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Applications of puerarin in preparation of drug used for preventing and treating pig virus infection, drug used for preventing and treating pig virus infection, and pig feed additive

A virus infection, puerarin technology, applied in animal feed, antiviral agent, application and other directions, can solve problems such as harm to pig production, unstable vaccine prevention effect, no report on the use of puerarin, etc., to prevent and cure pig virus. Infection, no toxic side effects, high safety effect

Active Publication Date: 2018-07-13
HUBEI HAOHUA BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, there is no report on the use of puerarin in the infection of porcine epidemic diarrhea virus or porcine circovirus type 2
In view of the fact that the infection of porcine epidemic diarrhea virus or porcine circovirus type 2 seriously endangers pig production, and the preventive effect of existing vaccines is unstable, it is of great significance to develop the use of puerarin in the preparation of drugs for the treatment or prevention of porcine virus infection

Method used

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  • Applications of puerarin in preparation of drug used for preventing and treating pig virus infection, drug used for preventing and treating pig virus infection, and pig feed additive

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A medicine for preventing and treating swine viral infections, the medicine for preventing and treating swine virus infections is an oral liquid, and the pharmaceutical excipients are absolute ethanol and Tween-80, and each 100mL oral liquid includes: puerarin 20mg, absolute ethanol 10mL, Tween-8020mL, the rest is water for injection.

[0036] Preparation method: first dissolve puerarin in absolute ethanol, then add Tween-80, and finally slowly add water for injection to make up to 100 mL to prepare a puerarin oral liquid (0.2 mg / mL).

[0037] If it is used as a medicine to prevent swine virus infection, 2.4 mL of oral liquid can be added to the feed and used throughout the feeding cycle.

[0038] If it is used as a medicine for clinical treatment of swine virus infection, 6mL of oral liquid can be administered orally; or 6mL of oral liquid can be fed directly; or 6mL of oral liquid can be added to the feed for use, three times a day, morning, night and evening , Continuous u...

Embodiment 2

[0040] A medicine for preventing and treating swine viral infections, the medicine for preventing and treating swine virus infections is an oral liquid, and the pharmaceutical excipients are absolute ethanol and Tween-80, and each 100mL oral liquid includes: puerarin 50mg, absolute ethanol 20mL, Tween-8030mL, the rest is water for injection.

[0041] Preparation method: first dissolve puerarin in absolute ethanol, then add Tween-80, and finally slowly add water for injection to make up to 100 mL to prepare a puerarin oral liquid (0.5 mg / mL).

[0042] If it is used as a medicine to prevent swine virus infection, 2.4 mL of oral liquid can be added to the feed and used throughout the feeding cycle.

[0043] If it is used as a medicine for clinical treatment of swine virus infection, 6mL of oral liquid can be administered orally; or 6mL of oral liquid can be fed directly; or 6mL of oral liquid can be added to the feed for use, three times a day, morning, night and evening , Continuous u...

Embodiment 3

[0045] A drug for preventing and treating swine viral infection, the drug for preventing and treating swine virus infection is an oral liquid, and the pharmaceutical excipients are absolute ethanol and Tween-80, and each 100mL oral liquid includes: puerarin 100mg, absolute ethanol 40mL, Tween-8050mL, the rest is water for injection.

[0046] Preparation method: first dissolve puerarin in absolute ethanol, then add Tween-80, and finally slowly add water for injection to make up to 100 mL to prepare a puerarin oral liquid (1.0 mg / mL).

[0047] If it is used as a medicine to prevent swine virus infection, 2.4 mL of oral liquid can be added to the feed and used throughout the feeding cycle.

[0048] If it is used as a medicine for the clinical treatment of swine virus infection, 6mL of oral liquid can be administered orally; or 6mL of oral liquid can be fed directly; or 6mL of oral liquid can be added to the feed for use, three times a day, morning, night and evening , Continuous use fo...

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PUM

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Abstract

The invention discloses applications of puerarin in preparation of a drug used for preventing and treating pig virus infection, the drug used for preventing and treating pig virus infection, and a pigfeed additive. The drug comprises 20 to 80wt% or 0.2 to 2.0mg / ml of puerarin, and a pharmaceutical adjuvant. The drug is high in safety, can be used for preventing and treating pig virus infection effectively, and reducing the mortality of infected pigs; and no toxic or side effect is caused.

Description

Technical field [0001] The present invention relates to the technical field of pig virus prevention and treatment, in particular to the use of puerarin in preparing medicines for preventing and treating pig virus infections, medicines for preventing and treating pig virus infections and pig feed additives. Background technique [0002] Porcine epidemic diarrhea (PED) caused by porcine epidemic diarrhea virus (PEDV) is an acute intestinal infectious disease of pigs. The main clinical symptoms are drastically reduced feed intake, watery diarrhea accompanied by vomiting, and even dehydration in severe cases. Pigs of all ages and breeds may be infected and the most severely affected are lactating piglets. The morbidity rate is as high as 100%, and it is one of the main diseases leading to the early death of piglets. Under natural conditions, the incubation period of piglets infected with PEDV is 1 to 2 days, and the incubation period of artificial infection is between 8 and 24 hours...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P31/14A23K50/30A23K20/00
CPCA23K20/00A23K50/30A61K31/352
Inventor 侯永清吴涛易丹丁斌鹰
Owner HUBEI HAOHUA BIOTECH