of fresh willow twig, 40 to 60 parts of Japanesepagodatree juvenile branchlet, 350 to 520 parts of red lead and pharmaceutically effective adjuvants. According to the preparation method of the composition, disclosed by the invention, an extractionprocess, a matrix and a forming process of an original preparation are changed, so that the conditions that pharmaceutical ingredients are easily destroyed at high temperature, produce air pollutionand the like in the original process are avoided. An original black paste dosage form is replaced with a new dosage form; the new dosage form has the advantages of definite curative effects, high safety, easiness in uncovering and pasting, no pollution to clothes, no poisonous lead elements or skin sensitizing property in the original preparation and no pollution to the environment; huge economicbenefits can be obtained when the composition for treating the hyperostosis and the joint arthralgia spasm pain is put into production.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and specifically relates to an ointment for treating hyperosteogeny and arthralgia and a preparation method thereof. Background technique [0002] Transdermal drug delivery systems are an attractive and challenging emerging field of pharmacy, and have been reported to be among the top 50 best-selling drugs in the world since the nitroglycerin patch was introduced in the 1980s. Transdermal preparation products have irreplaceable functional advantages and broad market prospects of other preparations. People in the medical field recognize that transdermal preparations are the most dynamic and rapidly growing pharmaceutical industry in the 21st century. With the development of medicine, the research on transdermal preparations of traditional Chinese medicine is getting more and more in-depth research. Traditional Chinese medicine has the advantages of low toxicity, l...

Claims

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Application Information

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IPC IPC(8): A61K36/90A61K36/896A61K9/70A61K47/46A61P29/00A61P19/02A61P19/08A61K35/60A61K33/24
CPCA61K36/90A61K9/7023A61K33/24A61K35/60A61K36/11A61K36/185A61K36/286A61K36/489A61K36/59A61K36/605A61K36/714A61K36/736A61K36/758A61K36/76A61K36/8884A61K36/8888A61K36/889A61K36/896A61K47/46A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 周宁王晓春白志文林必芬其他发明人请求不公开姓名
Owner GUOYAOJITUAN TONGJITANG (GUIZHOU) PHARMA CO LTD
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