High-temperature heat-resistant heat sealant for high-speed drug-packing machine for blister packaging of medicines and preparation method thereof
A blister packaging, high-speed technology, applied in the direction of adhesives, epoxy glue, adhesive types, etc., can solve the problems of non-existence, poor adhesion, poor hydrolysis resistance, etc., and achieve wide application range and stability of the adhesive layer Good, the effect of improving hydrolysis resistance and high temperature resistance
A blister packaging, high-speed technology, applied in the direction of adhesives, epoxy glue, adhesive types, etc., can solve the problems of non-existence, poor adhesion, poor hydrolysis resistance, etc., and achieve wide application range and stability of the adhesive layer Good, the effect of improving hydrolysis resistance and high temperature resistance
CN108264874BActive Publication Date: 2020-06-05SHANGHAI CHENGYING NEW MATERIALS +1
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Embodiment 1
[0039] This example relates to a high-speed heat-resistant heat-sealing glue for a drug blister packaging high-speed drug packaging machine. The specific formula is shown in Table 1. The preparation method includes the following steps:
[0040] (1) First put all the solvents into the reaction kettle according to the proportion and stir;
[0041] (2) Keep stirring and drop the modified polyolefin and modified epoxy into the reaction kettle successively, and stir for 1-2 hours;
[0042] (3) Slowly put the additives into the reaction kettle after mixing evenly, and stir at high speed for 0.5-1 hour;
[0043] (4) After mixing evenly, shut down and ripen for 10-12 hours;
[0044] (5) Measure the solid content and adjust to the theoretical value;
[0045] (6) Slowly stir again for 1-2 hours, cool, filter with a 250-mesh filter, weigh and pack.
Embodiment 2-5
[0047] Examples 2-5 respectively relate to a high-temperature heat-resistant heat-sealing glue used in a high-speed drug packaging machine for blister packaging of medicines.
[0048] Table 1
[0049]
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The invention provides a high temperature-resistant heat-sealing adhesive for a high-speed medicine packaging machine for medicine blister packaging. The high temperature-resistant heat-sealing adhesive comprises, by mass, 20-39.9% of modified polyolefin resin, 10-20% of modified epoxy resin, 50-60% of a solvent and 0.1-0.5% of an assistant. A preparation method of the high temperature-resistant heat-sealing adhesive comprises the following steps: S1, adding the solvent into a reaction kettle, performing stirring to achieve uniform mixing, sequentially adding the modified polyolefin resin andthe modified epoxy resin while stirring, and stirring and uniformly mixing the solvent, the modified polyolefin resin and the modified epoxy resin; S2, adding the assistant to a mixed solution obtained in step S1, performing high-speed stirring to achieve uniform mixing, and performing downtime curing; and S3, measuring the solid content, adjusting the solid content to a theoretical value, and performing stirring, cooling and filtering. Compared with heat-sealing adhesives in the prior art, the heat-sealing adhesive in the invention has the following advantages: no leakage sealing, no scorching crease marks and no peculiar smell are achieved during high-temperature and high-speed sealing using the medicine packaging machine; the heat-sealing strength is high, so product demands are met; anadhesive layer has a good stability, and the strength of a coating film does not change after the coating film is stored for one year; and the heat-sealing adhesive has a wide application range.
Description
technical field [0001] The invention relates to the technical field of high-temperature heat-resistant heat-sealing glue in drug blister packaging, in particular to a high-temperature-resistant heat-sealing glue used in a high-speed drug packaging machine for medicine blister packaging and a preparation method thereof. Background technique [0002] With the continuous rapid development of my country's economic situation, the continuous improvement of people's living standards, the corresponding rapid development of the pharmaceutical industry, and the development of modern machinery in the direction of high precision, high speed and low cost, these factors have directly promoted the rapid development of pharmaceutical companies. develop. In order to make full use of the pharmaceutical equipment of pharmaceutical companies, high-speed drug packaging is the most direct, efficient and convenient way, but it is also accompanied by some inevitable problems. [0003] When the medi...
Claims
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Patent Timeline
05 Jun 2020
Publication
CN108264874B
- IPC
- C09J151/06; C09J163/00; C09J123/08; C09J127/06; C09J163/10
- CPC
- C08L2201/08; C08L2205/025; C08L2205/035; C09J123/0853; C09J127/06; C09J151/06; C09J163/00; C08L63/00
- Inventors
- 董海普; 滕飞